Article
Model-Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative
CPT: Pharmacometrics & Systems Pharmacology
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
1-1-2017
DOI
10.1002/psp4.12262
Abstract
There is growing concern about the limitations of rodent models with regard to recapitulation of human disease pathogenesis. Computational modeling of data from humans and animals sharing similar diseases provides an opportunity for parallel drug development in human and veterinary medicine. This “reverse translational” approach needs to be supported by continuing efforts to refine the in silico tools that allow extrapolation of results between species.
Creative Commons License
Creative Commons Attribution-NonCommercial 4.0 International
Copyright Owner
The Authors
Copyright Date
2017
Language
en
File Format
application/pdf
Citation Information
Benjamin Schneider, Violeta Balbas-Martinez, Albert E. Jergens, Inaki F. Troconiz, et al.. "Model-Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative" CPT: Pharmacometrics & Systems Pharmacology (2017) Available at: http://works.bepress.com/jonathan-mochel/5/
This article is published as Schneider, Benjamin, Violeta Balbas‐Martinez, Albert E. Jergens, Inaki F. Troconiz, Karin Allenspach, and Jonathan P. Mochel. "Model‐Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative." CPT: pharmacometrics & systems pharmacology (2017). doi: 10.1002/psp4.12262. Posted with permission.