MAP Kinase Kinase 2

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

MAP Kinase Signaling System

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Gene Expression Regulation, Fungal

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Book Reviews

Polymers

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Kinetics

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Crystallography, X-Ray

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Sequence Alignment

Link

Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs) (with Chittoor P. Swaminathan, Patrick H. Brown, Abhijit Roychowdhury, Qian Wang, Rongjin Guan, William E. Goldman, Geert-Jan Boons, and Roy A. Mariuzza), Proceedings of the National Academy of Sciences of the United States of America (2006)
 

Link

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains (with Shelley L. Berger, Benjamin Pina, Gregory A. Marcus, Julie Agapite, Jeffrey L. Regier, Steven J. Triezenberg, and Leonard Guarente), Cell (1992)
 

Receptors, Scavenger

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Ubiquitin

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Antimicrobial Cationic Peptides

PDF

Specificity and Signaling in the Drosophila Immune Response (with Nicholas Paul Paquette and Kamna Aggarwal), Invertebrate Survival Journal (2009)
 

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Ubiquitin-Conjugating Enzymes

Link

The role of ubiquitination in Drosophila innate immunity (with Rui Zhou, Mei Hong, Dorothy S. Liao, Yvonne Chung, Zhijian J. Chen, and Tom Maniatis), The Journal of biological chemistry (2005)
 

Carcinoma, Basal Cell

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Immunoblotting

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Transcriptional Activation

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Link

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription (with Julie Agapite and Leonard Guarente), Proceedings of the National Academy of Sciences of the United States of America (1994)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Protein Sorting Signals

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Gene Expression Regulation

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

PDF

Fighting infection fly-style (with Louisa Wu), Fly (2007)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Bacterial recognition and signalling by the Drosophila IMD pathway (with Takashi Kaneko), Cellular microbiology (2005)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Promoter Regions, Genetic

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Link

Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein (with Nickolai A. Barlev, Reyes Candau, Lian Wang, Paula Darpino, and Shelley L. Berger), The Journal of biological chemistry (1995)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

inhibitors

PDF

Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway (with Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Erturk Hasdemir, and Nicholas Paquette), PLoS pathogens (2008)
 

Drug Resistance, Microbial

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Phylogeny

Link

NF-kappaB signaling pathways in mammalian and insect innate immunity (with Tom Maniatis), Genes and development (2001)
 

Organ Specificity

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Protein Isoforms

Link

Peptidoglycan recognition by the Drosophila Imd pathway (with Takashi Kaneko and Douglas T. Golenbock), Journal of endotoxin research (2005)
 

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Mitogen-Activated Protein Kinases

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Carrier Proteins

Link

Taming the symbiont for coexistence: a host PGRP neutralizes a bacterial symbiont toxin (with Joshua V. Troll, Eric H. Bent, Nicholas Paul Paquette, Andrew M. Wier, William E. Goldman, and Margaret J. McFall-Ngai), Environmental microbiology (2010)
 

PDF

Specificity and Signaling in the Drosophila Immune Response (with Nicholas Paul Paquette and Kamna Aggarwal), Invertebrate Survival Journal (2009)
 

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Link

Peptidoglycan recognition in Drosophila (with Kamna Aggarwal), Biochemical Society transactions (2007)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs) (with Chittoor P. Swaminathan, Patrick H. Brown, Abhijit Roychowdhury, Qian Wang, Rongjin Guan, William E. Goldman, Geert-Jan Boons, and Roy A. Mariuzza), Proceedings of the National Academy of Sciences of the United States of America (2006)
 

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Gene Deletion

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

*Immunity, Natural

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Skin Diseases

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Viruses

Link

Host-pathogen interactions in drosophila: new tricks from an old friend (with Sara Cherry), Nature immunology (2006)
 

Transfection

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Mitogen-Activated Protein Kinase Kinases

Link

Immune activation of NF-kappaB and JNK requires Drosophila TAK1 (with Rui Zhou, Rachel L. Erlich, Mike Hunter, Erik Bernstein, David S. Schneider, and Tom Maniatis), The Journal of biological chemistry (2003)
 

Bombyx

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Models, Molecular

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Immunity, Natural

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Link

The role of ubiquitination in Drosophila innate immunity (with Rui Zhou, Mei Hong, Dorothy S. Liao, Yvonne Chung, Zhijian J. Chen, and Tom Maniatis), The Journal of biological chemistry (2005)
 

Link

Aging of the innate immune response in Drosophila melanogaster (with Melissa Zerofsky, Ephat Harel, and Marc Tatar), Aging cell (2005)
 

Link

Bacterial recognition and signalling by the Drosophila IMD pathway (with Takashi Kaneko), Cellular microbiology (2005)
 

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Bacterial Proteins

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Link

Peptidoglycan recognition by the Drosophila Imd pathway (with Takashi Kaneko and Douglas T. Golenbock), Journal of endotoxin research (2005)
 

Amino Acid Sequence

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Link

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains (with Shelley L. Berger, Benjamin Pina, Gregory A. Marcus, Julie Agapite, Jeffrey L. Regier, Steven J. Triezenberg, and Leonard Guarente), Cell (1992)
 

Humans

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs) (with Chittoor P. Swaminathan, Patrick H. Brown, Abhijit Roychowdhury, Qian Wang, Rongjin Guan, William E. Goldman, Geert-Jan Boons, and Roy A. Mariuzza), Proceedings of the National Academy of Sciences of the United States of America (2006)
 

Intracellular Fluid

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Recombinant Proteins

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

RNA Interference

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Plasmids

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

RNA Helicases

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Conserved Sequence

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Antigens, CD

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Brazil

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Mice

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Symbiosis

Link

Taming the symbiont for coexistence: a host PGRP neutralizes a bacterial symbiont toxin (with Joshua V. Troll, Eric H. Bent, Nicholas Paul Paquette, Andrew M. Wier, William E. Goldman, and Margaret J. McFall-Ngai), Environmental microbiology (2010)
 

