SelectedWorks of Gyongyi Szabo
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Gyongyi Szabo
University of Massachusetts Medical School
Professor of Medicine, Division of Gastroenterology, Department of Medicine
Associate Dean for Clinical and Translational Sciences
Director, MD/PhD Program
Contact Information
Curriculum Vitae [PDF]
Expertise
Gastroenterology
Honors & Awards
Elected to the Hungarian National Academy of Sciences (2013)
External Advisory Board Member, NIAAA, NIH (2009)
“Women in Science and Health Achievement Award," University of Massachusetts Medical School (2009)
Fellow in the 2009-2010 Class of the Hedwig van Ameringen Executive Leadership in Academic Medicine (ELAM) Program for Women (2009)
Kelsey Family Named Professor, Division of Gastroenterology and Hepatology at the Mayo Clinic (2009)
National Advisory Council on Alcohol Abuse and Alcoholism (2009-2013)
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Division of Gastroenterology
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Type III Interferons, IL-28 and IL-29, Are Increased in Chronic HCV Infection and Induce Myeloid Dendritic Cell-Mediated FoxP3+ Regulatory T Cells
(with Angela Dolganiuc, Karen Kodys, Christopher Marshall, Banishree Saha, Shuye Zhang, and Shashi Bala),
PloS one
(2012)
PDF
IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice
(with Jan Petrasek, Shashi Bala, Timea Csak, Dora Lippai, Karen Kodys, Victoria Menashy, Matthew Barrieau, So-Yun Min, and Evelyn A. Kurt-Jones),
The Journal of clinical investigation
(2012)
Link
Induction of Bcl-3 by acute binge alcohol results in Toll-like receptor 4/LPS tolerance
(with Shashi Bala, Alexander Tang, Donna Catalano, Jan Petrasek, Odette Taha, and Karen Kodys),
Journal of leukocyte biology
(2012)
Link
Inflammasomes in liver diseases
(with Timea Csak),
Journal of hepatology
(2012)
Link
Ethanol facilitates HCV replication via upregulation of GW182 and HSP90 in human hepatoma cells
(with Terence N. Bukong, Wei Hou, and Karen Kodys),
Hepatology (Baltimore, Md.)
(2012)
PDF
Human Monoclonal Antibody HCV1 Effectively Prevents and Treats HCV Infection in Chimpanzees
(with Trevor J. Morin, Teresa J. Broering, Brett A. Leav, Barbara M. Blair, Kirk J. Rowley, Elisabeth N. Boucher, Yang Wang, Peter S. Cheslock, Michael Knauber, David B. Olsen, Steve W. Ludmerer, Robert W. Finberg, Robert H. Purcell, Robert E. Lanford, Donna M. Ambrosino, Deborah C. Molrine, and Gregory J. Babcock),
PLoS pathogens
(2012)
Link
MicroRNA silencing and the development of novel therapies for liver disease
(with Peter Sarnow and Shashi Bala),
Journal of hepatology
(2012)
Link
The Presence of p47phox in Liver Parenchymal Cells is a Key Mediator in the Pathogenesis of Alcoholic Liver Steatosis
(with Ivan Levin and Jan Petrasek),
Alcoholism, clinical and experimental research
(2012)
PDF
Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection
(with Shashi Bala, Yaphet Tilahun, Odette Taha, Hawau Alao, Karen Kodys, and Donna Catalano),
Journal of translational medicine
(2012)
PDF
Plasma microRNA profiles distinguish lethal injury in acetaminophen toxicity: a research study
(with Jeanine Ward, Shashi Bala, and Jan Petrasek),
World journal of gastroenterology : WJG
(2012)
Link
Reduction in Hepatic Inflammation Is Associated With Less Fibrosis Progression and Fewer Clinical Outcomes in Advanced Hepatitis C
(with Chihiro Morishima, Mitchell L. Shiffman, Jules L. Dienstag, Karen L. Lindsay, Gregory T. Everson, Anna S. F. Lok, Adrian M. Di Bisceglie, Marc G. Ghany, Deepa Naishadham, Timothy R. Morgan, Elizabeth C. Wright, and HALT-C Trial Group),
The American journal of gastroenterology
(2012)
Link
Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases
(with Shashi Bala, Jan Petrasek, Shiv Mundkur, Donna Catalano, Ivan Levin, Jeanine Ward, Hawau Alao, and Karen Kodys),
Hepatology (Baltimore, Md.)
(2012)
Link
Molecular hepatic carcinogenesis: impact of inflammation
(with Dora Lippai),
Digestive diseases (Basel, Switzerland)
(2012)
Link
CD81/CD9 tetraspanins aid plasmacytoid dendritic cells in recognition of HCV-infected cells and induction of IFNalpha
(with Shuye Zhang, Karen Kodys, and Gregory J. Babcock),
Hepatology (Baltimore, Md.)
