Dr. Kristen Mitchell joined the faculty of Boise State University in January 2008. She earned her B.S. in Microbiology from Idaho State University in 1995, and her Ph.D. in Pharmacology/Toxicology from the Department of Pharmaceutical Sciences at Washington State University in Pullman, Washington in 2003. From 2003-2007, Dr. Mitchell conducted postdoctoral training in molecular toxicology at the University of Texas Medical Branch in Galveston, Texas. Dr. Mitchell's research interests focus on pharmacology and toxicology of the aryl hydrocarbon receptor (AhR). Specific research areas include immunotoxicity and inflammation associated with AhR ligands, and the role of the AhR in cell cycle regulation. Her research is currently supported by the NIH through grants from the Idaho Idea Network of Biomedical Research Excellence (INBRE), the Institute of Translational Health Sciences (ITHS), and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
Articles
Regulation of Hepatocyte Fate by Interferon-γ (with Christopher J. Horras and Cheri L. Lamb), Cytokine & Growth Factor Reviews (2011)
Interferon (IFN)-γ is a cytokine known for its immunomodulatory and anti-proliferative action. In the liver,...
The Activated Aryl Hydrocarbon Receptor Synergizes Mitogen-Induced Murine Liver Hyperplasia (with Shelly R. Wilson and Cornelis J. Elferink), Toxicology (2010)
Mechanisms of hepatocyte proliferation triggered by tissue loss are distinguishable from those that promote proliferation...
Timing is Everything: Consequences of Transient and Sustained AhR Activity (with Cornelis J. Elferink), Biochemical Pharmacology (2009)
The aryl hydrocarbon receptor (AhR) was implicated as a mediator of xenobiotic toxicity over three...
Sustained Aryl Hydrocarbon Receptor Activity Attenuates Liver Regeneration (with Courtney A. Lockhart, Gengming Huang, and Cornelis J. Elferink), Molecular Pharmacology (2006)
In hepatocyte-derived cell lines, either loss of aryl hydrocarbon receptor (AhR) function or treatment with...
The Aryl Hydrocarbon Receptor Predisposes Hepatocytes to Fas-Mediated Apoptosis (with Kyung-Tae Park, Gengming Huang, and Cornelis J. Elferink), Molecular Pharmacology (2005)
Liver homeostasis is achieved by the removal of diseased and damaged hepatocytes and their coordinated...
Press Releases
Boise State Sets University Records with 2011 NSF, NASA Research Funding (2011)
Boise State continues to advance its research agenda at a record-setting pace. The university attained...
Students Earn Top Honors at Regional Scientific Conference (2011)
Two Boise State students earned first place awards at the 92nd annual Pacific Division meeting...
Professor Explores Mysteries of Liver Regeneration through Grant (2010)
Kristen Mitchell, an assistant professor in the Department of Biological Sciences, has been awarded a...
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Consequences of TCDD Treatment on Intra-Hepatic Lymphocytes During Liver Regeneration (with Christopher J. Horras, Cheri L. Lamb, Allie L. King, and Jason R. Hanley), Journal of Immunotoxicology (2012)
Increasing evidence demonstrates a physiological role for the aryl hydrocarbon receptor (AhR) in regulating hepatocyte...