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Genome

Link

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains (with Shelley L. Berger, Benjamin Pina, Gregory A. Marcus, Julie Agapite, Jeffrey L. Regier, Steven J. Triezenberg, and Leonard Guarente), Cell (1992)
 

Interleukin-8

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Trans-Activators

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Link

Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein (with Nickolai A. Barlev, Reyes Candau, Lian Wang, Paula Darpino, and Shelley L. Berger), The Journal of biological chemistry (1995)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Antibiosis

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Membrane Proteins

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Pectobacterium carotovorum

PDF

Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway (with Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Erturk Hasdemir, and Nicholas Paquette), PLoS pathogens (2008)
 

Toll-Like Receptor 7

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

MAP Kinase Kinase Kinases

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Link

Immune activation of NF-kappaB and JNK requires Drosophila TAK1 (with Rui Zhou, Rachel L. Erlich, Mike Hunter, Erik Bernstein, David S. Schneider, and Tom Maniatis), The Journal of biological chemistry (2003)
 

Protein Processing, Post-Translational

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Nitric Oxide Synthase

Link

Flies kNOw how to signal, Developmental cell (2003)
 

*Trans-Activators

Link

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains (with Shelley L. Berger, Benjamin Pina, Gregory A. Marcus, Julie Agapite, Jeffrey L. Regier, Steven J. Triezenberg, and Leonard Guarente), Cell (1992)
 

MAP Kinase Kinase 4

Link

The role of ubiquitination in Drosophila innate immunity (with Rui Zhou, Mei Hong, Dorothy S. Liao, Yvonne Chung, Zhijian J. Chen, and Tom Maniatis), The Journal of biological chemistry (2005)
 

Link

Immune activation of NF-kappaB and JNK requires Drosophila TAK1 (with Rui Zhou, Rachel L. Erlich, Mike Hunter, Erik Bernstein, David S. Schneider, and Tom Maniatis), The Journal of biological chemistry (2003)
 

*Signal Transduction

Link

Bacterial recognition and signalling by the Drosophila IMD pathway (with Takashi Kaneko), Cellular microbiology (2005)
 

Link

Flies kNOw how to signal, Developmental cell (2003)
 

Link

NF-kappaB signaling pathways in mammalian and insect innate immunity (with Tom Maniatis), Genes and development (2001)
 

Transcription Factors

Link

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection (with Iiro Taneli Helenius, Thomas Krupinski, Douglas W. Turnbull, Yosef Gruenbaum, Eric A. Johnson, Peter H. S. Sporn, Jacob I. Sznajder, and Greg J. Beitel), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 
Acetylation, Activation and Toxicity: The Role of ADA/GCN5 Complex in Transcription (with Leonard Guarente), Mechanisms of Transcription (1997)
 

Link

Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein (with Nickolai A. Barlev, Reyes Candau, Lian Wang, Paula Darpino, and Shelley L. Berger), The Journal of biological chemistry (1995)
 

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Link

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription (with Julie Agapite and Leonard Guarente), Proceedings of the National Academy of Sciences of the United States of America (1994)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Microscopy, Fluorescence

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Herpes Simplex Virus Protein Vmw65

Link

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription (with Julie Agapite and Leonard Guarente), Proceedings of the National Academy of Sciences of the United States of America (1994)
 

*Gene Expression Regulation

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Inositol

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Embryo, Nonmammalian

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Hypercapnia

Link

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection (with Iiro Taneli Helenius, Thomas Krupinski, Douglas W. Turnbull, Yosef Gruenbaum, Eric A. Johnson, Peter H. S. Sporn, Jacob I. Sznajder, and Greg J. Beitel), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

*CCAAT-Binding Factor

Link

Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein (with Nickolai A. Barlev, Reyes Candau, Lian Wang, Paula Darpino, and Shelley L. Berger), The Journal of biological chemistry (1995)
 

Saccharomyces cerevisiae

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Link

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription (with Julie Agapite and Leonard Guarente), Proceedings of the National Academy of Sciences of the United States of America (1994)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Link

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains (with Shelley L. Berger, Benjamin Pina, Gregory A. Marcus, Julie Agapite, Jeffrey L. Regier, Steven J. Triezenberg, and Leonard Guarente), Cell (1992)
 

*Drosophila Proteins

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Prostaglandins

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

*JNK Mitogen-Activated Protein Kinases

Link

Immune activation of NF-kappaB and JNK requires Drosophila TAK1 (with Rui Zhou, Rachel L. Erlich, Mike Hunter, Erik Bernstein, David S. Schneider, and Tom Maniatis), The Journal of biological chemistry (2003)
 

Interleukin-1

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Bacteria

Link

Peptidoglycan recognition in Drosophila (with Kamna Aggarwal), Biochemical Society transactions (2007)
 

PDF

Fighting infection fly-style (with Louisa Wu), Fly (2007)
 

Link

Bacterial recognition and signalling by the Drosophila IMD pathway (with Takashi Kaneko), Cellular microbiology (2005)
 

Peptide Fragments

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Gram-Negative Bacteria

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

MAP Kinase Kinase Kinase 5

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Hemolymph

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Substrate Specificity

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Ligands

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs) (with Chittoor P. Swaminathan, Patrick H. Brown, Abhijit Roychowdhury, Qian Wang, Rongjin Guan, William E. Goldman, Geert-Jan Boons, and Roy A. Mariuzza), Proceedings of the National Academy of Sciences of the United States of America (2006)
 

Nuclear Proteins

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Melanoma

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Receptors, Tumor Necrosis Factor

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

TNF Receptor-Associated Factor 2

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Nitric Oxide

Link

Flies kNOw how to signal, Developmental cell (2003)
 

DNA-Binding Proteins

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein (with Nickolai A. Barlev, Reyes Candau, Lian Wang, Paula Darpino, and Shelley L. Berger), The Journal of biological chemistry (1995)
 