(2012)
Link
Novel developmental biology-based protocol of embryonic stem cell differentiation to morphologically sound and functional yet immature hepatocytes
(with Terence N. Bukong, Tracie Lo, and Angela Dolganiuc),
Liver international : official journal of the International Association for the Study of the Liver
(2012)
PDF
MicroRNA Signature in Alcoholic Liver Disease
(with Shashi Bala),
International journal of hepatology
(2012)
Link
Hypoxia and hypoxia inducible factors: diverse roles in liver diseases
(with Bharath D. Nath),
Hepatology (Baltimore, Md.)
(2012)
Link
Advanced molecular biologic techniques in toxicologic disease
(with Jeanine Ward, David D. McManus, and Edward W. Boyer),
Journal of medical toxicology : official journal of the American College of Medical Toxicology
(2011)
Link
An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice
(with Pranoti Mandrekar, Aditya Ambade, Arlene Lim, and Donna Catalano),
Hepatology (Baltimore, Md.)
(2011)
PDF
Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver
(with Michal Ganz, Timea Csak, and Bharath D. Nath),
World journal of gastroenterology : WJG
(2011)
PDF
Inhibition of TLR8- and TLR4-induced Type I IFN Induction by Alcohol is Different from its effects on inflammatory cytokine production in monocytes
(with Maoyin Pang, Shashi Bala, Karen Kodys, and Donna Catalano),
BMC immunology
(2011)
Link
A prospective study of the rate of progression in compensated, histologically advanced chronic hepatitis C
(with Jules L. Dienstag, Marc G. Ghany, Timothy R. Morgan, Adrian M. Di Bisceglie, Herbert L. Bonkovsky, Hae-Young Kim, Leonard B. Seeff, Elizabeth C. Wright, Richard K. Sterling, Gregory T. Everson, Karen L. Lindsay, William M. Lee, Anna S. F. Lok, Chihiro Morishima, Anne M. Stoddard, and James E. Everhart),
Hepatology (Baltimore, Md.)
(2011)
Link
Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
(with Timea Csak, Michal Ganz, Justin Pespisa, Karen Kodys, and Angela Dolganiuc),
Hepatology (Baltimore, Md.)
(2011)
Link
Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice
(with Timea Csak, Angela Dolganiuc, Karen Kodys, Bharath D. Nath, Jan Petrasek, Shashi Bala, and Dora Lippai),
Hepatology (Baltimore, Md.)
(2011)
PDF
Mechanisms of alcohol-mediated hepatotoxicity in human-immunodeficiency-virus-infected patients
(with Samir Zakhari),
World journal of gastroenterology : WJG
(2011)
Link
Hepatocyte-specific hypoxia-inducible factor-1alpha is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice
(with Bharath D. Nath, Ivan Levin, Timea Csak, Jan Petrasek, Christian Mueller, Karen Kodys, Donna Catalano, and Pranoti Mandrekar),
Hepatology (Baltimore, Md.)
(2011)
Link
Dendritic cells in hepatitis C infection: can they (help) win the battle
(with Angela Dolganiuc),
Journal of gastroenterology
(2011)
Link
Type I Interferons Protect From Toll-Like Receptor 9-Associated Liver Injury and Regulate IL-1 Receptor Antagonist in Mice
(with Jan Petrasek, Angela Dolganiuc, Timea Csak, and Evelyn A. Kurt-Jones),
Gastroenterology
(2011)
Link
Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells
(with Jan Petrasek, Angela Dolganiuc, Timea Csak, Bharath Dwaraka Nath, Istvan Hritz, Karen Kodys, Donna Catalano, Evelyn A. Kurt-Jones, and Pranoti Mandrekar),
Hepatology (Baltimore, Md.)
(2011)
Link
Innate immunity and alcoholic liver disease
(with Bin Gao, Ekihiro Seki, Jessica Cohen, Laura Nagy, and Samir Zakhari),
American journal of physiology. Gastrointestinal and liver physiology
(2011)
Link
Deficiency in myeloid differentiation factor-2 and Toll-like receptor 4 expression attenuates non-alcoholic steatohepatitis and fibrosis in mice
(with Timea Csak, Arumugam Velayudham, Istvan Hritz, Jan Petrasek, Ivan Levin, Dora Lippai, Donna Catalano, Pranoti Mandrekar, Angela Dolganiuc, and Evelyn A. Kurt-Jones),
American journal of physiology. Gastrointestinal and liver physiology
(2011)
Link
Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease
(with Shashi Bala, Miguel Marcos, Karen Kodys, Timea Csak, Donna Catalano, and Pranoti Mandrekar),
The Journal of biological chemistry
(2011)
PDF
Toll-like receptor signaling in liver diseases
(with Timothy R. Billiar, Keigo Machida, Ian Nicholas Crispe, and Ekihiro Seki),
Gastroenterology research and practice
(2010)
Link
Alcohol exposure as a risk factor for adverse outcomes in elective surgery
(with Bharath Dwaraka Nath, YouFu Li, James E. Carroll Jr., Jennifer F. Tseng, and Shimul A. Shah),
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
(2010)
Link
Alcohol and hepatitis C virus--interactions in immune dysfunctions and liver damage
(with Jack R. Wands, Ahment Eken, Natalia A. Osna, Steven A. Weinman, Keigo Machida, and Joe H. Wang),
Alcoholism, clinical and experimental research
(2010)
PDF
Toll-like receptors in the pathogenesis of alcoholic liver disease
(with Jan Petrasek and Pranoti Mandrekar),
Gastroenterology research and practice
(2010)
Link
The 40th anniversary of the National Institute on Alcoholism and Alcohol Abuse: the impact on liver disease
,
Hepatology (Baltimore, Md.)
