Dr. Minoti Hiremath came to Boise State University as a research professor in January of 2011. She holds a Ph.D. in Cell Biology from New York University School of Medicine, and served as a Post-Doctoral Associate at Yale University from 2007-2010. Dr. Hiremath studies epithelial-mesenchymal interactions in embryonic mammary development, and the role of stromal Wnt signaling in breast cancer formation.
Articles
Parathyroid Hormone-Related Protein is Not Required for Normal Ductal or Alveolar Development in the Post-Natal Mammary Gland (with Kata Boras-Granic, Joshua VanHouten, and John Wysolmerski), PLoS ONE (2011)
PTHrP is necessary for the formation of the embryonic mammary gland and, in its absence,...
A Mouse Transgenic Approach to Induce β-Catenin Signaling in a Temporally Controlled Manner (with Atish Mukherjee, Selma M. Soyal, Jie Li, Yan Ying, Maria M. Szwarc, Bin He, Ramakrishna Kommagani, Myles C. Hodgson, Pamela Cowin, and John P. Lydon), Transgenic Research (2010)
Although constitutive murine transgenic models have provided important insights into β-catenin signaling in tissue morphogenesis...
Analysis of Gene Expression in PTHrP−/− Mammary Buds Supports a Role for BMP Signaling and MMP2 in the Initiation of Ductal Morphogenesis (with Julie Hens, Pamela Dann, Tien-Chi Pan, Lewis Chodosh, and John Wysolmerski), Developmental Dynamics (2009)
Parathyroid hormone–related protein (PTHrP) acts on the mammary mesenchyme and is required for proper embryonic...
MMTV-Wnt1 and -DN89b-Catenin Induce Canonical Signaling in Distinct Progenitors and Differentially Activate Hedgehog Signaling within Mammary Tumors (with Brigitte Teissedre, Alicia Pinderhughes, Angela Incassati, Sarah J. Hatsell, and Pamela Cowin), PLoS ONE (2009)
Canonical Wnt/b-catenin signaling regulates stem/progenitor cells and, when perturbed, induces many human cancers. A significant...
The Pattern Of β-Catenin-Responsiveness within the Mammary Gland is Regulated by Progesterone Receptor (with John Lydon and Pamela Cowin), Development (2007)
Experiments involving β-catenin loss- and gain-of-function in the mammary gland have decisively demonstrated the role...
Contributions to Books
Cadherins in Metastasis (with Pamela Cowin), New Developments in Metastasis Suppressor Research (2007)
Cadherins participate in calcium-dependent cell-cell adhesion. Although numerous models have been proposed for cadherin-cadherin interactions,...
Molecular, Cellular, and Developmental Biology of Breast Cancer (with S. J. Hatsell, P. Shamamian, and P. Cowin), Breast Cancer (2005)
Presentations
PTHrP-Induced Wnt Signaling Plays a Role in Specification of the Mammary Mesenchyme (with P. Dann and J. J. Wysolmerski), Poster Presentation/ENDO Society Meeting (2010)
PTHrP regulates mammary cell fate by specifying the mammary mesenchyme during embryonic mammary development. Loss...