Dr. Offield was born in Fort Worth, TX but spent most of his childhood in a west Texas oil town called Breckenridge. Dr. Offield is a 1988 graduate of Liberty's Biology program. He did his Master's research at Texas A&M were his research involved neural toxicology where he worked towards a cell culture method for assaying chemicals that are toxic to the nervous system. Dr. Offield obtained his PhD at Vanderbilt University in Nashville, TN where he also meet his wife, Donna. At Vanderbilt, Dr. Offield studied the role of a protein called PDX-1 which helps to control the production of insulin. His research showed that during the development of the embryo, PDX-1 is the master control gene for the pancreas.
Articles
The Development of Xenopus tropicalis Transgenic Lines and their Use in Studying Lens Developmental Timing in Living Embryos (with Nicholas Hirsch and Robert M. Grainger), Development (2000)
The generation of reporter lines for observing lens differentiation in vivo demonstrates a new strategy...
Hepatocyte Nuclear Factor 3beta is Involved in Pancreatic Beta-Cell-Specific Transcription of the PDX-1 Gene (with Kou-Liang Wu, Maureen Gannon, Mina Peshavaria, Eva Henderson, Michael Ray, Antonio Marks, Laura W. Gamer, Christopher V.E. Wright, and Roland Stein), Molecular and Cellular Biology (1997)
The mammalian homeobox gene pdx-1 is expressed in pluripotent precursor cells in the dorsal and...
PDX-1 is Required for Posterior Poregut Patterning and Differentiation of the Pancreas and Duodenum, Faculty Dissertations (1996)
The Xenopus homeobox gene, XlHbox8, has been proposed to be involved in endodermal differentiation, specifically...
PDX-1 is required for pancreatic out-growth and differentiation of the rostral duodenum (with Tom L. Jetton, Patricia A. Labosky, Michael Ray, Roland W. Stein, Mark A. Magnuson, Brigid L.M. Hogan, and Christopher V.E. Wright), Development (1996)
It has been proposed that the Xenopus homeobox gene, XlHbox8, is involved in endodermal differentiation...