Despite the fact that osteopathic research is essential for the continued advancement of our profession, such research is lacking. One barrier is the attainment of funding resources to launch and continue quality research studies. In the present article, the authors outline resources for the early stages of research and provide guidance for grant proposal preparation, if it is determined that external funding is needed. Free and low-cost resources for obtaining preliminary data and sources of external funds are described. An overview of grant writing and information on where to obtain training is presented. Information on proposal writing basics, tips to increase the chances of success, the grant application process, and basic proposal and budget requirements is provided. Potential funding sources appropriate for beginning investigators are listed, as well. Suggestions are offered for revising and resubmitting unsuccessful proposals.