After earning a Ph.D. in Biochemistry and Molecular Biology from Oregon Health Sciences University, and serving as a Postdoctoral Fellow in Molecular Immunology at the Portland (OR) VA Medical Center, Dr. Ken Cornell joined the faculty of the Department of Chemistry and Biochemistry at Boise State University in 2004. Dr. Cornell's research interests include antibiotic development targeting bacterial and parasite methionine salvage, farnesol metabolism in eukaryotic cells, and development of forensic reagents. One of the primary investigations in his lab is the identification of new targets for antimicrobial drug development. Some of Dr. Cornell's current ongoing research support includes “A West Nile Virus Vaccine” Agency: DOD/CDMRP, Date: 09/09-08/10($940,000), “Global Consequences of Interruption of Microbial Autoinducer Signaling” Agency: NIH / Idaho INBRE, Date: 5/09-4/14 ($352,000), and “Acquisition of a Liquid Chromatography Tandem Mass Spectrometer” Agency: NSF MRI, Date: 08/09–07/12 ($597,877).
Articles
Dynamic Passivation with BSA Overcomes LTCC Mediated Inhibition of PCR (with Jason Besecker and Greg Hampikian), Sensors and Actuators B: Chemical (2013)
The increasing use of low temperature co-fired ceramic (LTCC) for the fabrication of biological microfluidic...
Methylthioadenosine/S-adenosylhomocysteine Nucleosidase, a Critical Enzyme for Bacterial Metabolism (with Nikhat Parveen), Molecular Microbiology (2011)
The importance of methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase in bacteria has started to be appreciated only in...
Structural Basis for α-Conotoxin Potency and Selectivity (with Matt Turner, Seth Eidemiller, Bryan Martin, Andrew Narver, Joshua Marshall, and Owen M. McDougal), Bioorganic & Medicinal Chemistry (2009)
Parkinson’s disease is a debilitating movement disorder characterized by altered levels of α6β2* nicotinic acetylcholine...
Assessment of methylthioadenosine/S-adenosylhomocysteine nucleosidases of Borrelia burgdorferi as Targets for Novel Antimicrobials Using a Novel High-Throughput Method (with Shekerah Primus, Jorge A. Martinez, and Nikhat Parveen), Journal of Antimicrobial Chemotherapy (2009)
Background: Lyme disease is the most prevalent tick-borne disease in the USA with the highest...
Molecular Determinants of Substrate Specificity in Plant 5′-Methylthioadenosine Nucleosidases (with Karen K.W. Siu, Jeffrey E. Lee, Janice R. Sufrin, Barbara A. Moffatt, Martin McMillan, Chelsea Isom, and P. Lynne Howell), Journal of Molecular Biology (2008)
5′-Methylthioadenosine (MTA)/S-adenosylhomocysteine (SAH) nucleosidase (MTAN) is essential for cellular metabolism and development in many bacterial...
Presentations
Optimizing Luciferase Reporter Vector Transfection in 5L Rat Hepatoma Cells (with Emily Calton, Reilly Clark, Ricky Aguayo, Jonathan Walsh, Cheri Lamb, Henry Charlier, and Kristen Mitchell), IDeA Network for Biomedical Research Excellence (INBRE) (2010)
Signal transducer and activator of transcription (STAT) 1 is a transcription factor activated by the...
Transfection of Luciferase Gene into 5L Cells to Monitor STAT Activation (with Andria Wellman, Christie Hammons, Robert Cox, Stephanie Saylor, Cheri L. Lamb, Henry Charlier, and Kristen A. Mitchell), IDeA Network for Biomedical Research Excellence (INBRE) (2010)
The cytokine interferon gamma (IFNγ) is a small, secreted protein that binds to its cognate...