Hydrolyzed Octadecyltrichlorosilane Functionalized with Amino Acid as Heterogeneous Enantioselective Catalaysts

Hadi Nur, University Technology Malaysia
Lim Kheng Wei, University Technology Malaysia
Salasiah Endud, University Technology Malaysia

Abstract

Heterogeneous asymmetric catalysts using amino acid as chiral promoter were synthesized by attachment of amino acids such as L-glutamic acid and L-phenylalanine onto the hydrophilic part of hydrolyzed octadecyltrichlorosilane (OTS). The catalysts exhibit 12-18% enantiomeric excess (ee) for the asymmetric hydration of epoxycyclohexene to yield (1R,2R)-trans-1,2-cyclohexanediol and (1S,2S)-trans-1,2-cyclohexanediol.