Article
Constitutive and Inducible Expression of the rRNA Methylase Gene erm(B) in Campylobacter
Antimicrobial Agents and Chemotherapy
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
10-1-2015
DOI
10.1128/AAC.01103-15
Abstract
Macrolides are the antimicrobials of choice for treating human campylobacteriosis. The recent emergence of erm(B) in Campylobacter bacteria threatens the utility of this class of antibiotics. Here we report the constitutive and inducible expression of erm(B) in Campylobacter isolates derived from diarrheal patients and food-producing animals. Constitutive expression of erm(B) was associated with insertion and deletion in the regulatory region of the gene, providing the first documentation of the differential expression of erm(B) in Campylobacter bacteria.
Copyright Owner
American Society for Microbiology
Copyright Date
2015
Language
en
File Format
application/pdf
Citation Information
Fengru Deng, Jianzhong Shen, Maojun Zhang, Congming Wu, et al.. "Constitutive and Inducible Expression of the rRNA Methylase Gene erm(B) in Campylobacter" Antimicrobial Agents and Chemotherapy Vol. 59 Iss. 10 (2015) p. 6661 - 6664 Available at: http://works.bepress.com/qijing-zhang/33/
This article is published as Deng, Fengru, Jianzhong Shen, Maojun Zhang, Congming Wu, Qijing Zhang, and Yang Wang. "Constitutive and inducible expression of the rRNA methylase gene erm (B) in Campylobacter." Antimicrobial agents and chemotherapy 59, no. 10 (2015): 6661-6664. doi: 10.1128/AAC.01103-15. Posted with permission.