Ions

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Drosophila Proteins

Link

NF-kappaB/Rel Proteins and the Humoral Immune Responses of Drosophila melanogaster (with Sandhya Ganesan, Kamna Aggarwal, and Nicholas Paul Paquette), Current topics in microbiology and immunology (2010)
 

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Link

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection (with Iiro Taneli Helenius, Thomas Krupinski, Douglas W. Turnbull, Yosef Gruenbaum, Eric A. Johnson, Peter H. S. Sporn, Jacob I. Sznajder, and Greg J. Beitel), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

PDF

Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway (with Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Erturk Hasdemir, and Nicholas Paquette), PLoS pathogens (2008)
 

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Link

Bug Versus Bug: Humoral Immune Responses in Drosophila melanogaster (with Deniz Erturk Hasdemir, Nicholas Paquette, and Kamna Aggarwal), Innate Immunity of Plants, Animals, and Humans (2007)
 

PDF

Fighting infection fly-style (with Louisa Wu), Fly (2007)
 

Link

Host-pathogen interactions in drosophila: new tricks from an old friend (with Sara Cherry), Nature immunology (2006)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Peptidoglycan recognition by the Drosophila Imd pathway (with Takashi Kaneko and Douglas T. Golenbock), Journal of endotoxin research (2005)
 

Link

Aging of the innate immune response in Drosophila melanogaster (with Melissa Zerofsky, Ephat Harel, and Marc Tatar), Aging cell (2005)
 

Link

Bacterial recognition and signalling by the Drosophila IMD pathway (with Takashi Kaneko), Cellular microbiology (2005)
 

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Link

Immune activation of NF-kappaB and JNK requires Drosophila TAK1 (with Rui Zhou, Rachel L. Erlich, Mike Hunter, Erik Bernstein, David S. Schneider, and Tom Maniatis), The Journal of biological chemistry (2003)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 
Acetylation, Activation and Toxicity: The Role of ADA/GCN5 Complex in Transcription (with Leonard Guarente), Mechanisms of Transcription (1997)
 

Models, Chemical

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

*DNA-Binding Proteins

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Evolution, Molecular

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Link

The role of ubiquitination in Drosophila innate immunity (with Rui Zhou, Mei Hong, Dorothy S. Liao, Yvonne Chung, Zhijian J. Chen, and Tom Maniatis), The Journal of biological chemistry (2005)
 

*Autophagy

Link

Autophagic control of listeria through intracellular innate immune recognition in drosophila (with Tamaki Yano, Shizuka Mita, Hiroko Ohmori, Yoshiteru Oshima, Yukari Fujimoto, Ryu Ueda, Haruhiko Takada, William E. Goldman, Koichi Fukase, Tamotsu Yoshimori, and Shoichiro Kurata), Nature immunology (2008)
 

Protozoan Infections

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Epithelial Cells

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Calorimetry

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Receptors, Tumor Necrosis Factor, Type I

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

TATA-Box Binding Protein

Link

Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein (with Nickolai A. Barlev, Reyes Candau, Lian Wang, Paula Darpino, and Shelley L. Berger), The Journal of biological chemistry (1995)
 

Intestines

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

DNA, Fungal

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

DNA Mutational Analysis

Link

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains (with Shelley L. Berger, Benjamin Pina, Gregory A. Marcus, Julie Agapite, Jeffrey L. Regier, Steven J. Triezenberg, and Leonard Guarente), Cell (1992)
 

MAP Kinase Kinase 1

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Cell Nucleus

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Blotting, Western

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Insects

Link

NF-kappaB signaling pathways in mammalian and insect innate immunity (with Tom Maniatis), Genes and development (2001)
 

Bordetella pertussis

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Cells, Cultured

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Temperature

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Infection

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

Flies kNOw how to signal, Developmental cell (2003)
 

Amino Acid Motifs

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Protein Kinase C

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Macromolecular Substances

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Link

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription (with Julie Agapite and Leonard Guarente), Proceedings of the National Academy of Sciences of the United States of America (1994)
 

Frameshift Mutation

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Epistasis, Genetic

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Decapodiformes

Link

Taming the symbiont for coexistence: a host PGRP neutralizes a bacterial symbiont toxin (with Joshua V. Troll, Eric H. Bent, Nicholas Paul Paquette, Andrew M. Wier, William E. Goldman, and Margaret J. McFall-Ngai), Environmental microbiology (2010)
 

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Gluconobacter

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Protein-Serine-Threonine Kinases

Link

Immune activation of NF-kappaB and JNK requires Drosophila TAK1 (with Rui Zhou, Rachel L. Erlich, Mike Hunter, Erik Bernstein, David S. Schneider, and Tom Maniatis), The Journal of biological chemistry (2003)
 

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

p38 Mitogen-Activated Protein Kinases

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Peptidoglycan

Link

Taming the symbiont for coexistence: a host PGRP neutralizes a bacterial symbiont toxin (with Joshua V. Troll, Eric H. Bent, Nicholas Paul Paquette, Andrew M. Wier, William E. Goldman, and Margaret J. McFall-Ngai), Environmental microbiology (2010)
 

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

PDF

Specificity and Signaling in the Drosophila Immune Response (with Nicholas Paul Paquette and Kamna Aggarwal), Invertebrate Survival Journal (2009)
 

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Link

Autophagic control of listeria through intracellular innate immune recognition in drosophila (with Tamaki Yano, Shizuka Mita, Hiroko Ohmori, Yoshiteru Oshima, Yukari Fujimoto, Ryu Ueda, Haruhiko Takada, William E. Goldman, Koichi Fukase, Tamotsu Yoshimori, and Shoichiro Kurata), Nature immunology (2008)
 

