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Membrane cytoskeleton: PIP(2) pulls the strings

Thomas Nebl, University of Massachusetts Medical School
Sang W. Oh, University of Massachusetts Medical School
Elizabeth J. Luna, University of Massachusetts Medical School

Abstract

A recent application of optical tweezers has shown that plasma membrane phosphatidylinositol 4,5-bisphosphate (PIP(2)) levels control adhesion of the membrane bilayer to the underlying cytoskeleton, by regulated direct binding of PIP(2) to cytoskeletal proteins and/or indirect effects on cytoskeleton structure.

Suggested Citation

Thomas Nebl, Sang W. Oh, and Elizabeth J. Luna. "Membrane cytoskeleton: PIP(2) pulls the strings" Current biology : CB 10.9 (2000).
Available at: http://works.bepress.com/lunae/1

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