(2010)
PDF
Alcoholic liver disease and the gut-liver axis
(with Shashi Bala),
World journal of gastroenterology : WJG
(2010)
Link
Factors that determine the development and progression of gastroesophageal varices in patients with chronic hepatitis C
(with Robert J. Fontana, Arun J. Sanyal, Marc G. Ghany, William M. Lee, Andrea E. Reid, Deepa Naishadham, Gregory T. Everson, Jeffrey A. Kahn, Adrian M. Di Bisceglie, Timothy R. Morgan, and James E. Everhart),
Gastroenterology
(2010)
Link
Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cells
(with Serena S. Chang and Karen Kodys),
Hepatology (Baltimore, Md.)
(2010)
PDF
Emerging role of microRNAs in liver diseases
(with Shashi Bala and Miguel Marcos),
World journal of gastroenterology : WJG
(2009)
Link
MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice
(with Angela Dolganiuc, Jan Petrasek, Karen Kodys, Donna Catalano, Pranoti Mandrekar, and Arumugam Velayudham),
Alcoholism, clinical and experimental research
(2009)
Link
The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes
(with Pranoti Mandrekar, Shashi Bala, Donna Catalano, and Karen Kodys),
Journal of immunology (Baltimore, Md. : 1950)
(2009)
Link
Signalling pathways in alcohol-induced liver inflammation
(with Pranoti Mandrekar),
Journal of hepatology
(2009)
Link
Alcohol-induced modulation of signaling pathways in liver parenchymal and nonparenchymal cells: implications for immunity
(with Bharath D. Nath),
Seminars in liver disease
(2009)
PDF
In vitro and in vivo models of acute alcohol exposure
(with Angela Dolganiuc),
World journal of gastroenterology : WJG
(2009)
Link
The "health" and future of the physician-scientist in hepatology
,
Hepatology (Baltimore, Md.)
(2009)
Link
VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice
(with Arumugam Velayudham, Angela Dolganiuc, Michael Ellis, Jan Petrasek, Karen Kodys, and Pranoti Mandrekar),
Hepatology (Baltimore, Md.)
(2008)
Link
Antigen-presenting cells under the influence of alcohol
(with Audrey H. Lau and Angus W. Thomson),
Trends in immunology
(2008)
Link
A recent perspective on alcohol, immunity, and host defense
(with Pranoti Mandrekar),
Alcoholism, clinical and experimental research
(2008)
Link
Myeloid dendritic cells of patients with chronic HCV infection induce proliferation of regulatory T lymphocytes
(with Angela Dolganiuc, Edward Paek, Karen Kodys, and Joanne Thomas),
Gastroenterology
(2008)
Link
Bone marrow-derived immune cells mediate sensitization to liver injury in a myeloid differentiation factor 88-dependent fashion
(with Istvan Hritz, Arumugam Velayudham, Angela Dolganiuc, Karen Kodys, Pranoti Mandrekar, and Evelyn A. Kurt-Jones),
Hepatology (Baltimore, Md.)
(2008)
Link
The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88
(with Istvan Hritz, Pranoti Mandrekar, Arumugam Velayudham, Donna Catalano, Angela Dolganiuc, Karen Kodys, and Evelyn A. Kurt-Jones),
Hepatology (Baltimore, Md.)
(2008)
Link
Hepatitis C and innate immunity: recent advances
(with Angela Dolganiuc),
Clinics in liver disease
(2008)
Link
Acute alcohol intake induces SOCS1 and SOCS3 and inhibits cytokine-induced STAT1 and STAT3 signaling in human monocytes
(with Oxana Norkina, Angela Dolganiuc, Donna Catalano, Karen Kodys, Pranoti Mandrekar, Amber Syed, and Marian Efros),
Alcoholism, clinical and experimental research
(2008)
Link
T cells with regulatory activity in hepatitis C virus infection: what we know and what we don't
(with Angela Dolganiuc),
Journal of leukocyte biology
(2008)
Link
Human monocytes, macrophages, and dendritic cells: alcohol treatment methods
(with Pranoti Mandrekar),
Methods in molecular biology (Clifton, N.J.)
