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Background: Recent studies suggest reduction of radical-propagating fatty acid hydroperoxides to inert hydroxides by interaction...
The molecular chaperone ¿B-crystallin is a small heat-shock protein that is upregulated in response to...
The well-characterized small heat-shock protein, alphaB-crystallin, acts as a molecular chaperone by interacting with unfolding...
"It has been widely accepted that mammalian spermatozoa are infertile when they leave the testes...
Intracellular 14-3-3 proteins bind to many proteins, via a specific phosphoserine motif, regulating diverse cellular...
Amyloid fibril formation is associated with diseases such as Alzheimer’s, Parkinson’s, and prion diseases. Inhibition...
Reduced and carboxymethylated-κ-casein (RCM-κ-CN) is a milk-derived amyloidogenic protein that readily undergoes nucleation-dependent aggregation and...
Small heat-shock proteins (sHsps) are molecular chaperones that play an important protective role against cellular...
Bovine milk kappa-casein forms a self-associating oligomeric micelle-like species, in equilibrium with dissociated forms. In...
alphaB-Crystallin is a small heat-shock protein (sHsp) that is colocalized with alpha-synuclein (alphaSyn) in Lewy...
Purpose: The molecular chaperone αB-crystallin is found in high concentrations in the lens and is...
Improper protein folding (misfolding) can lead to the formation of disordered (amorphous) or ordered (amyloid...
The polyphenol (-)-epigallocatechin-3-gallate (EGCG) has recently attracted much research interest in the field of protein-misfolding...
The amorphous aggregation of proteins is associated with many phenomena, ranging from the formation of...
The platypus epididymal proteome is being studied because epididymal proteins are essential for male fertility...
Selected dairy caseins have been shown to have capacity for chaperone-like regulation of folding pathways...
The present review examines whether monotremes may help to resolve three questions relating to sperm...
Thioflavin T (ThT) dye fluorescence is used regularly to quantify the formation and inhibition of...
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Molecular chaperones are a diverse group of proteins that stabilise partially folded target proteins to...
The calcified proteinaceous deposits, or corpora amylacea, of bovine mammary tissue often comprise a network...
Amyloid fibrils are aggregated and precipitated forms of protein in which the protein exists in...
Protein aggregation can proceed via disordered or ordered mechanisms, with the latter being associated with...
This mini-review focuses on the processes and consequences of protein folding and misfolding. The latter...
Alzheimer’s, Parkinson’s and Creutzfeldt-Jakob disease are associated with inappropriate protein deposition and ordered amyloid fibril...
AlphaB-Crystallin is a ubiquitous small heat-shock protein (sHsp) renowned for its chaperone ability to prevent...
Although it is generally understood that the testes recruited kidney ducts for reproductive function during...
Mass spectrometric analysis of a prion protein (PrP)-containing complex isolated from ram cauda epididymal fluid...
We have shown previously that a 'soluble' form of PrP (prion protein), not associated with...
The capacitation of mammalian spermatozoa involves the activation of a cAMP-mediated signal transduction pathway that...
Cellular prion protein (Prp(C)) is a glycoprotein usually associated with membranes via its glycosylphosphatidylinositol (GPI)...
When mammalian spermatozoa exit the testis, they show a highly specialized morphology; however, they are...
Capacitation has been correlated with the activation of a cAMP-PKA-dependent signaling pathway leading to protein...
We investigated the role of endogenous redox activity in regulating the signal transduction pathway leading...
The process of sperm capacitation is correlated with activation of a signal transduction pathway leading...
The ability of small heat-shock proteins (sHsps) such as alphaB-crystallin to inhibit the amorphous (disordered)...