The most important innovation in e-learning in recent years has been the development of Learning Design software. Learning Design is based on the process' of learning rather than on the content to be learnt. The Learning Activity Management System (LAMS) is a new public domain, e-learning platform that enables educators to plan and implement sequences of collaborative learning activities. These 'learning sequences' are analogous to the traditional lesson plans that have always been an integral part of quality teaching. LAMS users can modify, share and/or reuse learning sequences with similar or different content. LAMS was developed by a team led by Professor James Dalziel at the E-learning Centre of Excellence at Macquarie University in Australia. In 2004 the author was awarded a NSW Premier's Macquarie Bank Science Teachers Scholarship to travel to the UK to work with schools involved in a large-scale trial of LAMS. This paper outlines how LAMS operates, examines the results of recent LAMS trials at secondary schools and tertiary institutions in the UK and assesses the potential of LAMS to enhance science teaching and learning in secondary schools in NSW.