Statistics is concerned with guessing the unknown. A challenge in statistics is integrating classical frequentist based statistical guesses with Bayesian methods guesses. This challenge is particularly apparent when using mixed models for longitudinal data analysis, since empirical Bayes estimators such as the best linear unbiased predictor are often recommended. A simple example illustrates the dilemma. A person is asked via a 24 food record to record the total Kcal ingested. The result is a value of 6000 Kcal, well outside the range of usual values. What is the best guess of the person's typical intake? 6000 Kcal, or a value closer to the "population" norm? This broad area is the focus of my research.
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Seasonal and Sex Variation of High-Sensitivity C-Reactive Protein in Healthy Adults: A Longitudinal Study (with David E. Chiriboga, Yunsheng Ma, Wenjun Li, James R. Hébert, Philip A. Merriam, Eric S. Rawson, and Ira S. Ockene), Clinical Chemistry (2010)
BACKGROUND
Cross-sectional studies have reported seasonal variation in high-sensitivity C-reactive protein (hsCRP). However, longitudinal data...
Predicting Low Dose Effects for Chemicals in High Through-Put Studies (with E. J. Calabrese), Dose Response (2010)
High through-put studies commonly use automated systems with 96-well plates in which multiple chemicals are...
Quantification of Hormesis in Anticancer-Agent Dose-Responses (with Marc A. Nascarella, George R. Hoffmann, and Edward J. Calabrese), Dose Response (2009)
Quantitative features of dose responses were analyzed for 2,189 candidate anticancer agents in 13 strains...
Greenhouse Trials of Aphidius colemani (Hymenoptera: Braconidae) Banker Plants for Control of Aphids (Hemiptera: Aphididae) in Greenhouse Spring Floral Crops (with R. G. Van Driesche, S. Lyon, J. P. Sanderson, K. C. Bennett, and Ruitao Zhang), The Florida Entomologist (2008)
Banker plants with Aphidius colemani Viereck were tested in greenhouses in Massachusetts and New York...
Association Between Dietary Glycemic Index, Glycemic Load, and High-Sensitivity C-Reactive Protein (with Jennifer A. Griffith, Yusheng Ma, Lisa Chasan-Taber, Barbara C. Olendzki, David E. Chiriboga, Philip A. Merriam, and Ira S. Ockene), Nutrition (2008)
OBJECTIVE:
This study examined the relation between quality of dietary carbohydrate intake, as measured by...