A Facile Synthesis of (tert-alkoxy)amines

Hasan Palandoken, University of California - Davis
Chris M. Bocian, University of California - Davis
Michelle R. McCombs, University of California - Davis
Michael H. Nantz, University of California - Davis

Article comments

Copyright © 2005 Elsevier. The definitive version is available at http://dx.doi.org/10.1016/j.tetlet.2005.07.149.

NOTE: At the time of publication, the author Hasan Palandoken was not yet affiliated with Cal Poly.

Abstract

Tertiary alcohols react with stoichiometric BF₃·Et₂O and N-hydroxyphthalimide to yield N-alkoxyphthalimides. Subsequent hydrazinolyses afford the title compounds.