Articles
Supervillin modulation of focal adhesions involving TRIP6/ZRP-1 (with Norio Takizawa, Tara C. Smith, Thomas Nebl, Jessica L. Crowley, Stephen J. Palmieri, Lawrence M. Lifshitz, Anka G. Ehrhardt, Laura M. Hoffman, and Mary C. Beckerle), The Journal of cell biology (2006)
Cell-substrate contacts, called focal adhesions (FAs), are dynamic in rapidly moving cells. We show that...
Patellin1, a novel Sec14-like protein, localizes to the cell plate and binds phosphoinositides (with T. Kaye Peterman, Yamini M. Ohol, and Lisa J. McReynolds), Plant physiology (2004)
Membrane trafficking is central to construction of the cell plate during plant cytokinesis. Consequently, a...
Smooth muscle archvillin: a novel regulator of signaling and contractility in vascular smooth muscle (with Samudra S. Gangopadhyay, Norio Takizawa, Cynthia Gallant, Amy L. Barber, Hyun-Dong Je, Tara C. Smith, and Kathleen G. Morgan), Journal of cell science (2004)
The mechanisms by which protein kinase C (PKC) and extracellular-signal-regulated kinases (ERK1/2) govern smooth-muscle contractility...
Role of the cytoplasmic domain of the Newcastle disease virus fusion protein in association with lipid rafts (with V. Dolganiuc, Lori McGinnes, and Trudy G. Morrison), Journal of virology (2003)
To explore the association of the Newcastle disease virus (NDV) fusion (F) protein with cholesterol-rich...
F-actin and myosin II binding domains in supervillin (with Yu Chen, Norio Takizawa, Jessica L. Crowley, Sang W. Oh, Cheryl L. Gatto, Taketoshi Kambara, Osamu Sato, Xiang-Dong Li, and Mitsuo Ikebe), The Journal of biological chemistry (2003)
Detergent-resistant membranes contain signaling and integral membrane proteins that organize cholesterol-rich domains called lipid rafts....
Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton (with Sang W. Oh, Robert K. Pope, Kelly P. Smith, Jessica L. Crowley, Thomas Nebl, and Jeanne B. Lawrence), Journal of cell science (2003)
The membrane skeleton protein supervillin binds tightly to both F-actin and membranes and can potentiate...
Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes (with Thomas Nebl, Kersi N. Pestonjamasp, John D. Leszyk, Jessica L. Crowley, and Sang W. Oh), The Journal of biological chemistry (2002)
Plasma membranes are organized into functional domains both by liquid-ordered packing into "lipid rafts," structures...
Villin-type headpiece domains show a wide range of F-actin-binding affinities (with D. Vardar, A. H. Chishti, B. S. Frank, A. A. Noegel, Sang W. Oh, M. Schleicher, and C. J. McKnight), Cell motility and the cytoskeleton (2002)
The villin-type "headpiece" domain is a modular motif found at the extreme C-terminus of larger...
Mutant Rac1B expression in Dictyostelium: effects on morphology, growth, endocytosis, development, and the actin cytoskeleton (with S. J. Palmieri, Thomas Nebl, Robert K. Pope, D. J. Seastone, E. Lee, E. H. Hinchcliffe, Greenfield Sluder, D. Knecht, and J. Cardelli), Cell motility and the cytoskeleton (2000)
Rac1 is a small G-protein in the Ras superfamily that has been implicated in the...
Membrane cytoskeleton: PIP(2) pulls the strings (with Thomas Nebl and Sang W. Oh), Current biology : CB (2000)
A recent application of optical tweezers has shown that plasma membrane phosphatidylinositol 4,5-bisphosphate (PIP(2)) levels...
Regulation of F-actin binding to platelet moesin in vitro by both phosphorylation of threonine 558 and polyphosphatidylinositides (with F. Nakamura, L. Huang, Kersi N. Pestonjamasp, and H. Furthmayr), Molecular biology of the cell (1999)
Activation of human platelets with thrombin transiently increases phosphorylation at (558)threonine of moesin as determined...
Domain analysis of supervillin, an F-actin bundling plasma membrane protein with functional nuclear localization signals (with J. D. Wulfkuhle, I. E. Donina, N. H. Stark, Robert K. Pope, Kersi N. Pestonjamasp, and M. L. Niswonger), Journal of cell science (1999)
A growing number of actin-associated membrane proteins have been implicated in motile processes, adhesive interactions,...
Cloning, characterization, and chromosomal localization of human superillin (SVIL) (with Robert K. Pope, Kersi N. Pestonjamasp, K. P. Smith, J. D. Wulfkuhle, C. P. Strassel, and Jeanne B. Lawrence), Genomics (1998)
Supervillin is a 205-kDa F-actin binding protein originally isolated from bovine neutrophils. This protein is...
Merlin differs from moesin in binding to F-actin and in its intra- and intermolecular interactions (with L. Huang, E. Ichimaru, Kersi N. Pestonjamasp, X. Cui, H. Nakamura, G. Y. Lo, F. I. Lin, and H. Furthmayr), Biochemical and biophysical research communications (1998)
The neurofibromatosis type 2 (NF2) tumor suppressor gene encodes merlin, a protein with homology to...
Supervillin (p205): A novel membrane-associated, F-actin-binding protein in the villin/gelsolin superfamily (with Kersi N. Pestonjamasp, Robert K. Pope, and J. D. Wulfkuhle), The Journal of cell biology (1998)
Actin-binding membrane proteins are involved in both adhesive interactions and motile processes. We report here...
Ponticulin plays a role in the positional stabilization of pseudopods (with D. C. Shutt, D. Wessels, K. Wagenknecht, A. Chandrasekhar, A. L. Hitt, and D. R. Soll), The Journal of cell biology (1995)
Ponticulin is a 17-kD glycoprotein that represents a major high affinity link between the plasma...
