Nicholas P. Jewell is Profesor of Biostatistics and Statistics at the University of California, Berkeley. He has held various academic and administrative positions at Berkeley since his arrival in 1981, most notably serving as Vice Provost from 1994 to 2000. He was trained at the University of Edinburgh where he received an Honours degree in Applied Mathematics in 1973 and a PhD in Mathematics in 1976. Immediately following his graduate program he was appointed to a Harkness Fellowship from 1976-1978 which he held at the University of California, Berkeley and at Stanford University. From 1979-1981 he was an Assistant Professor of Statistics at Princeton University. He has also held academic appointments at the University of Edinburgh and at Oxford University.
Categorical Data Analysis
Choice of Monitoring Mechanism for Optimal Nonparametric Functional Estimation for Binary Data (with Mark J. van der Laan and Stephen Shiboski), U.C. Berkeley Division of Biostatistics Working Paper Series (2004)
Optimal designs of dose levels in order to estimate parameters from a model for binary...
Estimation of Treatment Effects in Randomized Trials with Noncompliance and a Dichotomous Outcome (with Mark J. van der Laan and Alan E. Hubbard), U.C. Berkeley Division of Biostatistics Working Paper Series (2004)
We propose a class of estimators of the treatment effect on a dichotomous outcome among...
Some Surprising Results About Covariate Adjustment in Logistic Regression Models (with Laurence D. Robinson), U.C. Berkeley Division of Biostatistics Working Paper Series (1990)
Results from classic linear regression regarding the effect of adjusting for covariates upon the precision...
The Effect of Retrospective Sampling on Binary Regression Models for Clustered Data (with John M. Neuhaus), U.C. Berkeley Division of Biostatistics Working Paper Series (1989)
Recently a great deal of attention has been given to binary regression models for clustered...
Some Comments on Rosner's Multiple Logistic Model for Clustered Data (with John M. Neuhaus and Nicholas P. Jewell), U.C. Berkeley Division of Biostatistics Working Paper Series (1989)
Rosner (1984, Biometrics 41, 1025-1035) proposed a binary regression model for analyzing binary response data...
Clinical Trials
Analyzing Direct Effects in Randomized Trials with Secondary Interventions (with Michael Rosenblum, Mark J. van dr Laan, Stephen Shiboski, Ariane van der Straten, and Nancy Padian) (2007)
The Methods for Improving Reproductive Health in Africa (MIRA) trial is a recently completed randomized...
Estimation of Treatment Effects in Randomized Trials with Noncompliance and a Dichotomous Outcome (with Mark J. van der Laan and Alan E. Hubbard), U.C. Berkeley Division of Biostatistics Working Paper Series (2004)
We propose a class of estimators of the treatment effect on a dichotomous outcome among...
Computation
Bivariate Current Status Data (with Mark J. van der Laan), U.C. Berkeley Division of Biostatistics Working Paper Series (2002)
In many applications, it is often of interest to estimate a bivariate distribution of two...
Maximum Likelihood Estimation of Ordered Multinomial Parameters (with John D. Kalbfleisch), U.C. Berkeley Division of Biostatistics Working Paper Series (2001)
The pool-adjacent violator-algorithm (Ayer, et al., 1955) has long been known to give the maximum...
Variances for Maximum Penalized Likelihood Estimates Obtained via the EM Algorithm (with Mark R. Segal and Peter Bacchetti), U.C. Berkeley Division of Biostatistics Working Paper Series (1992)
We address the problem of providing variances for parameter estimates obtained under a penalized likelihood...
Disease Modeling
Some Variants of the Backcalculation Method for Estimation of Disease Incidence: An Application to Multiple Sclerosis Data from the Faroe Islands (with Biao Wm. Lu), The International Journal of Biostatistics (2006)
Backcalculation is a technique that was originally developed for the study of HIV incidence. Here...
Estimation of the Case Fatality Ratio with Competing Risks Data: An Application to Severe Acute Respiratory Syndome (SARS) (with Xiudong Lei, A. C. Ghani, C. A. Donnelly, G. M. Leung, L. M. Ho, B. Cowling, and A. J. Hedley), U.C. Berkeley Division of Biostatistics Working Paper Series (2005)
For diseases with some level of associated mortality, the case fatality ratio measures the proportion...