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Link

Peptidoglycan recognition in Drosophila (with Kamna Aggarwal), Biochemical Society transactions (2007)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs) (with Chittoor P. Swaminathan, Patrick H. Brown, Abhijit Roychowdhury, Qian Wang, Rongjin Guan, William E. Goldman, Geert-Jan Boons, and Roy A. Mariuzza), Proceedings of the National Academy of Sciences of the United States of America (2006)
 

Link

Peptidoglycan recognition by the Drosophila Imd pathway (with Takashi Kaneko and Douglas T. Golenbock), Journal of endotoxin research (2005)
 

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Cell Fractionation

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Apoptosis

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Ecdysterone

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

RNA, Double-Stranded

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Proteins

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Phosphoproteins

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Malpighian Tubules

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

I-kappa B Kinase

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Link

The role of ubiquitination in Drosophila innate immunity (with Rui Zhou, Mei Hong, Dorothy S. Liao, Yvonne Chung, Zhijian J. Chen, and Tom Maniatis), The Journal of biological chemistry (2005)
 

Link

Immune activation of NF-kappaB and JNK requires Drosophila TAK1 (with Rui Zhou, Rachel L. Erlich, Mike Hunter, Erik Bernstein, David S. Schneider, and Tom Maniatis), The Journal of biological chemistry (2003)
 

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Chloramphenicol O-Acetyltransferase

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Toll-Like Receptor 4

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Antiprotozoal Agents

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Recombinant Fusion Proteins

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription (with Julie Agapite and Leonard Guarente), Proceedings of the National Academy of Sciences of the United States of America (1994)
 

beta-Galactosidase

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Immunity, Cellular

PDF

Fighting infection fly-style (with Louisa Wu), Fly (2007)
 

Chromosome Mapping

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

*Saccharomyces cerevisiae Proteins

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein (with Nickolai A. Barlev, Reyes Candau, Lian Wang, Paula Darpino, and Shelley L. Berger), The Journal of biological chemistry (1995)
 

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Link

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription (with Julie Agapite and Leonard Guarente), Proceedings of the National Academy of Sciences of the United States of America (1994)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

*Anti-Infective Agents

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Escherichia coli

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Link

Aging of the innate immune response in Drosophila melanogaster (with Melissa Zerofsky, Ephat Harel, and Marc Tatar), Aging cell (2005)
 

Protein Binding

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs) (with Chittoor P. Swaminathan, Patrick H. Brown, Abhijit Roychowdhury, Qian Wang, Rongjin Guan, William E. Goldman, Geert-Jan Boons, and Roy A. Mariuzza), Proceedings of the National Academy of Sciences of the United States of America (2006)
 

Link

Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein (with Nickolai A. Barlev, Reyes Candau, Lian Wang, Paula Darpino, and Shelley L. Berger), The Journal of biological chemistry (1995)
 

Link

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription (with Julie Agapite and Leonard Guarente), Proceedings of the National Academy of Sciences of the United States of America (1994)
 

Gram-Negative Bacterial Infections

Link

The role of ubiquitination in Drosophila innate immunity (with Rui Zhou, Mei Hong, Dorothy S. Liao, Yvonne Chung, Zhijian J. Chen, and Tom Maniatis), The Journal of biological chemistry (2005)
 

Receptors, Cell Surface

PDF

Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway (with Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Erturk Hasdemir, and Nicholas Paquette), PLoS pathogens (2008)
 

Link

Bacterial recognition and signalling by the Drosophila IMD pathway (with Takashi Kaneko), Cellular microbiology (2005)
 

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Sodium Chloride

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Peptides

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Fat Body

Link

Flies kNOw how to signal, Developmental cell (2003)
 

Antineoplastic Agents

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

*Receptors, Cell Surface

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Protein Kinases

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein (with Nickolai A. Barlev, Reyes Candau, Lian Wang, Paula Darpino, and Shelley L. Berger), The Journal of biological chemistry (1995)
 

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Methoprene

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Ultraviolet Rays

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Acetobacteraceae

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

*Genes, Fungal

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Link

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains (with Shelley L. Berger, Benjamin Pina, Gregory A. Marcus, Julie Agapite, Jeffrey L. Regier, Steven J. Triezenberg, and Leonard Guarente), Cell (1992)
 

Female

Link

Aging of the innate immune response in Drosophila melanogaster (with Melissa Zerofsky, Ephat Harel, and Marc Tatar), Aging cell (2005)
 

Virulence Factors, Bordetella

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs) (with Chittoor P. Swaminathan, Patrick H. Brown, Abhijit Roychowdhury, Qian Wang, Rongjin Guan, William E. Goldman, Geert-Jan Boons, and Roy A. Mariuzza), Proceedings of the National Academy of Sciences of the United States of America (2006)
 

Mutation

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Promoter Regions (Genetics)

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Protein Subunits

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Pulmonary Disease, Chronic Obstructive

Link

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection (with Iiro Taneli Helenius, Thomas Krupinski, Douglas W. Turnbull, Yosef Gruenbaum, Eric A. Johnson, Peter H. S. Sporn, Jacob I. Sznajder, and Greg J. Beitel), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

MAP Kinase Kinase 3

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Molecular Sequence Data

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Link

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains (with Shelley L. Berger, Benjamin Pina, Gregory A. Marcus, Julie Agapite, Jeffrey L. Regier, Steven J. Triezenberg, and Leonard Guarente), Cell (1992)
 

Adaptor Proteins, Signal Transducing

PDF

Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway (with Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Erturk Hasdemir, and Nicholas Paquette), PLoS pathogens (2008)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Serratia marcescens

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Down-Regulation

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Arginine

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Diaminopimelic Acid

Link

Autophagic control of listeria through intracellular innate immune recognition in drosophila (with Tamaki Yano, Shizuka Mita, Hiroko Ohmori, Yoshiteru Oshima, Yukari Fujimoto, Ryu Ueda, Haruhiko Takada, William E. Goldman, Koichi Fukase, Tamotsu Yoshimori, and Shoichiro Kurata), Nature immunology (2008)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Antigens, Bacterial

