Dr. Sara Allstadt Frazier’s research focuses on advancing novel therapeutics into
clinical trials. She works to investigate therapies that advance cancer treatment and
incorporate seamlessly into the clinic. She is currently investigating the
thiazolidinedione class of drugs and their potential anti-cancer effects through their
interaction with peroxisome proliferator activated receptors. 

BACKGROUND 

Dr. Frazier graduated from the Auburn University College of Veterinary Medicine in 2002.
After graduation, she returned home to general practice in South Alabama, leaving to
pursue her dream of becoming a specialist after three years as a small town general
practice veterinarian. After completing an internship in small animal medicine and
surgery and an oncology specialty internship, she completed her Residency in Medical
Oncology at the University of California-Davis and achieved board-certification in the
American College of Veterinary Internal Medicine specialty of Oncology. She joined the
faculty at UC Davis in 2010 and remained there until August of 2012, when she moved east
to join the faculty at the University of Tennessee. 

Dr. Frazier enjoys the diversity of the academic environment- the invigoration of
inspiring students to be fantastic veterinarians, the challenges and successes of patient
interaction, the advantage of having multiple specialists working alongside each other,
along with the thrill of advancing research for the betterment of cancer treatment in
both animals and humans alike. 

Articles

OpenURL

Phase I clinical trial of oral rosiglitazone in combination with intravenous carboplatin in cancer-bearing dogs (with D S. McKemie, T A. Guerrero, H Lachapelle, K A. Skorupski, P H. Kass, and C O. Rodriguez CO Jr.), Veterinary and Comparative Oncology (2012)
 

Gemcitabine degradation in whole blood from humans, dogs, cats, and horses (with Danielle O'Brien, Teri Guerrero, Robert B. Rebhun, Katherine A. Skorupski, and Carlos O. Rodriguez Jr), Journal of Veterinary Science and Technology (2012)
 

OpenURL

Outcome in dogs with surgically resected oral fibrosarcoma (1997-2008). (with S M. Johns, J Ortega, A L. Zwingenberger, M S. Kent, G M. Hammond, C O. Rodriguez Jr., M A. Steffey, and K A. Skorupski), Veterinary and Comparative Oncology (2012)
 

OpenURL

CHOP chemotherapy for the treatment of canine multicentric T-cell lymphoma (with R B. Rebhun, M S. Kent, S AEB Borrofka, K Skorupski, and C O. Rodriguez), Veterinary and Comparative Oncology (2011)
 

OpenURL

Evaluation of an extractionless high-performance liquid chromatography-tandem mass spectrometry method for detection and quantitation of rosiglitazone in canine plasma. (with D S. McKemie, T A. Guerroro, K A. Skorupski, and C O. Rodriguez Jr.), American Journal of Veterinary Research (2011)