Temporal Stability and Geographic Variation in Cumulative Case Fatality Rates and Average Doubling Times of SARS Epidemics (with Alison P. Galvani and Xiudong Lei), U.C. Berkeley Division of Biostatistics Working Paper Series (2003)
We analyze temporal stability and geographic trends in cumulative case fatality rates and average doubling...
Efficient Estimation of the Lifetime and Disease Onset Distribution (with Mark J. van der Laan and Derick R. Peterson), U.C. Berkeley Division of Biostatistics Working Paper Series (1997)
We study efficient nonparametric maximum likelihood estimation of the distribution of onset and lifetime associated...
Backcalculation of Multiple Sclerosis Incidence Rates Based on Faroe Islands Data (with Biao Wm. Lu), U.C. Berkeley Division of Biostatistics Working Paper Series (1996)
To address the controversial hypothesis that multiple sclerosis is infectious, detailed analysis is performed on...
Epidemiology
Analyzing Direct Effects in Randomized Trials with Secondary Interventions (with Michael Rosenblum, Mark J. van dr Laan, Stephen Shiboski, Ariane van der Straten, and Nancy Padian) (2007)
The Methods for Improving Reproductive Health in Africa (MIRA) trial is a recently completed randomized...
Some Variants of the Backcalculation Method for Estimation of Disease Incidence: An Application to Multiple Sclerosis Data from the Faroe Islands (with Biao Wm. Lu), The International Journal of Biostatistics (2006)
Backcalculation is a technique that was originally developed for the study of HIV incidence. Here...
Estimation of the Case Fatality Ratio with Competing Risks Data: An Application to Severe Acute Respiratory Syndome (SARS) (with Xiudong Lei, A. C. Ghani, C. A. Donnelly, G. M. Leung, L. M. Ho, B. Cowling, and A. J. Hedley), U.C. Berkeley Division of Biostatistics Working Paper Series (2005)
For diseases with some level of associated mortality, the case fatality ratio measures the proportion...
Estimation of Treatment Effects in Randomized Trials with Noncompliance and a Dichotomous Outcome (with Mark J. van der Laan and Alan E. Hubbard), U.C. Berkeley Division of Biostatistics Working Paper Series (2004)
We propose a class of estimators of the treatment effect on a dichotomous outcome among...
Temporal Stability and Geographic Variation in Cumulative Case Fatality Rates and Average Doubling Times of SARS Epidemics (with Alison P. Galvani and Xiudong Lei), U.C. Berkeley Division of Biostatistics Working Paper Series (2003)
We analyze temporal stability and geographic trends in cumulative case fatality rates and average doubling...
General Biostatistics
Institutional and Historical
Shaping the Future of Public Health: The Role of Biostatistics, U.C. Berkeley Division of Biostatistics Working Paper Series (1993)
Comments about the current place for the discipline of Biostatistics within Public Health (1993).
Intervention & Safety Trials
Analyzing Direct Effects in Randomized Trials with Secondary Interventions (with Michael Rosenblum, Mark J. van dr Laan, Stephen Shiboski, Ariane van der Straten, and Nancy Padian) (2007)
The Methods for Improving Reproductive Health in Africa (MIRA) trial is a recently completed randomized...
Longitudinal Data Analysis and Time Series
An Annotated Bibliography of Methods for Analyzing Correlated Categorical Data (with Mark Ashby, John M. Neuhaus, Walter W. Hauck, Peter Bacchetti, David C. Heilbron, Mark R. Segal, and Robert E. Fusaro), U.C. Berkeley Division of Biostatistics Working Paper Series (1991)
This paper provides an annotated bibliography of over 100 articles concerning methods for analyzing correlated...
Hypothesis Testing of Regression Parameters in Semi-Parametric Generalized Linear Models for Cluster Correlated Data (with Andrea Rotnitzky), U.C. Berkeley Division of Biostatistics Working Paper Series (1989)
Generalized and "working" Wald and score tests for regression coefficients in the class of semi-parametric...
