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Article
Effect of dipterinyl calcium pentahydrate on hepatitis B virus replication in transgenic mice
J Transl Med (2010)
  • P Moheno
  • John D Morrey, Utah State University
  • D Fuchs
Abstract
Dipterinyl calcium pentahydrate (DCP) has previously been shown to inhibit MDA-MB-231 human breast cancer xenographs in nude mice in a manner correlated with increases in plasma IL-12 and IL-4 concentrations, and decreases in plasma IL-6 levels. DCP also inhibits indoleamine 2,3-dioxygenase (IDO), an immuno-inhibitory enzyme, in human PBMCs (Peripheral Blood Mononuclear Cells).
Keywords
  • Hepatitis B,
  • virus replication
Disciplines
Publication Date
January 1, 2010
Citation Information
Moheno, P., J. Morrey, and D. Fuchs. 2010. Effect of dipterinyl calcium pentahydrate on hepatitis B virus replication in transgenic mice. J Transl Med 8:32. PMID20356392 PMCPMC2853516