SelectedWorks - El Nasir Lalani

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El Nasir Lalani

Director, Center of Regenerative Medicine and Stem Cell Research

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About El Nasir Lalani

Present	Director, Centre for Regenerative Medicine, Aga Khan University
Institution Organization Position Type Position Title Time Period to Options Current Position Affiliate my profile with this Institution
July 2008 - July 2016	Dean of Research and Graduate Studies, Aga Khan University
Institution Organization Position Type Position Title Time Period to Options Current Position Affiliate my profile with this Institution

Education, Medicine and Health Sciences, and Pathology

Stem Cells, Epithelial-Mesenchymal transition, Epithelial Cancers, Tissue Banking

Human Cytomegalovirus: a neglected public health area of significant relevance ...

JPMA. The Journal of the Pakistan Medical Association (2017)

Amna Rehana Siddiqui, Saira Ibrahim, Anwar Ali Siddiqui, Paul Moss, et al.

Cryo-nanoscale chromosome imaging-future prospects

Biophysical Reviews (2020)

Mohammad Yusuf, Safana Farooq, Ian Robinson and El Nasir Lalani

The high-order structure of mitotic chromosomes remains to be fully elucidated. How nucleosomes compact at various structural levels into a ...

Lack of androgen receptor expression selects for basal-like phenotype and ...

Frontiers in Oncology (2020)

Nazia Riaz, Romana Idress, Sadia Habib and El Nasir Lalani

Background: Androgen receptor (AR) has emerged as a significant favorable prognostic indicator in estrogen receptor expressing (ER+) breast cancer (BCa); ...

First meeting in Asia of the Asia pacific research integrity ...

Accountability in Research (2020)

Daniel Barr, Danny Chan, Susan Garfinkel, Zoë Hammatt, et al.

In 2017, the University of Hong Kong and the University of California San Diego co-hosted the first Asian meeting of ...

Activation of AKT/mTOR pathway in Ph+ acute lymphoblastic leukemia ...

Afsar Ali Mian, Usva Zafar, Oliver Ottmann, Martin Ruthardt, et al.

Introduction: The t(9;22) (q34;q11) translocation results in the constative active BCR/ABL tyrosine kinase. Der22 involves the Breakpoint Cluster Region (BCR) ...

The ''gatekeeper'' mutation T315I in BCR/ABL confers additional oncogenic ...

Usva Zafar, Mohammed Yousuf, Rikhia Chakraborty, El Nasir Lalani, et al.

Chronic myeloid leukemia (CML) and 30% of adult acute lymphatic leukemia (ALL) are characterized by the Philadelphia chromosome (Ph+), having ...

Expression of androgen receptor and cancer stem cell markers (CD44 ...

Translational Oncology (2018)

Nazia Riaz, Romana Idress, Sadia Habib, Iqbal Azam Syed, et al.

Background: Androgen receptor (AR) has emerged as a significant prognostic marker in early breast cancer (BCa). Association of AR with ...

Sociodemographic factors associated with IgG and IgM seroprevalence for human ...

BMC Public Health (2016)

Saira Ibrahim, Anwar Ali Siddiqui, amna siddiqui, Waquaruddin Ahmed, et al.

Background: The seroprevalence of human cytomegalovirus (HCMV) infection ranges from 30 to 90 % in developed countries. Reliable estimates of ...

Correction to: Cryo-nanoscale chromosome imaging-future prospects

Biophysical Reviews (2020)

Mohammed Yousuf, Safana Farooq, Ian Robinson and El Nasir Lalani

A correction to this paper has been published: https://doi.org/10.1007/s12551-020-00767-5 .

LMP1 expression in bone marrow trephines of patients with multiple ...

Leukemia & Lymphoma (2019)

Sheerien Rajput, Khurram Minhas, Iqbal Azam Syed, Usman Shaikh, et al.

Multiple myeloma (MM) is a heterogeneous disease of the bone marrow (BM). Its association with Epstein-Barr virus (EBV) remains enigmatic. ...

Role of mesenchymal stem cells in acquisition of metaplasia in ...

Cancer Research (2017)

Nazia Riaz, Sadia Habib, Azhar Hussain and El Nasir Lalani

Introduction: Metaplastic carcinoma (MCa) is a rare and aggressive subtype of invasive breast carcinoma exhibiting epithelial to mesenchymal transition (EMT) ...

Lack of androgen receptor expression correlates with high expression of ...

Molecular Cancer Research (2016)

Nazia Riaz, Romana Idress, Sadia Habib, Syed Zulfiqar Naqvi, et al.

