Qualifications Doctor of Philosophy - University of Wales, Cardiff, UK Bachelor of Science - University of Wales, Cardiff, UK Professor Chess-Williams' research interests and expertise lies in the autonomic innervation of the lower urinary tract and cardiovascular systems. Physiological/pathophysiological studies of these systems with the aim of identifying novel therapeutic targets. Physiology and pharmacology of bladder instability, benign prostatic hyperplasia, cardiac and vascular disease.
Articles
Adrenoceptor function and expression in bladder urothelium and lamina propria (with Christian Moro and Lotti Tajouri), Urology (2012)
Objective - To investigate the role of adrenoceptor subtypes in regulating the spontaneous contractile activity...
Non-adrenergic, non-cholinergic, non-purinergic contractions of the urothelium/lamina propria of the pig bladder (with Christian Moro), Autonomic and autacoid pharmacology (2012)
Summary
1. Acetylcholine, and to a lesser extent ATP, mediates neurogenic contractions of bladder smooth muscle....
Effects of pseudomonas aeruginosa virulence factor pyocyanin on human urothelial cell function and viability (with Catherine M. McDermott, Gary D. Grant, Anthony V. Perkins, Amelia J. McFarland, Andrew K. Davey, and Shailendra Anoopkumar-Dukie), The Journal of Urology (2012)
Purpose: We determined the effects of Pseudomonas aeruginosa virulence factor pyocyanin on human urothelial cell...
Contractile activity of the bladder urothelium/lamina propria and its regulation by nitric oxide (with Christian Moro and Charlotte Leeds), European journal of pharmacology (2012)
In the bladder, nitric oxide (NO) is released from neuronal and non-neuronal sources, but its...
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol (with Christian Moro and Jumpei Uchiyama), Urology (2011)
Objective: To investigate the effects of tissue stretch and muscarinic receptor stimulation on the spontaneous...
Book Chapters
Muscarinic agonists and antagonists: Effects on the urinary bladder (with Donna J. Sellers), Handbook of Experimental Pharmacology (2012)
Voiding of the bladder is the result of a parasympathetic muscarinic receptor activation of the...
BioSMART: An integrated programme to enhance graduate skills in biomedical science (with Peter J. Johnson, Sonya Marshall-Gradisnik, Kevin Ashton, John Leggett, and Debra Henly), Innovations in teaching and learning: Approaches to professional development from across the disciplines: Volume 1, Bond University (2010)
The BioSMART (Scientific Methods for Analytical and Reasoning Skills and Critical Thinking) program was developed...