Cancer biologist with extensive research experience in the fields of osteoblast
biology and hematopoiesis and a longstanding interest in exploring genetic and epigenetic
mechanisms that control onset and progression of the cancer phenotype, especially in
myelogenous leukemia. 

Gene Regulation

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Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells (with Margaretha Van der Deen, Mohammad Q. Hassan, Jitesh Pratap, Nadiya M. Teplyuk, Daniel W. Young, Amjad Javed, Jane B. Lian, Martin A. Montecino, Janet L. Stein, Gary S. Stein, and Andre J. Van Wijnen), Methods in molecular biology (Clifton, N.J.) (2008)
 

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Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal (with Amjad Javed, Jong-Sup Bae, Faiza Afzal, Soraya E. Gutierrez, Jitesh Pratap, Yang Lou, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian), The Journal of biological chemistry (2008)
 

Link

Analysis of in vivo gene expression using epitope-tagged proteins (with Amjad Javed, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly Stacy Harrington, Hayk Hovhannisyan, Brian C. Cho, Jitesh Pratap, Shirwin M. Pockwinse, Martin Montecino, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein), Methods in molecular biology (Clifton, N.J.) (2004)
 

Link

Chromatin immunoprecipitation (with Amjad Javed, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly Stacy Harrington, Hayk Hovhannisyan, Brian C. Cho, Jitesh Pratap, Shirwin M. Pockwinse, Martin Montecino, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein), Methods in molecular biology (Clifton, N.J.) (2004)
 

Link

Immunofluorescence analysis using epitope-tagged proteins: in vitro system (with Amjad Javed, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly Stacy Harrington, Hayk Hovhannisyan, Brian C. Cho, Jitesh Pratap, Shirwin M. Pockwinse, Martin A. Montecino, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein), Methods in molecular biology (Clifton, N.J.) (2004)
 

Epigenetic Regulation

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Transcription-factor-mediated epigenetic control of cell fate and lineage commitment (with Gary S. Stein, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin A. Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande, and Mohammad Q. Hassan), Biochemistry and cell biology = Biochimie et biologie cellulaire (2009)
 

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Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes (with Sandhya Pande, Syed A. Ali, Christopher Dowdy, Kosei Ito, Yoshiaki Ito, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Journal of cellular physiology (2008)
 

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Phenotypic transcription factors epigenetically mediate cell growth control (with Syed A. Ali, Caroline S. Dacwag, Nunciada Salma, Daniel W. Young, A. Rauf Shakoori, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Anthony N. Imbalzano, Gary S. Stein, and Janet L. Stein), Proceedings of the National Academy of Sciences of the United States of America (2008)
 

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Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2 (with Daniel W. Young, Mohammad Q. Hassan, Xiaoqing Yang, Mario Galindo, Amjad Javed, Paul S. Furcinitti, David S. Lapointe, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2007)
 

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Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2 (with Daniel W. Young, Mohammad Q. Hassan, Jitesh Pratap, Mario Galindo, Suk Hee Lee, Xiaoqing Yang, Ronglin Xie, Amjad Javed, Jean. M. Underwood, Paul S. Furcinitti, Anthony N. Imbalzano, Sheldon Penman, Jeffrey A. Nickerson, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Nature (2007)
 

Nuclear Organization

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Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer (with Gary S. Stein, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin A. Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande, and Mohammad Q. Hassan), Annals of the New York Academy of Sciences (2009)
 

Link

Nuclear microenvironments and cancer (with Gary S. Stein, James R. Davie, and J. Randy Knowlton), Journal of cellular biochemistry (2008)
 

Link

Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer (with Gary S. Stein, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin A. Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande, and Mohammad Q. Hassan), Journal of cellular biochemistry (2008)
 

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In situ nuclear organization of regulatory machinery (with Shirwin M. Pockwinse, Ricardo F. Medina, Rachit Bakshi, Krishna P. Kota, Syed A. Ali, Daniel W. Young, Jeffrey A. Nickerson, Amjad Javed, Martin A. Montecino, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein), Methods in molecular biology (Clifton, N.J.) (2008)
 

Link

Nuclear microenvironments in biological control and cancer (with Daniel W. Young, Amjad Javed, Jitesh Pratap, Martin A. Montecino, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein), Nature reviews. Cancer (2007)
 

Osteogenesis

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Specific residues of Runx2 are obligatory for formation of BMP2-induced Runx2-Smad complex to promote osteoblast differentiation (with Amjad Javed, Faiza Afzal, Jong S. Bae, Soraya E. Guttierrez, Jitesh Pratap, Andre J. van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian), Cells Tissues Organs (2009)
 

