We examined parental education as predictors of vulnerability to biological and perceived chronic stressors into adulthood. Measures included hair cortisol (hCORT) and cardiovascular parameters as indicators of chronic stress and overall health. The community subjective social status ladder was included to examine relationships between maternal education and assessments of social standing in adult offspring. Participants (N = 107; ages 18-30; M =22.23, SD = 3.01; 50.4% female) were recruited from an urban public university and residents of surrounding low-income areas in Boston, MA. Maternal and paternal education were positively associated with change in sympathetic nervous system (SNS) recovery after a cognitive challenge task (rM =.22, p < .05, rP = .45, p < .001). Maternal education also predicted SNS resting and reactivity changes before and after the cognitive challenge (lower maternal education, higher resting SNS) (SymREST: F(2, 90) = 3.46, p < .05); and increased SNS reactivity during a cognitive stress task (SymTASK: F(2, 89) = 2.06, p < .05). Maternal education was negatively associated with hCORT (B =-.215, t(1, 104) =2.24, p < .05) (higher maternal education, lower hCORT). Additionally, maternal education predicted one’s present subjective status (higher maternal education, higher reported status on the SSS ladder) (F(2, 106) = 3.20, p < .05). These findings support work that finds parental education is a unique predictor that may influence vulnerabilities across biological and perceived domains in adulthood and call for analysis of underlying developmental mechanisms. [Supported by NIMHD 5P20MD002290 and Center for Clinical and Translational Sciences at University of Massachusetts Medical School]