Articles

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Effect of the HIV-1 fusion peptide on the mechanical properties and leaflet coupling of lipid bilayers (with P. Shchelokovskyy and R. Dimova), Department of Physics (2011)

The fusion peptide (FP) of the human immunodeficiency virus (HIV) is part of the N-terminus...

 

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Effect of cholesterol on structural and mechanical properties of membranes depends on lipid chain saturation (with Jianjun Pan and John F. Nagle), Department of Physics (2009)

The effects of cholesterol on membrane bending modulus KC, membrane thickness DHH, the partial and...

 

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The Effect of Cholesterol on Short- and Long-Chain Monounsaturated Lipid Bilayers as Determined by Molecular Dynamics Simulations and X-Ray Scattering (with Norbert Kucerka, Jason D. Perlmutter, Jianjun Pan, John Katsaras, and Jonathan N. Sachs), Department of Physics (2008)

We investigate the structure of cholesterol-containing membranes composed of either short-chain (diC14:1PC) or long-chain (diC22:1PC)...

 

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Order Parameters and Areas in Fluid-Phase Oriented Lipid Membranes Using Wide Angle X-Ray Scattering (with Thalia T. Mills, Gilman E.S. Toombes, Detlef-M Smilgies, Gerald W. Feigenson, and John F. Nagle), Department of Physics (2008)

We used wide angle x-ray scattering (WAXS) from stacks of oriented lipid bilayers to measure...

 

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Liquid-Liquid Domains in Bilayers Detected by Wide Angle X-Ray Scattering (with Thalia T. Mills, Frederick A. Heberle, Nelson F. Morales, Jiang Zhao, Jing Wu, Gilman E.S. Toombes, John F. Nagle, and Gerald W. Feigenson), Department of Physics (2008)

Wide angle x-ray scattering (WAXS) from oriented lipid multilayers is used to examine liquid-ordered (Lo)/liquiddisordered...

 

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Cholesterol Perturbs Lipid Bilayers Nonuniversally (with Jianjun Pan, Thalia T. Mills, and John F. Nagle), Department of Physics (2008)

Cholesterol is well known to modulate the physical properties of biomembranes. Using modern x-ray scattering...

 

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Structural Determinants of Water Permeability through the Lipid Membrane (with John C. Mathai, John F. Nagle, and Mark L. Zeidel), Department of Physics (2008)

Despite intense study over many years, the mechanisms by which water and small nonelectrolytes cross...

 

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Temperature Dependence of Structure, Bending Rigidity, and Bilayer Interactions of Dioleoylphosphatidylcholine Bilayers (with Jianjun Pan, Norbert Kucerka, and John F. Nagle), Department of Physics (2008)

X-ray diffuse scattering was measured from oriented stacks and unilamellar vesicles of dioleoylphosphatidylcholine lipid bilayers...

 

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Theory of Passive Permeability through Lipid Bilayers (with John F. Nagle, John C. Mathai, and Mark L. Zeidel), Department of Physics (2008)

Recently measured water permeability through bilayers of different lipids is most strongly correlated with the...

 

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HIV-1 Fusion Peptide Decreases Bending Energy and Promotes Curved Fusion Intermediates (with John F. Nagle), Department of Physics (2007)

A crucial step in human immunodeficiency virus (HIV) infection is fusion between the viral envelope...

 

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Closer Look at Structure of Fully Hydrated Fluid Phase DPPC Bilayers (with Norbert Kucerka and John F. Nagle), Department of Physics (2006)

X-ray data are presented for the benchmark dipalmitoylphosphatidylcholine lipid bilayer in the most biologically relevant...

 

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Swelling of phospholipids by monovalent salt (with Horia I. Petrache, Daniel Harries, Norbert Kucerka, John F. Nagle, and V. Adrian Parsegian), Department of Physics (2006)

Critical to biological processes such as membrane fusion and secretion, ion-lipid interactions at the membrane-water...

 

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Anomalous swelling of lipid bilayer stacks is caused by softening of the bending modulus (with Nanjun Chu, Norbert Kucerka, Yufeng Liu, and John F. Nagle), Department of Physics (2005)

Arrays of bilayers of the lipid dimyristoylphosphatidylcholine (DMPC) exhibit anomalous swelling as the temperature decreases...

 

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Structure of Fully Hydrated Fluid Phase DMPC and DLPC Lipid Bilayers Using X-Ray Scattering from Oriented Multilamellar Arrays and from Unilamellar Vesicles (with Norbert Kucerka, Yufeng Liu, Nanjun Chu, Horia I. Petrache, and John F. Nagle), Department of Physics (2005)

Quantitative structures of the fully hydrated fluid phases of dimyristoylphosphatidylcholine (DMPC) and dilauroylphosphatidylcholine (DLPC) were...

 

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Structure and Fluctuations of Charged Phosphatidylserine Bilayers in the Absence of Salt (with Horia I. Petrache, Klaus Gawrisch, Daniel Harries, V. Adrian Parsegian, and John F. Nagle), Department of Physics (2004)

Using x-ray diffraction and NMR spectroscopy, we present structural and material properties of phosphatidylserine (PS)...

 

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Structure of Gel Phase DMPC Determined by X-Ray Diffraction (with Yufeng Liu, Justin Legleiter, and John F. Nagle), Department of Physics (2002)

The structure of fully hydrated gel phase dimyristoylphosphatidylcholine lipid bilayers was obtained at 10°C. Oriented...

 

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Clarification of the ripple phase of lecithin bilayers using fully hydrated, aligned samples (with John Katsaras, Yufeng Liu, R. L. Headrick, E. Fontes, P. C. Mason, and John F. Nagle), Department of Physics (2000)

Aligned samples of lipid bilayers have been fully hydrated from water vapor in a different...

 

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Method for obtaining structure and interactions from oriented lipid bilayers (with Yulia Lyatskaya, Yufeng Liu, John Katsaras, and John F. Nagle), Department of Physics (2000)

Precise calculations are made of the scattering intensity I(q) from an oriented stack of lipid...

 

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Re-analysis of Magic Angle Spinning Nuclear Magnetic Resonance Determination of Interlamellar Waters in Lipid Bilayer Dispersions (with John F. Nagle, Yufeng Liu, Richard M. Epend, and Ruth E. Stark), Department of Physics (1999)

A recent method to obtain the number of water molecules of hydration of multilamellar lipid...

 

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Multiple mechanisms for critical behavior in the biologically relevant phase of lecithin bilayers (with John F. Nagle, Horia I. Petrache, Nikolai Gouliaev, Yufeng Liu, Robert M. Suter, and Klaus Gawrisch), Department of Physics (1998)

Lipid bilayer membranes manifest critical behavior in the lamellar D spacing observed by x-ray and...