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Cloning and expression of ADAM-related metalloproteases in equine laminitis (with M.J. Coyne, H. Cousin, J.P. Loftus, P.J. Johnson, J.K. Balknap, C.M. Gradil, and S.J. Black), Veterinary Immunology and Immunopathology (2009)

Equinelaminitis is a debilitating disease affecting the digital laminae that suspend the distal phalanx within...

 

ADAM function in embryogenesis (with C. McCusker and H. Cousin), Seminars in Cell & Developmental Biology (2009)

Cleavage of proteins inserted into the plasma membrane (shedding) is an essential process controlling many...

 

Xenopus ADAM19 is involved in neural, neural crest and muscle development (with R. Neuer, H. Cousin, C. McCusker, and M. Coyne), Mechanisms of Development (2009)

ADAM19 is a member of the meltrin subfamily of ADAM metalloproteases. In Xenopus, ADAM19 is...

 

Extracellular cleavage of cadherin-11 by ADAM metalloproteases is essential for Xenopus cranial neural crest cell migration (with C. McCusker, H. Cousin, and R. Neuner), Molecular Biology of the Cell (2009)

Cell adhesion molecules such as cadherins alternate their expression throughout cranial neural crest (CNC) development,...

 

PACSIN2 regulates cell adhesion during gastrulation in Xenopus laevis (with H. Cousin and D.W. Desimone), Developmental Biology (2008)

We previously identified the adaptor protein PACSIN2 as a negative regulator of ADAM13 proteolytic function....

 

A PTP-PEST like protein affects (alpha)5(Beta)1 integrin-dependent matrix assembly cell adhesion and migration in xenopus gastrula (with H. Cousin), Developmental Biology (2004)

During amphibian gastrulation, mesodermal cell movements depend on both cell–cell and cell–matrix interactions. Ectodermal cells...

 

Integrin (alpha)5(beta)1 supports the migration of Xenopus Cranial Neural Crest on fibronectin (with H. Cousin, A. Gaultier, B.G. Hoffstrom, and D.W. DeSimone), Developmental Biology (2003)

During early embryonic development, cranialneuralcrest cells emerge from the developing mid- and hindbrain. While numerous...

 

ADAM13 disintegrin and cysteine-rich domains bind to the Hep II domain of fibronectin (with H. Cousin, T. Darribere, and A. Gaultier), Journal of Biological Chemistry (2002)

ADAM13 is a member of the disintegrinand metalloprotease protein family that is expressed on cranial...

 

Xenopus ADAM13 is a metalloprotease required for cranial neural crest cell migration (with H. Cousin, A. Gaultier, K.M. Smith, J.M. White, T. Darribere, and D.W. DeSimone), Current Biology (2001)

Cranial neural-crest (CNC) cells originate from the lateral edge of the anterior neuroepithelium and migrate...

 

X-PACSIN2 is a regulator of the Metalloprotease/Disintegrin ADAM13 (with H. Cousin, A. Gaultier, C. Bleux, and T. Darribere), Developmental Biology (2000)

ADAM13 is a cell surface metalloprotease expressed in cephalic neural crest cells during early Xenopus...

 

ADAM 13: A Novel ADAM Expressed in Somitic Mesoderm and Neural Crest Cells during Xenopus laevis Development (with T.G. Wolfsberg, J.M. White, and D.W. DeSimone), Developmental Biology (1997)

Embryonic development involves a series of cell adhesive interactions that provide mechanical and instructive information...