General Biostatistics

Meta-Analysis of Family-Based and Case-Control Genetic Association Studies that Use the Same Cases (with Niki L. Dimou, Theodore D. Liakopoulos, and Georgios K. Nikolopoulos), Statistical Applications in Genetics and Molecular Biology (2011)

In many cases in genetic epidemiology, the investigators in an effort to control for different...

 
Mixed-Effects Poisson Regression Models for Meta-Analysis of Follow-Up Studies with Constant or Varying Durations (with Georgios K. Nikolopoulos), The International Journal of Biostatistics (2009)

We present a framework for meta-analysis of follow-up studies with constant or varying duration using...

 
A Unification of Multivariate Methods for Meta-Analysis of Genetic Association Studies, Statistical Applications in Genetics and Molecular Biology (2008)

Methods for multivariate meta-analysis of genetic association studies are reviewed, summarized and presented in a...

 
A Method for Meta-Analysis of Case-Control Genetic Association Studies Using Logistic Regression (with Georgios K. Nikolopoulos), Statistical Applications in Genetics and Molecular Biology (2007)

We propose here a simple and robust approach for meta-analysis of molecular association studies. Making...

 

Epidemiology

Meta-Analysis of Family-Based and Case-Control Genetic Association Studies that Use the Same Cases (with Niki L. Dimou, Theodore D. Liakopoulos, and Georgios K. Nikolopoulos), Statistical Applications in Genetics and Molecular Biology (2011)

In many cases in genetic epidemiology, the investigators in an effort to control for different...

 
Mixed-Effects Poisson Regression Models for Meta-Analysis of Follow-Up Studies with Constant or Varying Durations (with Georgios K. Nikolopoulos), The International Journal of Biostatistics (2009)

We present a framework for meta-analysis of follow-up studies with constant or varying duration using...

 
A Unification of Multivariate Methods for Meta-Analysis of Genetic Association Studies, Statistical Applications in Genetics and Molecular Biology (2008)

Methods for multivariate meta-analysis of genetic association studies are reviewed, summarized and presented in a...

 
A Method for Meta-Analysis of Case-Control Genetic Association Studies Using Logistic Regression (with Georgios K. Nikolopoulos), Statistical Applications in Genetics and Molecular Biology (2007)

We propose here a simple and robust approach for meta-analysis of molecular association studies. Making...

 

Statistical Models

Meta-Analysis of Family-Based and Case-Control Genetic Association Studies that Use the Same Cases (with Niki L. Dimou, Theodore D. Liakopoulos, and Georgios K. Nikolopoulos), Statistical Applications in Genetics and Molecular Biology (2011)

In many cases in genetic epidemiology, the investigators in an effort to control for different...

 
Mixed-Effects Poisson Regression Models for Meta-Analysis of Follow-Up Studies with Constant or Varying Durations (with Georgios K. Nikolopoulos), The International Journal of Biostatistics (2009)

We present a framework for meta-analysis of follow-up studies with constant or varying duration using...

 
A Unification of Multivariate Methods for Meta-Analysis of Genetic Association Studies, Statistical Applications in Genetics and Molecular Biology (2008)

Methods for multivariate meta-analysis of genetic association studies are reviewed, summarized and presented in a...

 
A Method for Meta-Analysis of Case-Control Genetic Association Studies Using Logistic Regression (with Georgios K. Nikolopoulos), Statistical Applications in Genetics and Molecular Biology (2007)

We propose here a simple and robust approach for meta-analysis of molecular association studies. Making...

 

Genetics

Meta-Analysis of Family-Based and Case-Control Genetic Association Studies that Use the Same Cases (with Niki L. Dimou, Theodore D. Liakopoulos, and Georgios K. Nikolopoulos), Statistical Applications in Genetics and Molecular Biology (2011)

In many cases in genetic epidemiology, the investigators in an effort to control for different...

 
A Unification of Multivariate Methods for Meta-Analysis of Genetic Association Studies, Statistical Applications in Genetics and Molecular Biology (2008)

Methods for multivariate meta-analysis of genetic association studies are reviewed, summarized and presented in a...

 

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Cytokine gene polymorphisms in periodontal disease: A meta-analysis of 53 studies including 4178 cases and 4590 controls (with Georgios K. Nikolopoulos, Niki L. Dimou, and Stavros J. Hamodrakas), Journal of Clinical Periodontology (2008)

AIM: We conducted a systematic review and a meta-analysis, in order to investigate the potential...

 
A Method for Meta-Analysis of Case-Control Genetic Association Studies Using Logistic Regression (with Georgios K. Nikolopoulos), Statistical Applications in Genetics and Molecular Biology (2007)

We propose here a simple and robust approach for meta-analysis of molecular association studies. Making...

 

Clinical Epidemiology

Meta-Analysis of Family-Based and Case-Control Genetic Association Studies that Use the Same Cases (with Niki L. Dimou, Theodore D. Liakopoulos, and Georgios K. Nikolopoulos), Statistical Applications in Genetics and Molecular Biology (2011)

In many cases in genetic epidemiology, the investigators in an effort to control for different...

 
Mixed-Effects Poisson Regression Models for Meta-Analysis of Follow-Up Studies with Constant or Varying Durations (with Georgios K. Nikolopoulos), The International Journal of Biostatistics (2009)

We present a framework for meta-analysis of follow-up studies with constant or varying duration using...