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Sequence Homology, Amino Acid

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Aminoquinolines

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Cell Membrane

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Base Sequence

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Link

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains (with Shelley L. Berger, Benjamin Pina, Gregory A. Marcus, Julie Agapite, Jeffrey L. Regier, Steven J. Triezenberg, and Leonard Guarente), Cell (1992)
 

TNF Receptor-Associated Factor 3

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Lipopolysaccharides

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Protein Structure, Tertiary

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Mutagenesis

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

*TATA Box

Link

Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein (with Nickolai A. Barlev, Reyes Candau, Lian Wang, Paula Darpino, and Shelley L. Berger), The Journal of biological chemistry (1995)
 

Listeria

Link

Autophagic control of listeria through intracellular innate immune recognition in drosophila (with Tamaki Yano, Shizuka Mita, Hiroko Ohmori, Yoshiteru Oshima, Yukari Fujimoto, Ryu Ueda, Haruhiko Takada, William E. Goldman, Koichi Fukase, Tamotsu Yoshimori, and Shoichiro Kurata), Nature immunology (2008)
 

Models, Biological

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Homeodomain Proteins

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Polymerase Chain Reaction

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Animals

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

PDF

Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway (with Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Erturk Hasdemir, and Nicholas Paquette), PLoS pathogens (2008)
 

Link

Autophagic control of listeria through intracellular innate immune recognition in drosophila (with Tamaki Yano, Shizuka Mita, Hiroko Ohmori, Yoshiteru Oshima, Yukari Fujimoto, Ryu Ueda, Haruhiko Takada, William E. Goldman, Koichi Fukase, Tamotsu Yoshimori, and Shoichiro Kurata), Nature immunology (2008)
 

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Link

Peptidoglycan recognition in Drosophila (with Kamna Aggarwal), Biochemical Society transactions (2007)
 

PDF

Fighting infection fly-style (with Louisa Wu), Fly (2007)
 

Link

Host-pathogen interactions in drosophila: new tricks from an old friend (with Sara Cherry), Nature immunology (2006)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs) (with Chittoor P. Swaminathan, Patrick H. Brown, Abhijit Roychowdhury, Qian Wang, Rongjin Guan, William E. Goldman, Geert-Jan Boons, and Roy A. Mariuzza), Proceedings of the National Academy of Sciences of the United States of America (2006)
 

Link

Peptidoglycan recognition by the Drosophila Imd pathway (with Takashi Kaneko and Douglas T. Golenbock), Journal of endotoxin research (2005)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Link

The role of ubiquitination in Drosophila innate immunity (with Rui Zhou, Mei Hong, Dorothy S. Liao, Yvonne Chung, Zhijian J. Chen, and Tom Maniatis), The Journal of biological chemistry (2005)
 

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Link

Aging of the innate immune response in Drosophila melanogaster (with Melissa Zerofsky, Ephat Harel, and Marc Tatar), Aging cell (2005)
 

Link

Bacterial recognition and signalling by the Drosophila IMD pathway (with Takashi Kaneko), Cellular microbiology (2005)
 

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Link

Immune activation of NF-kappaB and JNK requires Drosophila TAK1 (with Rui Zhou, Rachel L. Erlich, Mike Hunter, Erik Bernstein, David S. Schneider, and Tom Maniatis), The Journal of biological chemistry (2003)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Link

Flies kNOw how to signal, Developmental cell (2003)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

NF-kappaB signaling pathways in mammalian and insect innate immunity (with Tom Maniatis), Genes and development (2001)
 

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Histones

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Receptors, Steroid

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Serine

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Dimerization

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Cell Culture Techniques

Link

The role of ubiquitination in Drosophila innate immunity (with Rui Zhou, Mei Hong, Dorothy S. Liao, Yvonne Chung, Zhijian J. Chen, and Tom Maniatis), The Journal of biological chemistry (2005)
 

Intracellular Signaling Peptides and Proteins

Link

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling (with Nicholas Paul Paquette, Meike Broemer, Kamna Aggarwal, Li Chen, Marie Husson, Deniz Erturk Hasdemir, Jean-Marc Reichhart, and Pascal Meier), Infectious Diseases and Immunology Publications and Presentations (2010)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Genetic Complementation Test

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Immunity, Innate

Link

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling (with Nicholas Paul Paquette, Meike Broemer, Kamna Aggarwal, Li Chen, Marie Husson, Deniz Erturk Hasdemir, Jean-Marc Reichhart, and Pascal Meier), Infectious Diseases and Immunology Publications and Presentations (2010)
 

Link

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection (with Iiro Taneli Helenius, Thomas Krupinski, Douglas W. Turnbull, Yosef Gruenbaum, Eric A. Johnson, Peter H. S. Sporn, Jacob I. Sznajder, and Greg J. Beitel), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

PDF

Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway (with Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Erturk Hasdemir, and Nicholas Paquette), PLoS pathogens (2008)
 

Link

Autophagic control of listeria through intracellular innate immune recognition in drosophila (with Tamaki Yano, Shizuka Mita, Hiroko Ohmori, Yoshiteru Oshima, Yukari Fujimoto, Ryu Ueda, Haruhiko Takada, William E. Goldman, Koichi Fukase, Tamotsu Yoshimori, and Shoichiro Kurata), Nature immunology (2008)
 

Link

Bug Versus Bug: Humoral Immune Responses in Drosophila melanogaster (with Deniz Erturk Hasdemir, Nicholas Paquette, and Kamna Aggarwal), Innate Immunity of Plants, Animals, and Humans (2007)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Juvenile Hormones

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

DNA Primers

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Cloning, Molecular

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

TNF Receptor-Associated Factor 6

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Drosophila

Link

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling (with Nicholas Paul Paquette, Meike Broemer, Kamna Aggarwal, Li Chen, Marie Husson, Deniz Erturk Hasdemir, Jean-Marc Reichhart, and Pascal Meier), Infectious Diseases and Immunology Publications and Presentations (2010)
 