(2008)
Link
The role of plasmacytoid dendritic cell-derived IFN alpha in antiviral immunity
(with Angela Dolganiuc),
Critical reviews in immunology
(2008)
Link
Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial
(with Leonard B. Seeff, Teresa M. Curto, Gregory T. Everson, Herbert L. Bonkovsky, Jules L. Dienstag, Mitchell L. Shiffman, Karen L. Lindsay, Anna S. F. Lok, Adrian M. Di Bisceglie, William M. Lee, and Marc G. Ghany),
Hepatology (Baltimore, Md.)
(2007)
Link
Hepatitis C core protein - the "core" of immune deception
(with Angela Dolganiuc),
Journal of hepatology
(2007)
Link
Innate immune response and hepatic inflammation
(with Pranoti Mandrekar and Angela Dolganiuc),
Seminars in liver disease
(2007)
Link
Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance in chronic HCV infection
(with Angela Dolganiuc, Oxana Norkina, Karen Kodys, Donna Catalano, Gennadiy Bakis, Christopher Marshall, and Pranoti Mandrekar),
Gastroenterology
(2007)
Link
Altered innate immunity in chronic hepatitis C infection: cause or effect
(with Serena S. Chang and Angela Dolganiuc),
Hepatology (Baltimore, Md.)
(2007)
Link
Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins
(with Serena S. Chang and Angela Dolganiuc),
Journal of leukocyte biology
(2007)
Link
Effect of ethanol on inflammatory responses. Implications for pancreatitis
(with Pranoti Mandrekar, Shilpa Oak, and Julia Mayerle),
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
(2007)
Link
Acute alcohol activates STAT3, AP-1, and Sp-1 transcription factors via the family of Src kinases to promote IL-10 production in human monocytes
(with Oxana Norkina, Angela Dolganiuc, Taryn Shapiro, Karen Kodys, and Pranoti Mandrekar),
Journal of leukocyte biology
(2007)
Link
Acute alcohol exposure exerts anti-inflammatory effects by inhibiting IkappaB kinase activity and p65 phosphorylation in human monocytes
(with Pranoti Mandrekar, Valentina Jeliazkova, and Donna Catalano),
Journal of immunology (Baltimore, Md. : 1950)
(2007)
Link
Moderate Drinking, Inflammation, and Liver Disease
,
Annals of Epidemiology
(2007)
Link
TLR4, ethanol, and lipid rafts: a new mechanism of ethanol action with implications for other receptor-mediated effects
(with Angela Dolganiuc, Qun Dai, and Stephen B. Pruett),
Journal of immunology (Baltimore, Md. : 1950)
(2007)
Link
HCV immunopathogenesis: virus-induced strategies against host immunity
(with Angela Dolganiuc),
Clinics in liver disease
(2006)
Link
Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection
(with Angela Dolganiuc, Serena S. Chang, Karen Kodys, Pranoti Mandrekar, Gennadiy Bakis, and Maureen Cormier),
Journal of immunology (Baltimore, Md. : 1950)
(2006)
Link
Critical role of toll-like receptors and the common TLR adaptor, MyD88, in induction of granulomas and liver injury
(with Arumugam Velayudham, Istvan Hritz, Angela Dolganiuc, Pranoti Mandrekar, and Evelyn A. Kurt-Jones),
Journal of hepatology
(2006)
Link
Heme oxygenase-1 mediates the anti-inflammatory effects of acute alcohol on IL-10 induction involving p38 MAPK activation in monocytes
(with Yvonne Drechsler, Angela Dolganiuc, Oxana Norkina, Laszlo Romics, Weibo Li, Karen Kodys, Fritz H. Bach, and Pranoti Mandrekar),
Journal of immunology (Baltimore, Md. : 1950)
(2006)
Link
Pattern recognition receptors: a contemporary view on liver diseases
(with Angela Dolganiuc and Pranoti Mandrekar),
Hepatology (Baltimore, Md.)