Link

Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells (with Jitesh Pratap, John J. Wixted, Tripti Gaur, Jason Dobson, Karthiga Devi Gokul, Sadiq Hussain, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian), Cancer research (2008)
 

Link

Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential (with Sandhya Pande, Jitesh Pratap, Tripti Gaur, Simina R. Grigoriu, Syed A. Ali, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2007)
 

Link

Alterations in intranuclear localization of Runx2 affect biological activity (with Amjad Javed, Jitesh Pratap, Tania M. Schroeder, Jennifer J. Westendorf, Jane B. Lian, Andre J. Van Wijnen, Gary S. Stein, and Janet L. Stein), Journal of cellular physiology (2006)
 

Link

Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression (with Gary S. Stein, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, Martin A. Montecino, Amjad Javed, Daniel W. Young, Je-Yong Choi, and Shirwin M. Pockwinse), Oncogene (2004)
 

Acute Myeloid Leukemia

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Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network (with Christopher R. Dowdy, Andre J. Van Wijnen, Jane B. Lian, Azra Raza, Janet L. Stein, Carlo M. Croce, and Gary S. Stein), Cancer research (2009)
 

Link

Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice (with Ya-Huei Kuo, Svetlana Gornostaeva, Toshihisa Komori, Gary S. Stein, and Lucio H. Castilla), Blood (2009)
 

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The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes (with Rachit Bakshi, Sandhya Pande, Mohammad Q. Hassan, Daniel W. Young, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Journal of cell science (2008)
 

Link

Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype (with Diana Vradii, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2005)
 

MicroRNAs

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MicroRNAs 221 and 222 bypass quiescence and compromise cell survival (with Ricardo F. Medina, Chang-Gong Liu, Janet L. Stein, Andre J. Van Wijnen, Carlo M. Croce, and Gary S. Stein), Cancer research (2008)
 

Cell Proliferation

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Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Link

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Carlo M. Croce, Je-Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan, and Daniel W. Young), Advances in enzyme regulation (2010)
 

Link

The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif (with Ricardo F. Medina, Timothy F. Buck, Angela Miele, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Biochemistry (2008)
 

Link

An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition (with Gary S. Stein, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian, Martin A. Montecino, and Corey D. Braastad), Journal of cellular physiology (2006)
 

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HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition (with Angela Miele, Corey D. Braastad, William F. Holmes, Partha Mitra, Ricardo F. Medina, Ronglin Xie, Xin Ye, Yue Wei, J. Wade Harper, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Molecular and cellular biology (2005)
 

Multiprotein Complexes

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Phenotype

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Link

Mitotic bookmarking of genes: a novel dimension to epigenetic control (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Nature reviews. Genetics (2010)
 

Link

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Carlo M. Croce, Je-Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan, and Daniel W. Young), Advances in enzyme regulation (2010)
 

Mammals

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Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Intranuclear Space

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Subnuclear localization and intranuclear trafficking of transcription factors (with Ricardo F. Medina, Shirwin M. Pockwinse, Rachit Bakshi, Krishna P. Kota, Syed A. Ali, Daniel W. Young, Jeffrey A. Nickerson, Amjad Javed, Martin A. Montecino, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein), Methods in molecular biology (Clifton, N.J.) (2010)
 

Cell Line, Tumor

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Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Link

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes (with Syed A. Ali, James G. Dobson Jr., A. Rauf Shakoori, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2010)
 

Humans

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Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Link

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes (with Syed A. Ali, James G. Dobson Jr., A. Rauf Shakoori, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2010)
 

Link

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Carlo M. Croce, Je-Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan, and Daniel W. Young), Advances in enzyme regulation (2010)
 

*Epigenesis, Genetic

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Link

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes (with Syed A. Ali, James G. Dobson Jr., A. Rauf Shakoori, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2010)
 

Link

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Carlo M. Croce, Je-Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan, and Daniel W. Young), Advances in enzyme regulation (2010)
 

RNA, Untranslated

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Cell Differentiation

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Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Epigenesis, Genetic

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Bookmarking the genome: maintenance of epigenetic information (with Daniel W. Young, Martin A. Montecino, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian, and Gary S. Stein), The Journal of biological chemistry (2011)
 

Link

An architectural genetic and epigenetic perspective (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jeffrey A. Nickerson, Martin A. Montecino, and Daniel W. Young), Integrative biology : quantitative biosciences from nano to macro (2010)
 

Link

Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments (with Gary S. Stein, Andre J. Van Wijnen, Jane B. Lian, Anthony N. Imbalzano, Martin A. Montecino, Jane B. Lian, Jeffrey A. Nickerson, and Janet L. Stein), Critical reviews in eukaryotic gene expression (2010)
 

