Rapid transient explosive boiling of mixed ethanol and acetone of different volume fractions were investigated experimentally. The temperature of the metal film surface irradiated by a pulse laser was measured by a fast-response measurement system with a platinum film resistor. The behaviors of bubbles, including their formation, growth, departure and floating-up, were observed and captured by a microscope camera system. It was found that bubble nucleation temperature depends strongly on the heating rate. Some special characteristics different from those of conventional boiling were revealed, and the factors affecting explosive boiling were studied.