(2006)
Link
The emerging role of toll-like receptor pathways in surgical diseases
(with Laszlo Romics, John Calvin Coffey, Jiang Huai Wang, and Henry Paul Redmond),
Archives of surgery (Chicago, Ill. : 1960)
(2006)
Link
TLR2- and TLR4-mediated signals determine attenuation or augmentation of inflammation by acute alcohol in monocytes
(with Shilpa A. Oak, Pranoti Mandrekar, Donna Catalano, and Karen Kodys),
Journal of immunology (Baltimore, Md. : 1950)
(2006)
Link
Intervention at the level of the neuroendocrine-immune axis and postoperative pneumonia rate in long-term alcoholics
(with Claudia Spies, Verena Eggers, Alexandra Lau, Vera von Dossow, Helge Schoenfeld, Hilke Althoff, Katrin Hegenscheid, Birgit Bohm, Torsten Schroeder, Sebastian Pfeiffer, Sabine Ziemer, Christian Paschen, Martin Klein, Christian Marks, Peter Miller, Michael Sander, Klaus-D. Wernecke, Evelin Achterberg, Udo Kaisers, and Hans-Dieter Volk),
American journal of respiratory and critical care medicine
(2006)
Link
Cytokines and alcohol
(with Fulton T. Crews, Rabih Bechara, Lou Ann Brown, David M. Guidot, Pranoti Mandrekar, Shilpa Oak, Liya Qin, Michael Wheeler, and Jian Zou),
Alcoholism, clinical and experimental research
(2006)
Link
Hepatitis C infection and alcohol use: A dangerous mix for the liver and antiviral immunity
(with Costica Aloman, Stephen J. Polyak, Steven A. Weinman, Jack Wands, and Samir Zakhari),
Alcoholism, clinical and experimental research
(2006)
PDF
Distinct Toll-like receptor expression in monocytes and T cells in chronic HCV infection
(with Angela Dolganiuc, Catherine Garcia, and Karen Kodys),
World journal of gastroenterology : WJG
(2006)
Link
Hepatitis C virus NS5A protein--a master regulator
,
Gastroenterology
(2006)
Link
Acute ethanol treatment modulates Toll-like receptor-4 association with lipid rafts
(with Angela Dolganiuc, Genadyi Bakis, Karen Kodys, and Pranoti Mandrekar),
Alcoholism, clinical and experimental research
(2006)
Link
Moderate alcohol intake in humans attenuates monocyte inflammatory responses: inhibition of nuclear regulatory factor kappa B and induction of interleukin 10
(with Pranoti Mandrekar, Donna Catalano, and Bernadette M. White),
Alcoholism, clinical and experimental research
(2006)
Link
Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4
(with Arumugam Velayudham, Laszlo Romics, and Pranoti Mandrekar),
Alcoholism, clinical and experimental research
(2005)
Link
RSA 2004: combined basic research satellite symposium - session four: hepatitis virus and alcohol interactions in immunity and liver disease
(with Steven A. Weinman, Bin Gao, Stephen J. Polyak, Pranoti Mandrekar, and Geoffrey M. Thiele),
Alcoholism, clinical and experimental research
(2005)
Link
RSA 2004: combined basic research satellite symposium - session three: alcohol and mitochondrial metabolism: at the crossroads of life and death
(with Jan B. Hoek, Victor Darley-Usmar, Gyorgy Hajnoczky, Thomas Knudsen, Daria Mochly-Rosen, and Samir Zakhari),
Alcoholism, clinical and experimental research
(2005)
Link
RSA 2004: combined basic research satellite symposium - session two: toll-like receptors and organ damage
(with Pranoti Mandrekar, Stephen B. Pruett, Gavin Arteel, and Geoffrey M. Thiele),
Alcoholism, clinical and experimental research
(2005)
Link
Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes
(with Laszlo Romics, Angela Dolganiuc, Arumugam Velayudham, Karen Kodys, Pranoti Mandrekar, Douglas Golenbock, and Evelyn A. Kurt-Jones),
Journal of leukocyte biology
(2005)
Link
Subversion of plasmacytoid and myeloid dendritic cell functions in chronic HCV infection
(with Angela Dolganiuc),
Immunobiology
(2005)
Link
Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression
(with Laszlo Romics, Pranoti Mandrekar, Karen Kodys, Arumugam Velayudham, Yvonne Drechsler, and Angela Dolganiuc),
Alcoholism, clinical and experimental research
(2005)
Link
Inhibition of antigen-presenting cell functions by alcohol: implications for hepatitis C virus infection
(with Angela Dolganiuc, Pranoti Mandrekar, and Bernadette M. White),
Alcohol (Fayetteville, N.Y.)
(2004)
Link
Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation
(with Angela Dolganiuc, Shilpa Oak, Karen Kodys, Douglas T. Golenbock, Robert W. Finberg, and Evelyn A. Kurt-Jones),
Gastroenterology
(2004)
Link
Diverse regulation of NF-kappaB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver
(with Laszlo Romics, Karen Kodys, Angela Dolganiuc, Lucia Graham, Arumugam Velayudham, and Pranoti Mandrekar),
Hepatology (Baltimore, Md.)
(2004)
Link
Selective priming to Toll-like receptor 4 (TLR4), not TLR2, ligands by P. acnes involves up-regulation of MD-2 in mice
(with Laszlo Romics, Angela Dolganiuc, Karen Kodys, Yvonne Drechsler, Shilpa Oak, Arumugam Velayudham, and Pranoti Mandrekar),
Hepatology (Baltimore, Md.)