Link

Mitotic bookmarking of genes: a novel dimension to epigenetic control (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Nature reviews. Genetics (2010)
 

Adenosine Triphosphatases

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

*Neoplasms

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Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Carlo M. Croce, Je-Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan, and Daniel W. Young), Advances in enzyme regulation (2010)
 

Mitosis

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Link

Mitotic bookmarking of genes: a novel dimension to epigenetic control (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Nature reviews. Genetics (2010)
 

Gene Expression Regulation

Link

An architectural genetic and epigenetic perspective (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jeffrey A. Nickerson, Martin A. Montecino, and Daniel W. Young), Integrative biology : quantitative biosciences from nano to macro (2010)
 

Link

Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments (with Gary S. Stein, Andre J. Van Wijnen, Jane B. Lian, Anthony N. Imbalzano, Martin A. Montecino, Jane B. Lian, Jeffrey A. Nickerson, and Janet L. Stein), Critical reviews in eukaryotic gene expression (2010)
 

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Promoter Regions, Genetic

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Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Carlo M. Croce, Je-Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan, and Daniel W. Young), Advances in enzyme regulation (2010)
 

DNA Methylation

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Link

Mitotic bookmarking of genes: a novel dimension to epigenetic control (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Nature reviews. Genetics (2010)
 

RNA, Ribosomal

Link

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes (with Syed A. Ali, James G. Dobson Jr., A. Rauf Shakoori, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2010)
 

DNA-Binding Proteins

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Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Repressor Proteins

Link

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes (with Syed A. Ali, James G. Dobson Jr., A. Rauf Shakoori, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2010)
 

Nucleolus Organizer Region

Link

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes (with Syed A. Ali, James G. Dobson Jr., A. Rauf Shakoori, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2010)
 

Protein Processing, Post-Translational

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Immunoprecipitation

Link

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes (with Syed A. Ali, James G. Dobson Jr., A. Rauf Shakoori, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2010)
 

*Transcription, Genetic

Link

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes (with Syed A. Ali, James G. Dobson Jr., A. Rauf Shakoori, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2010)
 

Models, Genetic

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Transcription Factors

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An architectural genetic and epigenetic perspective (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jeffrey A. Nickerson, Martin A. Montecino, and Daniel W. Young), Integrative biology : quantitative biosciences from nano to macro (2010)
 

Link

Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments (with Gary S. Stein, Andre J. Van Wijnen, Jane B. Lian, Anthony N. Imbalzano, Martin A. Montecino, Jane B. Lian, Jeffrey A. Nickerson, and Janet L. Stein), Critical reviews in eukaryotic gene expression (2010)
 

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Link

Mitotic bookmarking of genes: a novel dimension to epigenetic control (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Nature reviews. Genetics (2010)
 

Link

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Carlo M. Croce, Je-Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan, and Daniel W. Young), Advances in enzyme regulation (2010)
 

Animals

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Link

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Carlo M. Croce, Je-Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan, and Daniel W. Young), Advances in enzyme regulation (2010)
 

Microscopy, Fluorescence

Link

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes (with Syed A. Ali, James G. Dobson Jr., A. Rauf Shakoori, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Proceedings of the National Academy of Sciences of the United States of America (2010)
 

Histones

Link

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein), Molecular and cellular biology (2010)
 

Link

Mitotic bookmarking of genes: a novel dimension to epigenetic control (with Daniel W. Young, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Nature reviews. Genetics (2010)
 

*Gene Expression Regulation

Link

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Carlo M. Croce, Je-Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan, and Daniel W. Young), Advances in enzyme regulation (2010)
 

Core Binding Factor Alpha 2 Subunit

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Cell Nucleus

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Female

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Mutation

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Genotype

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Transcriptional Activation

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Male

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Structure-Activity Relationship

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Mutant Proteins

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Gene Expression Regulation, Developmental

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Mice

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Protein Binding

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

*Hematopoiesis

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Hematopoietic Stem Cells

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Embryo, Mammalian

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Protein Structure, Tertiary

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Heterozygote

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Crosses, Genetic

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Protein Transport

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation (with Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein), Human molecular genetics (2010)
 

Intracellular Space

Link

An architectural genetic and epigenetic perspective (with Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jeffrey A. Nickerson, Martin A. Montecino, and Daniel W. Young), Integrative biology : quantitative biosciences from nano to macro (2010)
 

Link

Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments (with Gary S. Stein, Andre J. Van Wijnen, Jane B. Lian, Anthony N. Imbalzano, Martin A. Montecino, Jane B. Lian, Jeffrey A. Nickerson, and Janet L. Stein), Critical reviews in eukaryotic gene expression (2010)