PDF

Specificity and Signaling in the Drosophila Immune Response (with Nicholas Paul Paquette and Kamna Aggarwal), Invertebrate Survival Journal (2009)
 

Link

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection (with Iiro Taneli Helenius, Thomas Krupinski, Douglas W. Turnbull, Yosef Gruenbaum, Eric A. Johnson, Peter H. S. Sporn, Jacob I. Sznajder, and Greg J. Beitel), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Link

Autophagic control of listeria through intracellular innate immune recognition in drosophila (with Tamaki Yano, Shizuka Mita, Hiroko Ohmori, Yoshiteru Oshima, Yukari Fujimoto, Ryu Ueda, Haruhiko Takada, William E. Goldman, Koichi Fukase, Tamotsu Yoshimori, and Shoichiro Kurata), Nature immunology (2008)
 

Link

Peptidoglycan recognition in Drosophila (with Kamna Aggarwal), Biochemical Society transactions (2007)
 

Link

Host-pathogen interactions in drosophila: new tricks from an old friend (with Sara Cherry), Nature immunology (2006)
 

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs) (with Chittoor P. Swaminathan, Patrick H. Brown, Abhijit Roychowdhury, Qian Wang, Rongjin Guan, William E. Goldman, Geert-Jan Boons, and Roy A. Mariuzza), Proceedings of the National Academy of Sciences of the United States of America (2006)
 

Link

Peptidoglycan recognition by the Drosophila Imd pathway (with Takashi Kaneko and Douglas T. Golenbock), Journal of endotoxin research (2005)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Link

The role of ubiquitination in Drosophila innate immunity (with Rui Zhou, Mei Hong, Dorothy S. Liao, Yvonne Chung, Zhijian J. Chen, and Tom Maniatis), The Journal of biological chemistry (2005)
 

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Link

Bacterial recognition and signalling by the Drosophila IMD pathway (with Takashi Kaneko), Cellular microbiology (2005)
 

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Link

Immune activation of NF-kappaB and JNK requires Drosophila TAK1 (with Rui Zhou, Rachel L. Erlich, Mike Hunter, Erik Bernstein, David S. Schneider, and Tom Maniatis), The Journal of biological chemistry (2003)
 

Link

Flies kNOw how to signal, Developmental cell (2003)
 

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Toll-Like Receptors

Link

NF-kappaB/Rel Proteins and the Humoral Immune Responses of Drosophila melanogaster (with Sandhya Ganesan, Kamna Aggarwal, and Nicholas Paul Paquette), Current topics in microbiology and immunology (2010)
 

Link

Autophagic control of listeria through intracellular innate immune recognition in drosophila (with Tamaki Yano, Shizuka Mita, Hiroko Ohmori, Yoshiteru Oshima, Yukari Fujimoto, Ryu Ueda, Haruhiko Takada, William E. Goldman, Koichi Fukase, Tamotsu Yoshimori, and Shoichiro Kurata), Nature immunology (2008)
 

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Link

Bug Versus Bug: Humoral Immune Responses in Drosophila melanogaster (with Deniz Erturk Hasdemir, Nicholas Paquette, and Kamna Aggarwal), Innate Immunity of Plants, Animals, and Humans (2007)
 

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

Bacterial recognition and signalling by the Drosophila IMD pathway (with Takashi Kaneko), Cellular microbiology (2005)
 

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Bacterial Infections

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Molecular Structure

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Skin Neoplasms

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Anti-Infective Agents

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Phosphorylation

Link

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes (with Deniz Erturk Hasdemir, Meike Broemer, Francois Leulier, William S. Lane, Nicholas Paquette, Daye Hwang, Chan-Hee Kim, Svenja Stoven, and Pascal Meier), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Germ-Free Life

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Transcription, Genetic

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Link

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription (with Julie Agapite and Leonard Guarente), Proceedings of the National Academy of Sciences of the United States of America (1994)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Histone Acetyltransferases

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 
Acetylation, Activation and Toxicity: The Role of ADA/GCN5 Complex in Transcription (with Leonard Guarente), Mechanisms of Transcription (1997)
 

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Tumor Necrosis Factor Receptor-Associated Peptides and

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Drosophila melanogaster

Link

NF-kappaB/Rel Proteins and the Humoral Immune Responses of Drosophila melanogaster (with Sandhya Ganesan, Kamna Aggarwal, and Nicholas Paul Paquette), Current topics in microbiology and immunology (2010)
 

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

PDF

Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway (with Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Erturk Hasdemir, and Nicholas Paquette), PLoS pathogens (2008)
 

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Link

Bug Versus Bug: Humoral Immune Responses in Drosophila melanogaster (with Deniz Erturk Hasdemir, Nicholas Paquette, and Kamna Aggarwal), Innate Immunity of Plants, Animals, and Humans (2007)
 

PDF

Fighting infection fly-style (with Louisa Wu), Fly (2007)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Aging of the innate immune response in Drosophila melanogaster (with Melissa Zerofsky, Ephat Harel, and Marc Tatar), Aging cell (2005)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Toll-Like Receptor 3

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Genes, Insect

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Active Transport, Cell Nucleus

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Protein Structure, Secondary

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

*Immunity, Innate

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Cell Wall

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Condylomata Acuminata

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Phenotype

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Colony Count, Microbial

Link

Immunology. The right resident bugs (with Nicholas Paquette), Science (New York, N.Y.) (2008)
 

Microarray Analysis

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Radiation Chimera

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Membrane Glycoproteins

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Protein Conformation

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Sequence Deletion

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Caspases

Link

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling (with Nicholas Paul Paquette, Meike Broemer, Kamna Aggarwal, Li Chen, Marie Husson, Deniz Erturk Hasdemir, Jean-Marc Reichhart, and Pascal Meier), Infectious Diseases and Immunology Publications and Presentations (2010)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

