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Copper(II)-Catalyzed Exo and Enantioselective Cycloadditions of Azomethine Imines
Organic Letters (2008)
  • Mukund P. Sibi
  • Digamber Rane
  • Levi M. Stanley
  • Takahiro Soeta
Abstract

A strategy for exo and enantioselective 1,3-dipolar cycloaddition of azomethine imines to 2-acryloyl-3-pyrazolidinone is described. The corresponding cycloadducts are isolated with high diastereoselectivities (up to >96:4 exo/endo) and enantioselectivities (up to 98% ee).

Disciplines
Publication Date
June, 2008
Publisher Statement
Reprinted (adapted) with permission from Organic Letters 10 (2008): 2971, doi:10.1021/ol800904t. Copyright 2008 American Chemical Society.
Citation Information
Mukund P. Sibi, Digamber Rane, Levi M. Stanley and Takahiro Soeta. "Copper(II)-Catalyzed Exo and Enantioselective Cycloadditions of Azomethine Imines" Organic Letters Vol. 10 Iss. 14 (2008)
Available at: http://works.bepress.com/levi_stanley/7/