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Antimalarial Activity of 2,4-Diaminopyrimidines

J. Morgan, University of Wollongong
R. Haritakul, National Science and Technology Development Agency
P. A. Keller, University of Wollongong

Article comments

This article was originally published as Morgan, J, Haritakul, R & Keller, PA, Antimalarial Activity of 2,4-Diaminopyrimidines, Letters in Drug Design & Discovery, 5(4), 2008, 277-280. Original journal article available here

Abstract

A series of 2,4- and 4,6-diaminopyrimidines were prepared and evaluated for their in vitro antimalarial activity. Of the 12 compounds tested 7 showed reasonable activity with 1 having a sub-micromolar IC50.

Suggested Citation

J. Morgan, R. Haritakul, and P. A. Keller. "Antimalarial Activity of 2,4-Diaminopyrimidines" Faculty of Science - Papers (2008).
Available at: http://works.bepress.com/pkeller/9