(2004)
Link
Inhibition of myeloid dendritic cell accessory cell function and induction of T cell anergy by alcohol correlates with decreased IL-12 production
(with Pranoti Mandrekar, Donna Catalano, Angela Dolganiuc, and Karen Kodys),
Journal of immunology (Baltimore, Md. : 1950)
(2004)
Link
Acute alcohol consumption inhibits accessory cell function of monocytes and dendritic cells
(with Donna Catalano, Bernadette White, and Pranoti Mandrekar),
Alcoholism, clinical and experimental research
(2004)
Link
Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 induction
(with Angela Dolganiuc, Karen Kodys, Andrea Kopasz, Christopher Marshall, and Pranoti Mandrekar),
Alcoholism, clinical and experimental research
(2003)
Link
Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation
(with Angela Dolganiuc, Karen Kodys, Andrea Kopasz, Christopher Marshall, Twan Do, Laszlo Romics, Pranoti Mandrekar, and Maria L. Zapp),
Journal of immunology (Baltimore, Md. : 1950)
(2003)
Link
Pathogenic interactions between alcohol and hepatitis C
,
Current gastroenterology reports
(2003)
Link
Liver in sepsis and systemic inflammatory response syndrome
(with Laszlo Romics and Gyorgy Frendl),
Clinics in liver disease
(2003)
Link
Inhibition of NF-kappa B binding correlates with increased nuclear glucocorticoid receptor levels in acute alcohol-treated human monocytes
(with Pranoti Mandrekar and Gary Bellerose),
Alcoholism, clinical and experimental research
(2002)
Link
Modulation of immunity and viral-host interactions by alcohol
(with Geoffrey M. Thiele, Elizabeth J. Kovacs, Abraham P. Bautista, Laura Sosa, and Thomas R. Jerrells),
Alcoholism, clinical and experimental research
(2002)
Link
Acute alcohol inhibits the induction of nuclear regulatory factor kappa B activation through CD14/toll-like receptor 4, interleukin-1, and tumor necrosis factor receptors: a common mechanism independent of inhibitory kappa B alpha degradation
(with Pranoti Mandrekar, Angela Dolganiuc, Gary Bellerose, Karen Kodys, Laszlo Romics, and Rabia Nizamani),
Alcoholism, clinical and experimental research
(2002)
Link
FcgammaR cross-linking mediates NF-kappaB activation, reduced antigen presentation capacity, and decreased IL-12 production in monocytes without modulation of myeloid dendritic cell development
(with Yvonne Drechsler, Sangeeta S. Chavan, Donna Catalano, and Pranoti Mandrekar),
Journal of leukocyte biology
(2002)
Link
Severe cholestatic hepatitis caused by thiazolidinediones: risks associated with substituting rosiglitazone for troglitazone
(with Herbert L. Bonkovsky, Riad Azar, Steven Bird, and Barbara Banner),
Digestive diseases and sciences
(2002)
Link
Ethanol-mediated regulation of transcription factors in immunocompetent cells
(with Pranoti Mandrekar),
Frontiers in bioscience : a journal and virtual library
(2002)
Link
Reduced alloreactive T-cell activation after alcohol intake is due to impaired monocyte accessory cell function and correlates with elevated IL-10, IL-13, and decreased IFNgamma levels
(with Pranoti Mandrekar, Angela Dolganiuc, Donna Catalano, and Karen Kodys),
Alcoholism, clinical and experimental research
(2002)
Link
Tacrolimus and cyclosporine A inhibit allostimulatory capacity and cytokine production of human myeloid dendritic cells
(with C. Gavala and Pranoti Mandrekar),
Journal of investigative medicine : the official publication of the American Federation for Clinical Research
(2001)
Link
Interferon alpha and alcohol augment nuclear regulatory factor-kappaB activation in HepG2 cells, and interferon alpha increases pro-inflammatory cytokine production
(with Donna Catalano, Gary Bellerose, and Pranoti Mandrekar),
Alcoholism, clinical and experimental research
(2001)
Link
Management of recurrent hepatitis C after liver transplantation: a concise review
(with Eliezer Katz and Herbert L. Bonkovsky),
The American journal of gastroenterology
(2000)
Link
Acceptance of an ABO-incompatible mismatched (AB(+) to O(+)) liver allograft with the use of daclizumab and mycophenolate mofetil
(with W. Christopher Fang, John R. Saltzman, Sarah Rososhansky, Stephen O. Heard, Barbara F. Banner, Ravi Chari, and Eliezer Katz),
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
(2000)
Link
New insights into the the molecular mechanisms of alcoholic hepatitis: a potential role for NF-kappaB activation
,
The Journal of laboratory and clinical medicine
(2000)
Link
Consequences of alcohol consumption on host defence
