Qualifications MB BS(1978), PhD (1987), FRACGP (2002), MRCGP (2005) Professor Paul P Glasziou joined Bond University in July, 2010. He was previously the Director of the Centre for Evidence-Based Medicine, and Professor of Evidence-Based Medicine in the department of Primary Care at the University of Oxford, and also continued work as a part-time General Practitioner. His research and teaching interests are in improving medical decision making, including clinical trials, systematic reviews and evidence-based medicine. The author of over 160 peer-reviewed publications, he has applied his skills to such topics as breast and colorectal cancer screening, otitis media, cholesterol lowering, and anticoagulation for atrial fibrillation.
Evidence-Based Medicine
Letter to the editor: Antibiotics and acute otitis media in children (with Chris Del Mar and Maroeska Rovers), The journal of the American medical association (2011)
Extract:
In Reply: Because of space constraints, some analyses we conducted had to be left out...
The rise of cholesterol testing: How much is unnecessary (with Helen Doll, Brian Shine, Jonathan Kay, and Tim James), British journal of general practice (2011)
Background: Laboratory testing has increased dramatically over recent decades, which is a consequence particularly of...
Seventy-five trials and eleven systematic reviews a day: How will we ever keep up? (with Hilda Bastian and Iain Chalmers), PLoS medicine (2010)
Thirty years ago, and a quarter of a century after randomised trials had become widely...
Taking healthcare interventions from trial to practice (with Iain Chalmers, Douglas G. Altman, Hilda Bastian, Isabelle Boutron, Anne Brice, Gro Jamtvedt, Andrew Farmer, Davina Ghersi, Trish Groves, Carl Heneghan, Sophie Hill, Simon Lewin, Susan Michie, Rafael Perera, Valerie Pomeroy, Julie Tilson, Sasha Shepperd, and John W. Williams), BMJ (2010)
Extract:
The results of thousands of trials are never acted on because their published reports...
Reducing the waste in health care research, Presentation at Bond University, Gold Coast, Australia (2010)
Primary-Care Research
What are the basic self-monitoring components for cardiovascular risk management? (with Alison M. Ward, Carl Heneghan, Rafael Perera, Dan Lasserson, David Nunan, and David Mant), BMC medical research methodology (2010)
Background: Self-monitoring is increasingly recommended as a method of managing cardiovascular disease. However, the design,...
Cost-effectiveness of lowering blood pressure with a fixed combination of perindopril and indapamide in type 2 diabetes mellitus: An ADVANCE trial-based analysis (with Philip M. Clarke, Jan Alexander, Mohana Rajmokan, Elaine Beller, Mark Woodward, John Chalmers, Neil Poulter, and Anushka A. Patel), The Medical Journal of Australia (MJA) (2010)
Objective: To determine the cost-effectiveness of routine administration, irrespective of blood pressure (BP), of a...
Using N-of-1 trials to improve patient management and save costs (with Paul A. Scuffham, Jane Nikles, Geoffrey K. Mitchell, Michael J. Yelland, Norma Vine, Christopher J. Poulos, Peter I. Pillans, Guy Bashford, Chris Del Mar, and Philip J. Schluter), Journal of general internal medicine (2010)
BACKGROUND: N-of-1 trials test treatment effectiveness within an individual patient.
OBJECTIVE: To assess (i) the...
Corticosteroids for pain relief in sore throat: Systematic review and meta-analysis (with Gail Hayward, Matthew J. Thompson, Carl J. Heneghan, Rafael Perera, and Chris B. Del Mar), BMJ (2009)
Objective: To evaluate whether systemic corticosteroids improve symptoms of sore throat in adults and children....
Antibiotics for acute otitis media in children (Review) (with Sharon Sanders, Chris Del Mar, and Maroeska Rovers), Cochrane database of systematic reviews (2009)
Background: Acute otitis media (AOM) is one of the most common diseases in early infancy...
Decision Making
The rise of cholesterol testing: How much is unnecessary (with Helen Doll, Brian Shine, Jonathan Kay, and Tim James), British journal of general practice (2011)
Background: Laboratory testing has increased dramatically over recent decades, which is a consequence particularly of...
Clinical thinking: Evidence, communication and decision-making (with Chris Del Mar and Jenny Doust), Health Sciences & Medicine papers (2006)
Clinicians are taught masses of facts, but not how to use them in the messy...
Models of disease (with Chris Del Mar and Jenny Doust), Clinical thinking: evidence, communication, and decision-making (2006)
[Excerpt] What we will do here is set out some models of disease, and then...
