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Article
Sequential reactions with Grubbs catalyst and AD-mix-alpha/beta using PDMS thimbles
Organic Letters
(2008)
Abstract
Incompatible Grubbs catalyst and an osmium dihydroxylation catalyst were site-isolated from each other using polydimethylsiloxane thimbles. The Grubbs catalyst was added to the interior of the thimbles, and AD-mix-alpha/beta was added to the exterior. Organic substrates readily fluxed through the walls of the thimbles and reacted with each catalyst. A series of cascade reactions were developed including those with intermediates possessing low boiling points or that were foul smelling.
Disciplines
Publication Date
September, 2008
Citation Information
Martin T. Mwangi, Michael D. Schulz and Ned B. Bowden. "Sequential reactions with Grubbs catalyst and AD-mix-alpha/beta using PDMS thimbles" Organic Letters Vol. 11 Iss. 1 (2008) Available at: http://works.bepress.com/martin_thuo/2/