Article
Global population-specific variation in miRNA associated with cancer risk and clinical biomarkers
BMC Medical Genomics
(2014)
Abstract
Background: MiRNA expression profiling is being actively investigated as a clinical biomarker and diagnostic tool to detect multiple cancer types and stages as well as other complex diseases. Initial investigations, however, have not comprehensively taken into account genetic variability affecting miRNA expression and/or function in populations of different ethnic backgrounds. Therefore, more complete surveys of miRNA genetic variability are needed to assess global patterns of miRNA variation within and between diverse human populations and their effect on clinically relevant miRNA genes.
Publication Date
August, 2014
DOI
10.1186/1755-8794-7-53
Citation Information
Renata A Rawlings-Goss, Michael C Campbell and Sarah A Tishkoff. "Global population-specific variation in miRNA associated with cancer risk and clinical biomarkers" BMC Medical Genomics Vol. 7 Iss. 53 (2014) Available at: http://works.bepress.com/michael-campbell/2/