The rapidly changing global environment for community practice social workers (CPSWs) has challenged these practitioners to devise innovative intervention strategies. Some practitioners are utilising community organising, community planning, community development and policy practice intervention strategies simultaneously to create sustainable changes and are unwittingly, or purposefully, acting as social entrepreneurs. This article delineates similarities between community practice social work and social entrepreneurship – orientation and behaviours – and introduces the concept of community practice social entrepreneurship (CPSE). The authors propose interdisciplinary venues to teach graduate students in social work and in other disciplines skills for practicing as community practice social entrepreneurs.