Matevosyan NR. The Risk of Cervical Cancer in Women who Partner with Women
AIM: To determine: (1) the risk of cervical cancer in women who partner with women (WPW) beyond the theory of papillomavirus infection; (2) the barriers for preventive screenings of WPW.
METHODS: Of the 90 retrieved papers 73 studies inclusive for suitable emperical evidence are allocated for meta-assessment. Applying multiple methods, one-time and life-time prevalence of cervical cancer, risk determinants (smoking, parity, psychosocial aspects, metabolic causes, health inequalities, client-provider communucations, barriers for preventive screenings), and outcomes (histological variances, grades, proximal and distant recurrance, survival, mortality) from 21,836 WPW and 14,350 control are modeled as measurable outcomes.
RESULTS & CONCLUSIONS: Higher rates of smoking (RR 3.15), overweight (OR 1.83), earlier onset of sexual activity (OR 1.97), number of sex partners (OR 2.4), childhood sexual abuse (RR 3.05), viral genital infections (RR 1.25), lack of social support (RR 3.4), anxiety and depression (RR 2.36), poor client-provider communciations (RR 3.43), poor perceptions of risk (RR 4.16), lack of preventive screenings (RR 4.28) determine the higher risk in WPW. After adjustment for social and economical variables, childhood sexual abuse remains in persistent associations with adult manifestations of clinical depression (.786), smoking (.865), and avoidance of gynecological screenings (.901). Further research is essential to elucidate metabolic factors (leptin, trace elements, Cu/Zn ratio), histological variance of the tumor, recurrence/survival ratio, and mortality rates in WPW.
. "Matevosyan NR. The Risk of Cervical Cancer in Women who Partner with Women" APHA (2012).
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