Moesin, ezrin, and p205 are actin-binding proteins associated with neutrophil plasma membranes (with K. Pestonjamasp, M. R. Amieva, C. P. Strassel, W. M. Nauseef, and H. Furthmayr), Molecular biology of the cell (1995)
Actin-binding proteins in bovine neutrophil plasma membranes were identified using blot overlays with 125I-labeled F-actin....
Association of the Dictyostelium 30 kDa actin bundling protein with contact regions (with M. Fechheimer, H. M. Ingalls, and R. Furukawa), Journal of cell science (1994)
'Contact regions' are plasma membrane domains derived from areas of intercellular contact between aggregating Dictyostelium...
Ponticulin is an atypical membrane protein (with A. L. Hitt and T. H. Lu), The Journal of cell biology (1994)
We have cloned and sequenced ponticulin, a 17,000-dalton integral membrane glycoprotein that binds F-actin and...
Ponticulin is the major high affinity link between the plasma membrane and the cortical actin network in Dictyostelium (with A. L. Hitt and J. H. Hartwig), The Journal of cell biology (1994)
Interactions between the plasma membrane and underlying actin-based cortex have been implicated in membrane organization...
The integral membrane protein, ponticulin, acts as a monomer in nucleating actin assembly (with C. P. Chia, A. Shariff, and S. A. Savage), The Journal of cell biology (1993)
Ponticulin, an F-actin binding transmembrane glycoprotein in Dictyostelium plasma membranes, was isolated by detergent extraction...
Cytoskeleton--plasma membrane interactions (with A. L. Hitt), Science (New York, N.Y.) (1992)
Proteins at the boundary between the cytoskeleton and the plasma membrane control cell shape, delimit...
Diacylglycerol-stimulated formation of actin nucleation sites at plasma membranes (with A. Shariff), Science (New York, N.Y.) (1992)
Diacylglycerols, which are generated during phospholipase-catalyzed hydrolysis of phospholipids, stimulated actin polymerization in the presence...
Direct binding of F-actin to ponticulin, an integral plasma membrane glycoprotein (with C. P. Chia and A. L. Hitt), Cell motility and the cytoskeleton (1991)
We have developed an 125I-labeled F-actin blot overlay assay for the identification of F-actin-binding proteins...
Dictyostelium discoideum plasma membranes contain an actin-nucleating activity that requires ponticulin, an integral membrane glycoprotein (with A. Shariff), The Journal of cell biology (1990)
In previous equilibrium binding studies, Dictyostelium discoideum plasma membranes have been shown to bind actin...
How actin binds and assembles onto plasma membranes from Dictyostelium discoideum (with M. A. Schwartz), The Journal of cell biology (1988)
We have shown previously (Schwartz, M. A., and E. J. Luna. 1986. J. Cell Biol....
F-actin binds to the cytoplasmic surface of ponticulin, a 17-kD integral glycoprotein from Dictyostelium discoideum plasma membranes (with L. J. Wuestehube), The Journal of cell biology (1987)
F-actin affinity chromatography and immunological techniques are used to identify actin-binding proteins in purified Dictyostelium...
Junctional plasma membrane domains isolated from aggregating Dictyostelium discoideum amebae (with H. M. Ingalls and C. M. Goodloe-Holland), Proceedings of the National Academy of Sciences of the United States of America (1986)
Regions of plasma membrane involved in Dictyostelium discoideum intercellular adhesion resist solubilization with the nonionic...
Binding and assembly of actin filaments by plasma membranes from Dictyostelium discoideum (with M. A. Schwartz), The Journal of cell biology (1986)
The binding of native, 125I-Bolton-Hunter-labeled actin to purified Dictyostelium discoideum plasma membranes was measured using...
A membrane cytoskeleton from Dictyostelium discoideum. II. Integral proteins mediate the binding of plasma membranes to F-actin affinity beads (with C. M. Goodloe-Holland and H. M. Ingalls), The Journal of cell biology (1984)
In novel, low-speed sedimentation assays, highly purified, sonicated Dictyostelium discoideum plasma membrane fragments bind to...
A membrane cytoskeleton from Dictyostelium discoideum. III. Plasma membrane fragments bind predominantly to the sides of actin filaments (with C. M. Goodloe-Holland), The Journal of cell biology (1984)
The binding between sonicated Dictyostelium discoideum plasma membrane fragments and F-actin on Sephacryl S-1000 beads...
A stable, high capacity, F-actin affinity column (with Y. L. Wang, E. W. Voss Jr., D. Branton, and D. L. Taylor), The Journal of biological chemistry (1982)
A high capacity F-actin affinity matrix is constructed by binding fluorescyl-actin to rabbit anti-fluorescein IgG...
A membrane cytoskeleton from Dictyostelium discoideum. I. Identification and partial characterization of an actin-binding activity (with V. M. Fowler, J. Swanson, D. Branton, and D. L. Taylor), The Journal of cell biology (1981)
Dictyostelium discoideum plasma membranes isolated by each of three procedures bind F-actin. The interactions between...
Spectrin promotes the association of F-actin with the cytoplasmic surface of the human erythrocyte membrane (with V. M. Fowler, W. R. Hargreaves, D. L. Taylor, and D. Branton), The Journal of cell biology (1981)
We studied the binding of actin to the erythrocyte membrane by a novel application of...
Identification by peptide analysis of the spectrin-binding protein in human erythrocytes (with G. H. Kidd and D. Branton), The Journal of biological chemistry (1979)
One-dimensional and two-dimensional peptide-mapping techniques are used to identify the protein which gives rise to...