,
Alcohol and alcoholism (Oxford, Oxfordshire)
(2000)
PDF
Inhibition of lipopolysaccharide-mediated NFkappaB activation by ethanol in human monocytes
(with Pranoti Mandrekar and Donna Catalano),
International immunology
(1999)
Link
Acute alcohol consumption attenuates interleukin-8 (IL-8) and monocyte chemoattractant peptide-1 (MCP-1) induction in response to ex vivo stimulation
(with Sangeeta Chavan, Pranoti Mandrekar, and Donna Catalano),
Journal of clinical immunology
(1999)
Link
Regulation of monocyte IL-12 production: augmentation by lymphocyte contact and acute ethanol treatment, inhibition by elevated intracellular cAMP
(with Linda Girouard, Pranoti Mandrekar, and Donna Catalano),
International journal of immunopharmacology
(1998)
Link
Monocytes, alcohol use, and altered immunity
,
Alcoholism, clinical and experimental research
(1998)
Link
Regulation of monocyte interleukin-12 production by acute alcohol: a role for inhibition by interleukin-10
(with Linda Girouard, Pranoti Mandrekar, and Donna Catalano),
Alcoholism, clinical and experimental research
(1998)
Link
Alcohol's contribution to compromised immunity
,
Alcohol health and research world
(1997)
Link
Alcohol-Induced Regulation of Nuclear Regulatory Factor-Kβ in Human Monocytes
(with Pranoti Mandrekar and Donna Catalano),
Alcoholism: Clinical and Experimental Research
(1997)
Link
Acute ethanol treatment augments interleukin-12 production in activated human monocytes
(with Linda Girouard, Pranoti Mandrekar, and Donna Catalano),
Annals of the New York Academy of Sciences
(1996)
Link
Regulation of human monocyte functions by acute ethanol treatment: decreased tumor necrosis factor-alpha, interleukin-1 beta and elevated interleukin-10, and transforming growth factor-beta production
(with Pranoti Mandrekar, Linda Girouard, and Donna Catalano),
Alcoholism, clinical and experimental research
(1996)
Link
Human monocyte IL-10 production is increased by acute ethanol treatment
(with Pranoti Mandrekar, Donna Catalano, and Linda Girouard),
Cytokine
(1996)
Link
NF-kB, a Prototypical Cytokine-Regulated Transcription Factor: Implications for Alcohol-Mediated Responses
(with Samir Zakhari),
Alcoholism: Clinical and Experimental Research
(1996)
Link
Inhibition of superantigen-induced T cell proliferation and monocyte IL-1 beta, TNF-alpha, and IL-6 production by acute ethanol treatment
(with Pranoti Mandrekar and Donna Catalano),
Journal of leukocyte biology
(1995)
Link
Acute ethanol consumption synergizes with trauma to increase monocyte tumor necrosis factor alpha production late postinjury
(with Pranoti Mandrekar, Bikash K. Verma, Ann Isaac, and Donna Catalano),
Journal of clinical immunology
(1994)
Link
Regulatory potential of ethanol and retinoic acid on human monocyte functions
(with Maria Puppolo, Bikash K. Verma, and Donna Catalano),
Alcoholism, clinical and experimental research
(1994)
Link
Dibutyryl-cAMP modulation of receptor expression and antigen presentation capacity in monocyte subpopulations
(with Karen Kodys and Carol L. Miller-Graziano),
International journal of immunopharmacology
(1994)
Link
Selective inhibition of antigen-specific T lymphocyte proliferation by acute ethanol exposure: the role of impaired monocyte antigen presentation capacity and mediator production
(with Bikash K. Verma and Donna Catalano),
Journal of leukocyte biology
(1993)
Link
Down-regulation of tumor necrosis factor alpha activity by acute ethanol treatment in human peripheral blood monocytes
(with Bikash K. Verma and Miklos C. Fogarasi),
Journal of clinical immunology
(1993)
Link
Induction of transforming growth factor-beta and prostaglandin E2 production by ethanol in human monocytes
(with Bikash K. Verma, Miklos C. Fogarasi, and Donna Catalano),
Journal of leukocyte biology
(1992)
Link
Elevated monocyte interleukin-6 (IL-6) production in immunosppressed trauma patients. II. Downregulation by IL-4
(with Karen Kodys and Carol L. Miller-Graziano),
Journal of clinical immunology
(1991)
Link
Elevated monocyte interleukin-6 (IL-6) production in immunosuppressed trauma patients. I. Role of Fc gamma RI cross-linking stimulation
(with Karen Kodys and Carol L. Miller-Graziano),
Journal of clinical immunology
(1991)
Link
Role of elevated monocyte transforming growth factor beta (TGF beta) production in posttrauma immunosuppression
(with Carol L. Miller-Graziano, Katherine Griffey, Bela Mehta, Karen Kodys, and Donna Catalano),
