gpDB: a database of G-proteins, GPCRs, Effectors and their interactions
SUMMARY: gpDB is a publicly accessible, relational database, containing information about G-proteins, G-protein coupled receptors (GPCRs) and effectors, as well as information concerning known interactions between these molecules. The sequences are classified according to a hierarchy of different classes, families and subfamilies based on literature search. The main innovation besides the classification of G-proteins, GPCRs and effectors is the relational model of the database, describing the known coupling specificity of GPCRs to their respective alpha subunits of G-proteins, and also the specific interaction between G-proteins and their effectors, a unique feature not available in any other database.
SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Margarita C. Theodoropoulou, Pantelis G. Bagos, Ioannis C. Spyropoulos, and Stavros J. Hamodrakas. "gpDB: a database of G-proteins, GPCRs, Effectors and their interactions" Bioinformatics 24.12 (2008): 1471-1472.