*Symbiosis

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Fungal Proteins

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Link

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription (with Gregory A. Marcus, Junjiro Horiuchi, and Leonard Guarente), Molecular and cellular biology (1996)
 

Link

Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein (with Nickolai A. Barlev, Reyes Candau, Lian Wang, Paula Darpino, and Shelley L. Berger), The Journal of biological chemistry (1995)
 

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Link

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription (with Julie Agapite and Leonard Guarente), Proceedings of the National Academy of Sciences of the United States of America (1994)
 

Link

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors (with Gregory A. Marcus, Shelley L. Berger, Junjiro Horiuchi, and Leonard Guarente), The EMBO journal (1994)
 

Link

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2 (with Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Julie Agapite, and Leonard Guarente), Molecular and cellular biology (1993)
 

Gene Silencing

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Models, Immunological

Link

Peptidoglycan recognition in Drosophila (with Kamna Aggarwal), Biochemical Society transactions (2007)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Sequence Analysis, DNA

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

Micrococcus luteus

Link

Aging of the innate immune response in Drosophila melanogaster (with Melissa Zerofsky, Ephat Harel, and Marc Tatar), Aging cell (2005)
 

Lipid A

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Protein Biosynthesis

Link

ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex (with Junjiro Horiuchi, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1995)
 

Macrophages

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Interferon Regulatory Factor-3

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Genes, Reporter

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Link

Peptidoglycan recognition by the Drosophila Imd pathway (with Takashi Kaneko and Douglas T. Golenbock), Journal of endotoxin research (2005)
 

Link

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish (with Svenja Stoven, Anna Junell, Marika Hedengren-Olcott, Deniz Erturk Hasdemir, Ylva Engstrom, Tom Maniatis, and Dan Hultmark), Proceedings of the National Academy of Sciences of the United States of America (2003)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

effects

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

*Phagocytosis

Link

Host-pathogen interactions in drosophila: new tricks from an old friend (with Sara Cherry), Nature immunology (2006)
 

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Wounds and Injuries

PDF

Fighting infection fly-style (with Louisa Wu), Fly (2007)
 

Cell Line

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Vibrio fischeri

Link

Taming the symbiont for coexistence: a host PGRP neutralizes a bacterial symbiont toxin (with Joshua V. Troll, Eric H. Bent, Nicholas Paul Paquette, Andrew M. Wier, William E. Goldman, and Margaret J. McFall-Ngai), Environmental microbiology (2010)
 

Link

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis (with Joshua V. Troll, Dawn M. Adin, Andrew M. Wier, Nicholas Paquette, William E. Goldman, Frank J. Stadermann, Eric V. Stabb, and Margaret J. McFall-Ngai), Cellular microbiology (2009)
 

Aging

Link

Aging of the innate immune response in Drosophila melanogaster (with Melissa Zerofsky, Ephat Harel, and Marc Tatar), Aging cell (2005)
 

Signal Transduction

Link

NF-kappaB/Rel Proteins and the Humoral Immune Responses of Drosophila melanogaster (with Sandhya Ganesan, Kamna Aggarwal, and Nicholas Paul Paquette), Current topics in microbiology and immunology (2010)
 

Link

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling (with Nicholas Paul Paquette, Meike Broemer, Kamna Aggarwal, Li Chen, Marie Husson, Deniz Erturk Hasdemir, Jean-Marc Reichhart, and Pascal Meier), Infectious Diseases and Immunology Publications and Presentations (2010)
 

PDF

Specificity and Signaling in the Drosophila Immune Response (with Nicholas Paul Paquette and Kamna Aggarwal), Invertebrate Survival Journal (2009)
 

PDF

Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway (with Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Erturk Hasdemir, and Nicholas Paquette), PLoS pathogens (2008)
 

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Link

Peptidoglycan recognition in Drosophila (with Kamna Aggarwal), Biochemical Society transactions (2007)
 

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

PDF

Fighting infection fly-style (with Louisa Wu), Fly (2007)
 

Link

Host-pathogen interactions in drosophila: new tricks from an old friend (with Sara Cherry), Nature immunology (2006)
 

Link

TOLLing away in Brazil (with Jane A. Mitchell, Katherine A. Fitzgerald, Anthony J. Coyle, and Neil Cartwright), Nature immunology (2006)
 

Link

PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan (with Takashi Kaneko, Tamaki Yano, Kamna Aggarwal, Jae-Hong Lim, Kazunori Ueda, Yoshiteru Oshima, Camilla Peach, Deniz Erturk Hasdemir, William E. Goldman, Byung-Ha Oh, and Shoichiro Kurata), Nature immunology (2006)
 

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Link

Peptidoglycan recognition by the Drosophila Imd pathway (with Takashi Kaneko and Douglas T. Golenbock), Journal of endotoxin research (2005)
 

Link

The role of ubiquitination in Drosophila innate immunity (with Rui Zhou, Mei Hong, Dorothy S. Liao, Yvonne Chung, Zhijian J. Chen, and Tom Maniatis), The Journal of biological chemistry (2005)
 

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Heat

Link

Regulation of Drosophila p38 activation by specific MAP2 kinase and MAP3 kinase in response to different stimuli (with Zi-Heng Zhuang, Yuan Zhou, Ming-Can Yu, and Bao-Xue Ge), Cellular signalling (2005)
 

NF-kappa B

Link

NF-kappaB/Rel Proteins and the Humoral Immune Responses of Drosophila melanogaster (with Sandhya Ganesan, Kamna Aggarwal, and Nicholas Paul Paquette), Current topics in microbiology and immunology (2010)
 

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Link

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection (with Iiro Taneli Helenius, Thomas Krupinski, Douglas W. Turnbull, Yosef Gruenbaum, Eric A. Johnson, Peter H. S. Sporn, Jacob I. Sznajder, and Greg J. Beitel), Proceedings of the National Academy of Sciences of the United States of America (2009)
 

