Pathophysiology of hepatitis C and HIV co-infection

Kenneth D. Phillips, University of South Carolina
R.B. Brewer

Abstract

Hepatitis C infection is the most common cause of chronic hepatitis that can lead to cirrhosis and hepatocellular cancer. Hepatitis C virus infects approximately 70 million people worldwide. Hepatitis C is usually transmitted by injection drug use and blood transfusion. Hepatitis C is prevalent in HIV-infected individuals. Coinfection complicates the treatment of these two distinct viral infections. Understanding the normal functions of the liver and the pathophysiological effects of coinfection enables health care professionals to provide the highest level of care for these individuals.