Article
Molecular Insights Into the Reversible formation of Tau Protein Fibrils
Chemical Communications
(2013)
Abstract
We computationally and experimentally showed that tau protein fibrils can be formed at high temperature. When cooled, the fibrils dissociate back to monomers. Heparin promotes tau fibril formation and prevents its reversion. Our results revealed the physicochemical mechanism of reversible formation of tau fibrils.
Disciplines
Publication Date
2013
Citation Information
Yin Luo, Paul Dinkel, Xiang Yu, Martin Margittai, et al.. "Molecular Insights Into the Reversible formation of Tau Protein Fibrils" Chemical Communications Vol. 49 Iss. 34 (2013) Available at: http://works.bepress.com/jie_zheng/2/