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Article
Dynamic expression and regulation by Fgf8 and Pou2 of the zebrafish LIM-only gene, lmo4
GSBS Student Publications
  • Mary Ellen Lane
  • Alexander Peter Runko, University of Massachusetts Medical School
  • Nicole Marie Roy, University of Massachusetts Medical School
  • Charles G. Sagerstrom, University of Massachusetts Medical School
GSBS Program
Biochemistry & Molecular Pharmacology
Publication Date
2003-10-1
UMMS Affiliation
Graduate School of Biomedical Sciences; Department of Biochemistry and Molecular Pharmacology
Document Type
Article
Abstract

We report the expression of zebrafish lmo4 during the first 48 h of development. Like its murine ortholog, lmo4 is expressed in somitic mesoderm, branchial arches, otic vesicles, and limb (pectoral fin) buds. In addition, however, we report zebrafish lmo4 expression in the developing eye, cardiovascular tissue, and the neural plate and telencephalon. We demonstrate that expression in the rostral hindbrain requires acerebellar (ace/fgf8) and spiel ohne grenzen (spg/pou2) activity.

DOI of Published Version
10.1016/S1567-133X(02)00061-3
Source

Mech Dev. 2002 Dec;119 Suppl 1:S185-9.

Related Resources

Link to article in PubMed

PubMed ID
14516683
Citation Information
Mary Ellen Lane, Alexander Peter Runko, Nicole Marie Roy and Charles G. Sagerstrom. "Dynamic expression and regulation by Fgf8 and Pou2 of the zebrafish LIM-only gene, lmo4" Vol. 119 Suppl 1 (2003) ISSN: 0925-4773 (Print)
Available at: http://works.bepress.com/nicole_roy/5/