The objective of this paper is to identify demographic, social and behavioural risk factors for HIV infection among men in Zambia. In particular, the role of alcohol, condom use, and number of sex partners is highlighted as being significant in the prevalence of HIV. Multivariate Logistic Regressions were used to analyse the latest cross-sectional population-based demographic health survey for Zambia (2007). The survey included socio-economic variables and HIV serostatus for consenting men (N = 4,434). Risk for HIV was positively related to the wealth status. Men who considered themselves to be at high risk for HIV-positive were most likely to be HIV-positive. Respondents who, along with their sexual partner, were drunk during the last three times they had sexual intercourse, were more likely to be HIV-positive (Adjusted odds ratio (AOR): 1.60; 95% confidence interval (CI): 1.00-2.56). Men with more than two sexual life partners and inconsistent condom use had a higher risk for being HIV-positive (OR: 1.89; 95% CI: 1.45-2.46 and OR: 1.49; 95% CI: 1.10-2.02, respectively). HIV prevention programs in Zambia should focus even more on these behavioural risk factors.