Journal of clinical immunology
(1991)
Link
Aberrations in post-trauma monocyte (MO) subpopulation: role in septic shock syndrome
(with Carol L. Miller-Graziano, Karen Kodys, and Katherine Griffey),
The Journal of trauma
(1990)
Link
Induction and regulation of monocyte procoagulant activity
(with Carol L. Miller-Graziano),
Transplantation
(1990)
Link
Differential tumor necrosis factor production by human monocyte subsets
(with Carol L. Miller-Graziano, Jia-Yan Wu, Thomas K. Takayama, and Karen Kodys),
Journal of leukocyte biology
(1990)
Link
Antigen presentation by the CD4 positive monocyte subset
(with Carol L. Miller-Graziano and Karen Kodys),
Journal of leukocyte biology
(1990)
Link
Elevated tumor necrosis factor alpha production concomitant to elevated prostaglandin E2 production by trauma patients' monocytes
(with Thomas K. Takayama and Carol L. Miller-Graziano),
Archives of surgery (Chicago, Ill. : 1960)
(1990)
Polymorphonuclear functions in patients with mixed connective tissue disease
(with E. Bodolay, Katalin Lukacs, G. Frendl, G. Arato, and Gyula Szegedi),
Allergologia et immunopathologia
(1989)
Monocyte functions in patients with mixed connective tissue disease
(with E. Bodolay, Katalin Lukacs, G. Frendl, T. Ben, and Gyula Szegedi),
Allergologia et immunopathologia
(1989)
Link
Mechanisms of altered monocyte prostaglandin E2 production in severely injured patients
(with Carol L. Miller-Graziano, Mitchell P. Fink, Jia-Yan Wu, and Karen Kodys),
Archives of surgery (Chicago, Ill. : 1960)
(1988)
Selective induction of mononuclear phagocytes to produce neopterin by interferons
(with Gabriele Bitterlich, Ernst R. Werner, C. Larcher, Dietmar Fuchs, Arno Hausen, Gilbert Reibnegger, T.F. Schulz, J. Troppmair, and Helmut Wachter),
Immunobiology
(1988)
Link
Human macrophages degrade tryptophan upon induction by interferon-gamma
(with Ernst R. Werner, Gabriele Bitterlich, Dietmar Fuchs, Arno Hausen, Gilbert Reibnegger, Manfred P. Dierich, and Helmut Wachter),
Life sciences
(1987)
Inhibitory effect of monocyte reactive antibodies on monocyte chemotaxis in systemic lupus erythematosus
(with Gyula Szegedi, Katalin Lukacs, E. Bodolay, L. Gulacsi, Ildiko Sonkoly, and J. Szollosi),
Haematologia
(1985)
Link
Effects of immune complexes from SLE patients on human monocyte locomotion and Fc receptor function
(with Katalin Lukacs, Maria Kavai, Aniko Banyai, Ildiko Sonkoly, Eva Vegh, and Gyula Szegedi),
Annals of the rheumatic diseases
(1984)
Link
Stimulating effect of tuftsin and its analogues on the defective monocyte chemotaxis in systemic lupus erythematosus
(with Katalin Lukacs, Ildiko Sonkoly, Eva Vegh, Janos Gacs, Maria Szekerke, and Gyula Szegedi),
Immunopharmacology
(1984)
Contributions to Books
Link
Toll-like Receptors
(with Pranoti Mandrekar),
Signaling Pathways in Liver Diseases
(2010)
Link
Modulation of Cytokine Production in Human Lymphoid and Myeloid Cells by Alcohol
In Vitro
(with Pranoti Mandrekar, Bikash K. Verma, and Donna Catalano),
Alcohol, Drugs of Abuse and Immune Function
(1995)
Link
Monocyte-Mediated Immunodepression after Acute Ethanol Exposure
,
Alcohol, Drugs of Abuse and Immunomodulation: proceedings of the 2nd International Conference on Alcohol, Drugs of Abuse and Immunomodulation (AIDS) held in Arizona, USA, on 9-13 September 1992
(1993)
Posters and Presentations
PDF
Caspase-1-dependent, IL-1ß-mediated alcoholic steatohepatitis is ameliorated by IL-1 receptor antagonist treatment in mice
(with Jan Petrasek, Shashi Bala, Dora Lippai, Karen Kodys, Victoria Menashy, Matthew Barrieau, and Evelyn A. Kurt-Jones),
Clinical and Translational Science Research Retreat
(2012)
PDF
CD81/CD9 tetraspanins aid plasmacytoid dendritic cells in recognition of HCV-infected cells and induction of IFNα
(with Shuye Zhang and Karen Kodys),
Clinical and Translational Science Research Retreat
(2012)
PDF
Increased oxidative capacity of circulating polymorphonuclear neutrophils (PMNs) in non-diabetic NASH patients
(with Timea Csak, Karen Kodys, Angela Dolganiuc, Dora Lippai, Michal Ganz, and Christopher Marshall),
Clinical and Translational Science Research Retreat
(2012)
PDF
Serum microRNA-122 and miR-155 as biomarkers of liver injury and inflammation in models of acute and chronic liver disease
(with Shashi Bala, Jan Petrasek, Shiv Mundkur, Donna Catalano, Jeanine Ward, Ivan Levin, Hawau Alao, and Karen Kodys),
Clinical and Translational Science Research Retreat
(2012)