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The role of the urothelium in mediating bladder responses to isoprenaline

Shigetaka Murakami, Sheffield Hallam University
Christopher Chapple, Sheffield Hallam University
Hironobu Akino, Sheffield Hallam University
Donna Sellers, Sheffield Hallam University
Russ Chess-Williams, Bond University

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Interim status: Citation only.

Murakami, S., Chapple, C.R., Akino, H., Sellers, D.J. & Chess-Williams, R. (2007) The role of the urothelium in mediating bladder responses to isoprenaline. BJU International, Vol. 99, Iss. 3, pp. 669-673.

View BJU International homepage.
Copyright ©Official journal of the British Association of Urological Surgeons, the Urological Society of Australia and New Zealand and the International Journal of the Urological Society of India, 2007.

Abstract

To investigate whether the responses of the pig bladder to isoprenaline (a nonselective β-adrenoceptor agonist) are influenced by the presence of an intact urothelium and whether any influence might be attributed to the release of nitric oxide (NO), since stimulation of β-adrenoceptors induces a direct relaxation of detrusor smooth muscle and β-adrenoceptors are also present on the urothelium.

Suggested Citation

Shigetaka Murakami, Christopher Chapple, Hironobu Akino, Donna Sellers, and Russ Chess-Williams. "The role of the urothelium in mediating bladder responses to isoprenaline" Health Sciences & Medicine papers (2007).
Available at: http://works.bepress.com/russ_chess_williams/1



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