Introduction: A sub-population of cells referred to as cancer stem cells has been identified utilizing specific markers such as aldehyde ...

P064 expression of Tumor initiating markers in Metaplastic Carcinoma of ...

N. Riaz, Z. Naqvi, R. Idress, S M Khan, et al.

Expression of the Androgen Receptor, pAkt, and pPTEN in Breast ...

Translational Oncology (2014)

Aisha Sultana, Romana Idress, Zulfiqar Ali Naqvi, Iqbal Azam Syed, et al.

Background Importance of androgen receptor (AR) as an independent prognostic marker in Pakistani women with breast cancer (BCa) remains unexplored. ...

MP39-17 MECP2 Silencing in high grade bladder Cancer derived HTB-5 ...

Journal of Urology (2014)

Shumaila Bilgrami, Zulfiqar Naqvi, Khalid Shaikh, El-Nasir Lalani, et al.

DNA methylation patterns and chromatin structure is significantly altered in many human neoplasms including bladder cancer. Aberrant promoter hypermethylation of ...

5α-dihydrotestosterone down-regulates HER2 and sensitizes breast cancer cells to Herceptin-induced ...

Cancer Research (2014)

Aisha Sultana, Zulfiqar Ali Naqvi, Shaista Khan, Anwar Ali Siddiqui, et al.

Androgen inhibits growth of malignant breast cancer (BCa) cells by mechanisms that remain poorly defined. Here, we have investigated how ...

Androgen receptor expressing metaplastic carcinoma cell line established from non-caucasian ...

Cancer Research (2014)

Nazia Riaz, Zulfiqar Naqvi, Anwar Ali Siddiqui, Shaista Masood Khan, et al.

Background:Metaplastic carcinoma (MCa) is a rare entity of breast cancer (BCa) where tumor of epithelial origin manifests differentiation into non-glandular, ...

Expression of the androgen receptor, pAkt, and pPTEN in breast ...

Translational Oncology (2014)

Aisha Sultana, Romana Idress, Zulfiqar Ali Naqvi, Iqbal Azam, et al.

BACKGROUND: Importance of androgen receptor (AR) as an independent prognostic marker in Pakistani women with breast cancer (BCa) remains unexplored. ...

Doxazosin induces apoptosis in PTEN–positive androgen-independent PC cells via ...

Urologia Polska (2010)

Hanna M Romanska, Maciej Salagierski, Rachel Bruton, P D Abel, et al.

Doxazosin, a selective α1-adrenoreceptor antagonist widely used in the management of benign prostatic hyperplasia (BPH), has been shown to induce ...

Nuclear Magnetic Resonance Detects Phosphoinositide 3-Kinase/Akt-Independent Traits Common to ...

Neoplasia (2009)

Hanna M. Romanska, Stefano Tiziani, Rachael C. Howe, Ulrich L. Guenther, et al.

Pluripotent embryonic stem (ES) cells, a potential source of somatic precursors for cell therapies, cause tumors after transplantation. Studies of ...

CD151 Regulates Tumorigenesis by Modulating the Communication between Tumor Cells ...

Molecular Cancer Research (2009)

Rafal Sadej, Hanna Romanska, Gouri Baldwin, Katerina Gkirtzimanaki, et al.

The tetraspanin CD151 forms stoichiometric complexes with laminin-binding integrins (e.g., alpha 3 beta 1, alpha 6 beta 1, and alpha ...

Predictive value of PTEN and AR coexpression of sustained responsiveness ...

Neoplasia (2008)

Soha S. El Sheikh, Hanna M. Romanska, Paul Abel, Jan Domin, et al.

Early hormonal data from a multicentre phase II trial using ...

BJU International (2008)

Ruth E. Langley, Ian F. Godsland, Howard Kynaston, Noel W. Clarke, et al.

Objective To assess the hormonal effects of Fem7® (Merck, KGaA, Darmstadt, Germany) 100 µg transdermal oestrogen patches on men undergoing ...

Evaluation of inter-observer variability in the grading of Oral Dysplasia ...

Clinical Otolaryngology (2008)

R. T. Srinivasan, D. Snead, P. Matthews, H. Williams, et al.

Objectives To compare the inter-observer variability in grading of oral dysplasia between two consultant pathologists specialising in head and neck ...

Evaluation of inter-observer variability in the grading of oral dysplasia ...

Clinical Otolaryngology (2008)

R.T Srinivasan, D Snead, P Matthews, H Williams, et al.

Objectives: To compare the inter-observer variability in grading of oral dysplasia between two consultant pathologists specialising in head and neck ...