KidsMatter and MindMatters are national initiatives that support student mental health promotion, prevention and early intervention in 4700+ primary and secondary schools across Australia. As part of a broad approach to reducing problem behaviour, such as bullying, KidsMatter and MindMatters offer resources and expertise. This paper presents evidence that these initiatives are making a difference to the lives of students with regard to reductions in bullying and harassment. Findings suggest that students feel safer in schools that have in place, opportunities to develop their skills to deal with bullying. Focus is given to strategies that support schools to reduce bullying by developing whole-school policy, prevention and management processes as part of their overall work in promoting mental health for the entire school community.