 

Multivariate Analysis

Mixed-Effects Poisson Regression Models for Meta-Analysis of Follow-Up Studies with Constant or Varying Durations (with Georgios K. Nikolopoulos), The International Journal of Biostatistics (2009)

We present a framework for meta-analysis of follow-up studies with constant or varying duration using...

 

Bioinformatics

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gpDB: a database of G-proteins, GPCRs, Effectors and their interactions (with Margarita C. Theodoropoulou, Ioannis C. Spyropoulos, and Stavros J. Hamodrakas), Bioinformatics (2008)

SUMMARY: gpDB is a publicly accessible, relational database, containing information about G-proteins, G-protein coupled receptors...

 

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Prediction of cell wall sorting signals in gram-positive bacteria with a hidden markov model: application to complete genomes (with Zoi I. Litou, Konstantinos D. Tsirigos, and Stavros J. Hamodrakas), Journal of Bioinformatics and Computational Biology (2008)

Surface proteins in Gram-positive bacteria are frequently implicated in virulence. We have focused on a...

 

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Algorithms for incorporating prior topological information in HMMs: Application to transmembrane proteins (with Theodore D. Liakopoulos and Stavros J. Hamodrakas), BMC Bioinformatics (2006)

BACKGROUND: Hidden Markov Models (HMMs) have been extensively used in computational molecular biology, for modelling...

 

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PredSL: a tool for the N-terminal sequence-based prediction of protein subcellular localization (with Evangelia I. Petsalaki, Zoi I. Litou, and Stavros J. Hamodrakas), Genomics Proteomics and Bioinformatics (2006)

The ability to predict the subcellular localization of a protein from its sequence is of...

 

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β-barrel Transmembrane Proteins: Geometric Modelling, Detection of Transmembrane Region, and Structural Properties (with Ioannis K. Valavanis and Ioannis Z. Emiris), Computational Biology and Chemistry (2006)

The location of the membrane lipid bilayer relative to a transmembrane protein structure is important...

 

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A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models (with Nikolaos G. Sgourakis, Panagiotis K. Papasaikas, and Stavros J. Hamodrakas), BMC Bioinformatics (2005)

BACKGROUND: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors...

 

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Evaluation of methods for predicting the topology of ß-barrel outer membrane proteins and a consensus prediction method (with Theodore D. Liakopoulos and Stavros J. Hamodrakas), BMC Bioinformatics (2005)

BACKGROUND: Prediction of the transmembrane strands and topology of beta-barrel outer membrane proteins is of...

 

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Prediction of the coupling specificity of GPCRs to four families of G-proteins using hidden Markov models and artificial neural networks (with Nikolaos G. Sgourakis and Stavros J. Hamodrakas), Bioinformatics (2005)

MOTIVATION: G-protein coupled receptors are a major class of eukaryotic cell-surface receptors. A very important...

 

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Topology prediction of β-barrel outer membrane proteins (with Theodore D. Liakopoulos, Vasilis J. Promponas, and Stavros J. Hamodrakas), PINSA (2005)

In this review, we attempt to summarize sequence and structural features of β-barrel transmembrane proteins...

 

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A database for G proteins and their interaction with GPCRs (with Antigoni L. Elefsinioti, Ioannis C. Spyropoulos, and Stavros J. Hamodrakas), BMC Bioinformatics (2004)

BACKGROUND: G protein-coupled receptors (GPCRs) transduce signals from extracellular space into the cell, through their...

 

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A Hidden Markov Model capable of predicting and discriminating β-barrel outer membrane proteins (with Theodore D. Liakopoulos, Ioannis C. Spyropoulos, and Stavros J. Hamodrakas), BMC Bioinformatics (2004)

BACKGROUND: Integral membrane proteins constitute about 20-30% of all proteins in the fully sequenced genomes....

 

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PRED-GPCR: GPCR recognition and family classification server (with Panagiotis K. Papasaikas, Zoi I. Litou, Vasilis J. Promponas, and Stavros J. Hamodrakas), Nucleic Acids Research (2004)

The vast cell-surface receptor family of G-protein coupled receptors (GPCRs) is the focus of both...

 

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PRED-TMBB: A web server for predicting the topology of β-barrel outer membrane proteins (with Theodore D. Liakopoulos, Ioannis c. Spyropoulos, and Stavros J. Hamodrakas), Nucleic Acids Research (2004)

The beta-barrel outer membrane proteins constitute one of the two known structural classes of membrane...

 

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TMRPres2D: high quality visual representation of transmembrane protein models (with Ioannis C. Spyropoulos, Theodore D. Liakopoulos, and Stavros J. Hamodrakas), Bioinformatics (2004)

The 'TransMembrane protein Re-Presentation in 2-Dimensions' (TMRPres2D) tool, automates the creation of uniform, two-dimensional, high...

 

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A novel method for GPCR recognition and family classification, using fingerprints derived from profile Hidden Markov Models (with Panagiotis K. Papasaikas, Zoi I. Litou, and Stavros J. Hamodrakas), SAR QSAR Environ Res (2003)

G-protein coupled receptors (GPCRs) constitute a broad class of cell-surface receptors, including several functionally distinct...

 

Clinical Trials

Mixed-Effects Poisson Regression Models for Meta-Analysis of Follow-Up Studies with Constant or Varying Durations (with Georgios K. Nikolopoulos), The International Journal of Biostatistics (2009)

We present a framework for meta-analysis of follow-up studies with constant or varying duration using...