Statistical Models
Correspondences between Regression Models for Complex Binary Outcomes and Those for Structured Multivariate Survival Analyses, U.C. Berkeley Division of Biostatistics Working Paper Series (2005)
Doksum and Gasko [5] described a one-to-one correspondence between regression models for binary outcomes and...
Estimation of Treatment Effects in Randomized Trials with Noncompliance and a Dichotomous Outcome (with Mark J. van der Laan and Alan E. Hubbard), U.C. Berkeley Division of Biostatistics Working Paper Series (2004)
We propose a class of estimators of the treatment effect on a dichotomous outcome among...
Accelerated Hazards Model: Method, Theory and Applications (with Ying Qing Chen and Jingrong Yang), U.C. Berkeley Division of Biostatistics Working Paper Series (2002)
In an accelerated hazards model, the hazard functions of a failure time are related through...
Inference for Proportional Mean Residual Life Model in the Presence of Censoring (with Ying Q. Chen), U.C. Berkeley Division of Biostatistics Working Paper Series (2002)
As a function of time t, mean residual life is defined as remaining life expectancy...
On a General Class of Semiparametric Hazards Regression Models (with Ying Qing Chen), U.C. Berkeley Division of Biostatistics Working Paper Series (2000)
A general class of semiparametric hazards regression models for survival data is proposed and studied....
Statistical Theory and Methods
Analyzing Direct Effects in Randomized Trials with Secondary Interventions (with Michael Rosenblum, Mark J. van dr Laan, Stephen Shiboski, Ariane van der Straten, and Nancy Padian) (2007)
The Methods for Improving Reproductive Health in Africa (MIRA) trial is a recently completed randomized...
Some Variants of the Backcalculation Method for Estimation of Disease Incidence: An Application to Multiple Sclerosis Data from the Faroe Islands (with Biao Wm. Lu), The International Journal of Biostatistics (2006)
Backcalculation is a technique that was originally developed for the study of HIV incidence. Here...
Correspondences between Regression Models for Complex Binary Outcomes and Those for Structured Multivariate Survival Analyses, U.C. Berkeley Division of Biostatistics Working Paper Series (2005)
Doksum and Gasko [5] described a one-to-one correspondence between regression models for binary outcomes and...
Estimation of the Case Fatality Ratio with Competing Risks Data: An Application to Severe Acute Respiratory Syndome (SARS) (with Xiudong Lei, A. C. Ghani, C. A. Donnelly, G. M. Leung, L. M. Ho, B. Cowling, and A. J. Hedley), U.C. Berkeley Division of Biostatistics Working Paper Series (2005)
For diseases with some level of associated mortality, the case fatality ratio measures the proportion...
Choice of Monitoring Mechanism for Optimal Nonparametric Functional Estimation for Binary Data (with Mark J. van der Laan and Stephen Shiboski), U.C. Berkeley Division of Biostatistics Working Paper Series (2004)
Optimal designs of dose levels in order to estimate parameters from a model for binary...
Survival Analysis
Correspondences between Regression Models for Complex Binary Outcomes and Those for Structured Multivariate Survival Analyses, U.C. Berkeley Division of Biostatistics Working Paper Series (2005)
Doksum and Gasko [5] described a one-to-one correspondence between regression models for binary outcomes and...
Choice of Monitoring Mechanism for Optimal Nonparametric Functional Estimation for Binary Data (with Mark J. van der Laan and Stephen Shiboski), U.C. Berkeley Division of Biostatistics Working Paper Series (2004)
Optimal designs of dose levels in order to estimate parameters from a model for binary...
Accelerated Hazards Model: Method, Theory and Applications (with Ying Qing Chen and Jingrong Yang), U.C. Berkeley Division of Biostatistics Working Paper Series (2002)
In an accelerated hazards model, the hazard functions of a failure time are related through...
Case-Control Current Status Data (with Mark J. van der Laan), U.C. Berkeley Division of Biostatistics Working Paper Series (2002)
Current status observation on survival times has recently been widely studied. An extreme form of...
Bivariate Current Status Data (with Mark J. van der Laan), U.C. Berkeley Division of Biostatistics Working Paper Series (2002)
In many applications, it is often of interest to estimate a bivariate distribution of two...