Decision making in health and medicine: Integrating evidence and values (with M. G. Myriam Hunink, Joanna E. Siegel, Jane C. Weeks, Joseph S. Pliskin, Arthur S. Elstein, and Milton C. Weinstein) (2001)
Decision making in health care involves navigating through a complex and tangled web of diagnostic...
Randomized Controlled Trials as Topic
Stopping Randomized Trials Early for Benefit: A Protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2) (with Matthias Briel, Melanie Lane, Victor M. Montori, Dirk Bassler, German Malaga, Elie A. Akl, Ignacio Ferreira-Gonzalez, Pablo Alonso-Coello, Gerard Urrutia, Regina Kunz, Carolina Ruiz Culebro, Suzana Alves da Silva, David N. Flynn, Mohamed B. Elamin, Brigitte Strahm, M. Hassan Murad, Benjamin Djulbegovic, Neill K. J. Adhikari, Edward J. Mills, Femida Gwadry-Sridhar, Haresh Kirpalani, Heloisa P. Soares, Nisrin O. Abu Elnour, John J. You, Paul J. Karanicolas, Heiner C. Bucher, Julianna F. Lampropulos, Alain J. Nordmann, Karen E. A. Burns, Sohail M. Mulla, Heike Raatz, Amit Sood, Jagdeep Kaur, Clare R. Bankhead, Rebecca J. Mullan, Kara A. Nerenberg, Per Olav Vandvik, Fernando Coto-Yglesias, Holger Schünemann, Fabio Tuche, Pedro Paulo M. Chrispim, Deborah J. Cook, Kristina Lutz, Christine M. Ribic, Noah Vale, Patricia J. Erwin, Rafael Perera, Qi Zhou, Diane Heels-Ansdell, Tim Ramsay, Stephen D. Walter, and Gordon H. Guyatt), Trials (2009)
Background: Randomized clinical trials (RCTs) stopped early for benefit often receive great attention and affect...
Curriculum
Teaching evidence based medicine should be integrated into current clinical scenarios (with Chris Del Mar and Dan Mayer), BMJ (2004)
The editorial discusses some elements of teaching and learning evidence based medicine. It comments on...
Treatment Outcome
Antibiotics for acute otitis media in children [Review] (with Chris Del Mar, Sharon L. Sanders, and M. Hayem), The Cochrane Database of Systematic Reviews (2004)
Background: Acute otitis media is one of the most common diseases in early infancy and...
Non-antibiotic treatments for sore throat [Protocol] (with D. Francis, Chris Del Mar, and M. Thomas), The Cochrane Database of Systematic Reviews (2004)
This is the protocol for a review. The objective is as follows: 1. To determine...
Health Care Research
A1C to detect diabetes in healthy adults: When should we recheck? (with Osamu Takahashi, Andrew J. Farmer, Takuro Shimbo, and Tsuguya Fukui), Diabetes care (2010)
OBJECTIVE To evaluate the optimal interval for rechecking A1C levels below the diagnostic threshold of...
Lipid re-screening: What is the best measure and interval? (with Osamu Takahashi, Rafael Perera, Takuro Shimbo, Jiro Suwa, Sonoe Hiramatsu, and Tsuguya Fukui), Heart (2010)
Objectives: To estimate the long-term true change variation ("signal") and short-term within-person variation ("noise") of...
No subject area
The scatter of research: Cross sectional comparison of randomised trials and systematic reviews across specialties (with Tammy Hoffmann, Chrissy Erueti, and Sarah Thorning), BMJ (2012)
Objective: To estimate the degree of scatter of reports of randomised trials and systematic reviews,...
Patterns of 'leakage' in the utilisation of clinical guidelines: A systematic review (with Sharon Mickan and Amanda Burls), Postgraduate medical journal (2011)
Background Research: Evidence is insufficient to change physicians’ behaviour. In 1996, Pathman developed a four...
Buteyko breathing for asthma (protocol) (with Thomas G. Campbell and Tammy Hoffmann), Cochrane database of systematic reviews (2011)
This is the protocol for a review and there is no abstract. The objectives are...
Letter to the editor: Treatment of acute otitis media in children (with Chris Del Mar and Maroeska Rovers), New England journal of medicine (2011)
Cardiovascular risk scores do not account for the effect of treatment: A review (with Su May Liew and Jenny Doust), Heart (2011)
Objective To compare the strengths and limitations of cardiovascular risk scores available for clinicians in...