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BioSMART: An integrated programme to enhance graduate skills in biomedical science (with Peter J. Johnson, Sonya Marshall-Gradisnik, Kevin Ashton, John Leggett, and Debra Henly), Innovations in teaching and learning: Approaches to professional development from across the disciplines: Volume 1, Bond University (2010)
The BioSMART (Scientific Methods for Analytical and Reasoning Skills and Critical Thinking) program was developed...
Blood kinetics of four intraperitoneally administered therapeutic candidate bacteriophages in healthy and neutropenic mice (with Jumpei Uchiyama, Yoshihiro Maeda, Iyo Takemura, Hiroshi Wakiguchi, and Shigenobu Matsuzaki), Microbiology and immunology (2009)
Due to multiple-drug resistant bacteria, phage therapy is being revisited. Although most animal experiments focus...
Blood kinetics of four intraperitoneally administered therapeutic candidate bacteriophages in healthy and neutropenic mice (with Jumpei Uchiyama, Yoshihiro Maeda, Iyo Takemura, Hiroshi Wakiguchi, and Shigenobu Matsuzaki), Microbiology and immunology (2009)
Due to multiple-drug resistant bacteria, phage therapy is being revisited. Although most animal experiments focus...
Pharmacologic responses of the mouse urinary bladder (with A. Canda Erdem and Christopher R. Chapple), Central European journal of medicine (2009)
The aim of the study was to determine pathways involved in contraction and relaxation of...
Pharmacologic responses of the mouse urinary bladder (with A. Canda Erdem and Christopher R. Chapple), Central European journal of medicine (2009)
The aim of the study was to determine pathways involved in contraction and relaxation of...
Spontaneous contractions of the pig urinary bladder: The effect of ATP-sensitive potassium channels and the role of the mucosa (with Hironobu Akino, Christopher R. Chapple, Neil McKay, Rebecca L. Cross, Shigetaka Murakami, Osamu Yokoyama, and Donna J. Sellers), Health Sciences & Medicine papers (2008)
To investigate the influence of the mucosa on the inhibitory effects of the ATP-sensitive potassium...
Characterization of the α1-adrenoceptor subtype mediating contractions of the pig internal anal sphincter (with K. A. Mills and N. Hausman), Health Sciences & Medicine papers (2008)
Background and purpose: The internal anal sphincter has been shown to contract in response to...
Contractile properties of the pig bladder mucosa in response to neurokinin A: A role for myofibroblasts? (with P Sadananda and E Burcher), Health Sciences & Medicine papers (2008)
Background and purpose: The bladder urothelium is now known to have active properties. Our aim...
Enhanced ATP release from the urothelium of patients with painful bladder syndrome: A possible pathophysiological explanation (with Vivek Kumar, Christopher Chapple, and Ann Marie Surprenant), Health Sciences & Medicine papers (2007)
PURPOSE: We established the level of adenosine triphosphate release by the urothelium in patients with...
Bladder afferent sensitivity in wildtype and TRPV1 knockout mice (with D Daly, W Rong, C Chapple, and D Grundy), Health Sciences & Medicine papers (2007)
Understanding bladder afferent pathways may reveal novel targets for therapy of lower urinary tract disorders...
Demonstration of 5-HT3 receptor function and expression in the mouse bladder (with N Chetty, I M. Coupar, and K P. Kerr), Health Sciences & Medicine papers (2007)
Extract:
The aim of this study was to demonstrate the presence of 5-HT3 receptors in...
The role of the urothelium in mediating bladder responses to isoprenaline (with Shigetaka Murakami, Christopher Chapple, Hironobu Akino, and Donna Sellers), Health Sciences & Medicine papers (2007)
To investigate whether the responses of the pig bladder to isoprenaline (a nonselective β-adrenoceptor agonist)...
Influence of β1 -adrenoceptor polymorphisms on the expression of β1 -adrenoceptors in human lung tissue (with L. J. Kay, S. K. Suvarna, and Peter T. Peachell), Health Sciences & Medicine papers (2006)
Human lung tissue contains both β2 - and β1 -adrenoceptors at a reported ratio of...
The Effect of â-Adrenoceptor Agonists on Detrusor Contraction in the Presence and Absence of Urothelium (with Shigetaka Murakami, Christopher R. Chapple, and Hironobu Akino), Health Sciences & Medicine papers (2006)
It is known that stimulating muscarinic receptors in bladder urothelium causes the release of nitric...
The Effect of â-Adrenoceptor Agonists on Detrusor Contraction in the Presence and Absence of Urothelium (with Shigetaka Murakami, Christopher R. Chapple, and Hironobu Akino), Health Sciences & Medicine papers (2006)
It is known that stimulating muscarinic receptors in bladder urothelium causes the release of nitric...
The Effect of Resting Tension, pH and Temperature on Urothelium-Derived Inhibitory Factor Attenuation of Detrustor Contractility (with R. L. Cross and Christopher R. Chapple), Health Sciences & Medicine papers (2006)
The presence of urothelium inhibits maximal bladder contractions by approximately 50% in response to carbachol...
The Effect of β-Adrenoceptor Agonists on Detrusor Contraction in the Presence and Absence of Urothelium (with S. Murakami, Christopher R. Chapple, and H. Akino), Health Sciences & Medicine papers (2006)
It is known that stimulating muscarinic receptors in bladder urothelium causes the release of nitric...
The α1A/L-Adrenoceptor Subtype Mediates Contraction of the Internal Anal Sphincter to Noradrenaline (with A. Shorthouse and N. Hausman), Health Sciences & Medicine papers (2006)
Contraction of the internal anal sphincter contributes 50-85% towards resting anal tone. Small clinical trials...
Human Idiopathic and Neurogenic Overactive Bladders and the Role of M2 Muscarinic Receptors in Contraction (with Laurie A. Stevens and Christopher R. Chapple), Health Sciences & Medicine papers (2006)
Objectives: This study examines whether M2 receptors contribute to direct contraction of the detrusor in...
Alpha1A/L-adrenoceptors mediate contraction of the circular smooth muscle of the pig urethra (with K. Bagot), Health Sciences & Medicine papers (2006)
1. Sympathetically mediated urethral tone is essential for the maintenance of continence and involves the...
Muscarinic receptor function, density and G-protein coupling in the overactive diabetic rat bladder (with Laurie A. Stevens, Donna J. Sellers, Neil J. McKay, and Christopher R. Chapple), Health Sciences & Medicine papers (2006)
1. Bladder smooth muscle sensitivity to muscarinic agonists is increased in the overactive bladder. Treatment...
Depressed contractile responses to neurokinin A in idiopathic but not neurogenic overactive human detrusor muscle (with Donna J. Sellers, Christopher R. Chapple, Douglas P. W. Hay, and Russell Chess-Williams), European urology (2006)
Objective: The role of tachykinins such as neurokinin A in regulating bladder function is unclear,...