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Disassembly of noncovalent amphiphilic polymers with proteins and utility in pattern sensing

EN Savariar
S Ghosh
DC Gonzalez
S Thayumanavan

Abstract

A simple strategy for pattern recognition of proteins through micellar disassembly is introduced. Five different noncovalently assembled receptors have been generated, and the disassembly was studied by monitoring the encapsulated dye release in response to five different proteins. The disassembly induced fluorescence change of the guest molecule produces protein-specific patterns.

Suggested Citation

EN Savariar, S Ghosh, DC Gonzalez, and S Thayumanavan. "Disassembly of noncovalent amphiphilic polymers with proteins and utility in pattern sensing" Journal of the American Chemical Society 130.16 (2008): 5416.
Available at: http://works.bepress.com/sankaran_thayumanavan/23