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Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation
Biochemistry and Microbiology
  • Yeshi Yin, Marshall University
  • T. Ryan Withers, Marshall University
  • John R. W. Govan
  • Shannon L. Johnson
  • Hongwei D. Yu, Marshall University
Document Type
Article
Publication Date
9-1-2013
Abstract

A mutation in the mucA gene, which encodes a negative regulator of alginate production in Pseudomonas aeruginosa, is the main mechanism underlying the conversion to mucoidy in clinical isolates from patients with cystic fibrosis (CF). Here, we announce the draft genome sequence of the stable alginate-overproducing mucoid strain P. aeruginosa PAO581 with a mucA25 mutation, a derivative from the nonmucoid strains P. aeruginosa PAO381 and PAO1.

Comments

Genome Announcements is published by the American Society for Microbiology under the Creative Commons Attribution 3.0 Unported license.

Copyright © 2013 the authors.

Citation Information
Yin, Y., Withers, T. R., Govan, J. R., Johnson, S. L., & Yu, H. D. (2013). Draft genome sequence of a stable mucoid strain of Pseudomonas aeruginosa PAO581 with a mucA25 mutation. Genome Announcements, 1(5), e00834-13.