I am interested in extensive statistical methods and applications to the research of biomedical science and public health. Two themes have been my current interest and from time to time they overlap with each other. The first one is theme is about making simultaneous inference on an ensemble of units, such as evaluating hospital profiling/ranking, various types of association evaluation in high-throughput genomic arrays; the other theme is the linear and nonlinear statistical methods that would be used to characterize nonlinear dose response relationship and the complex dynamics of biological systems.
Reverse Transcriptase Polymerase Chain Reaction
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Humans
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Time Factors
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Mothers
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Adolescent
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Female
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Vital and Health Statistics
Ranking USRDS Provider-Specific SMRs from 1998-2001 (with Thomas A. Louis, Susan M. Paddock, and Greg Ridgeway), Johns Hopkins University, Dept. of Biostatistics Working Papers (2004)
Provider profiling (ranking, "league tables") is prevalent in health services research. Similarly, comparing educational institutions...
Genotype
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Male
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Adult
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Prospective Studies
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Health Services Research
Ranking USRDS Provider-Specific SMRs from 1998-2001 (with Thomas A. Louis, Susan M. Paddock, and Greg Ridgeway), Johns Hopkins University, Dept. of Biostatistics Working Papers (2004)
Provider profiling (ranking, "league tables") is prevalent in health services research. Similarly, comparing educational institutions...
AIDS Serodiagnosis
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Child
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Anti-Retroviral Agents
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
HIV-1
Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue (with Maria Paz Gonzalez-Perez, Olivia O’Connell, W Matthew Sullivan, Jeanne Bell, Peter Simmonds, and Paul R. Clapham), Retrovirology (2012)
Background: Transmitted HIV-1 clade B or C R5 viruses have been reported to infect macrophages...
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Statistical Models
Ranking USRDS Provider-Specific SMRs from 1998-2001 (with Thomas A. Louis, Susan M. Paddock, and Greg Ridgeway), Johns Hopkins University, Dept. of Biostatistics Working Papers (2004)
Provider profiling (ranking, "league tables") is prevalent in health services research. Similarly, comparing educational institutions...
Loss Function Based Ranking in Two-Stage, Hierarchical Models (with Thomas A. Louis, Susan M. Paddock, and Greg Ridgeway), Johns Hopkins University, Dept. of Biostatistics Working Papers (2003)
Several authors have studied the performance of optimal, squared error loss (SEL) estimated ranks. Though...
HIV Infections
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
Statistical Theory and Methods
Loss Function Based Ranking in Two-Stage, Hierarchical Models (with Thomas A. Louis, Susan M. Paddock, and Greg Ridgeway), Johns Hopkins University, Dept. of Biostatistics Working Papers (2003)
Several authors have studied the performance of optimal, squared error loss (SEL) estimated ranks. Though...
Reproducibility of Results
Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR (with Nishaki Mehta, Sonia Trzmielina, Bareng A. S. Nonyane, Melissa N. Eliot, Andrea S. Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L. Sullivan, Katherine Luzuriaga, and Mohan Somasundaran), PloS one (2009)
BACKGROUND: Rapid and cost-effective methods for HIV-1 diagnosis and viral load monitoring would greatly enhance...
No subject area
Gene set enrichment analysis for non-monotone association and multiple experimental categories (with Shuangshuang Dai, Richard D. Irwin, Alexandra N. Heinloth, Gary A. Boorman, and Leping Li), BMC Bioinformatics (2008)
Background Recently, microarray data analyses using functional pathway information, e.g., gene set enrichment analysis (GSEA)...