Link

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction (with Charles R. Sweet, Joseph E. Conlon, Douglas T. Golenbock, and Jon D. Goguen), Cellular microbiology (2007)
 

Link

DUBbing down innate immunity (with Katherine A. Fitzgerald), Nature immunology (2004)
 

Link

Immune activation of NF-kappaB and JNK requires Drosophila TAK1 (with Rui Zhou, Rachel L. Erlich, Mike Hunter, Erik Bernstein, David S. Schneider, and Tom Maniatis), The Journal of biological chemistry (2003)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

NF-kappaB signaling pathways in mammalian and insect innate immunity (with Tom Maniatis), Genes and development (2001)
 

Insect Proteins

Link

Eater: a big bite into phagocytosis (with Deniz Erturk Hasdemir), Cell (2005)
 

Link

Aging of the innate immune response in Drosophila melanogaster (with Melissa Zerofsky, Ephat Harel, and Marc Tatar), Aging cell (2005)
 

Link

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway (with Antonia Avila, Maria T. Diaz-Meco, and Jorge Moscat), Molecular and cellular biology (2002)
 

Link

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response (with Sophie Rutschmann, Alain C. Jung, Rui Zhou, Jules A. Hoffmann, and Dominique Ferrandon), Nature immunology (2001)
 

Link

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity (with Rui Zhou, Svenja Stoven, Niranjan Pandey, Dan Hultmark, and Tom Maniatis), Genes and development (2000)
 

Blotting, Northern

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Link

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway (with Takashi Kaneko, William E. Goldman, Peter Mellroth, Hakan Steiner, Koichi Fukase, Shoichi Kusumoto, William Harley, Alvin Fox, and Douglas T. Golenbock), Immunity (2004)
 

Lysine

Link

Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins (with Jae-Hong Lim, Min-Sung Kim, Han-Eol Kim, Tamaki Yano, Yoshiteru Oshima, Kamna Aggarwal, William E. Goldman, Shoichiro Kurata, and Byung-Ha Oh), The Journal of biological chemistry (2006)
 

Immune System

Link

Positive and negative regulation of the Drosophila immune response (with Kamna Aggarwal), BMB reports (2008)
 

Cell Proliferation

PDF

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster (with Thomas Flatt, Andreas Heyland, Florentina Rus, Ermelinda Porpiglia, Chris Sherlock, Rochele Yamamoto, Alina Garbuzov, Subba R. Palli, and Marc Tatar), The Journal of experimental biology (2008)
 

Luciferases

Link

Peptidoglycan recognition by the Drosophila Imd pathway (with Takashi Kaneko and Douglas T. Golenbock), Journal of endotoxin research (2005)
 

Acetylation

Link

ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3 (with Junjiro Horiuchi, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente), Molecular and cellular biology (1997)
 

DNA Cleavage

Link

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling (with Nicholas Paul Paquette, Meike Broemer, Kamna Aggarwal, Li Chen, Marie Husson, Deniz Erturk Hasdemir, Jean-Marc Reichhart, and Pascal Meier), Infectious Diseases and Immunology Publications and Presentations (2010)
 

Actinobacillus actinomycetemcomitans

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Ubiquitination

Link

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling (with Nicholas Paul Paquette, Meike Broemer, Kamna Aggarwal, Li Chen, Marie Husson, Deniz Erturk Hasdemir, Jean-Marc Reichhart, and Pascal Meier), Infectious Diseases and Immunology Publications and Presentations (2010)
 

Morphogenesis

Link

Taming the symbiont for coexistence: a host PGRP neutralizes a bacterial symbiont toxin (with Joshua V. Troll, Eric H. Bent, Nicholas Paul Paquette, Andrew M. Wier, William E. Goldman, and Margaret J. McFall-Ngai), Environmental microbiology (2010)
 

Nod1 Signaling Adaptor Protein

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Immunity

PDF

Specificity and Signaling in the Drosophila Immune Response (with Nicholas Paul Paquette and Kamna Aggarwal), Invertebrate Survival Journal (2009)
 

Inhibitor of Apoptosis Proteins

Link

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling (with Nicholas Paul Paquette, Meike Broemer, Kamna Aggarwal, Li Chen, Marie Husson, Deniz Erturk Hasdemir, Jean-Marc Reichhart, and Pascal Meier), Infectious Diseases and Immunology Publications and Presentations (2010)
 

Immune Evasion

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Porphyromonas gingivalis

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Kidney

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Chronic Periodontitis

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Nod2 Signaling Adaptor Protein

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Fusobacterium nucleatum

Link

NOD1 and NOD2 mediate sensing of periodontal pathogens (with T. Okugawa, Takashi Kaneko, A. Yoshimura, and Y. Hara), Journal of dental research (2009)
 

Mice, Knockout

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Tumor Necrosis Factor-alpha

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Reverse Transcriptase Polymerase Chain Reaction

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Mice, Inbred C57BL

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Microscopy, Confocal

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Membrane Transport Proteins

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Toll-Like Receptor 6

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Acetylmuramyl-Alanyl-Isoglutamine

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Host-Pathogen Interactions

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Staphylococcus aureus

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Symporters

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Phagosomes

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Toll-Like Receptor 2

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Green Fluorescent Proteins

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Interleukin-6

Link

Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters (with Guillaume M. Charriere, Wk Eddie Ip, Stephanie Dejardin, Laurent Boyer, Anna Sokolovska, Michael P. Cappillino, Bobby J. Cherayil, Daniel K. Podolsky, Koichi S. Kobayashi, Adam Lacy-Hulbert, and Lynda M. Stuart), The Journal of biological chemistry (2010)
 

Immunity, Humoral

Link

NF-kappaB/Rel Proteins and the Humoral Immune Responses of Drosophila melanogaster (with Sandhya Ganesan, Kamna Aggarwal, and Nicholas Paul Paquette), Current topics in microbiology and immunology (2010)