The Principles of Responsible Management Education (PRME) offer a platform for institutional commitment and leadership engagement toward business ethics and poverty alleviation. The author reviews the principles in light of a need for a renewed management education centered on social responsibility, sustainability and partnership values. The PRME present a possibility for universities to engage with United Nations Global Compact (UNGC), the Millennium Development Goals (MDGs) and other multi-stakeholder partnerships. The participating institutions share a commitment for a renewed management education where private organizations become positive agents for world benefit. The process of adopting and integrating the PRME into existing programs and curricula is instrumental for educating ethical, sustainable, and socially responsible leaders for the 21st century.