Gene Knockdown Techniques
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Interferon-gamma
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
CD4-Positive T-Lymphocytes
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Digestive System
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
Sequence Alignment
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
Cell Survival
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
T-Lymphocytes
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Spleen
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Flow Cytometry
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Muscles
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
Mice, SCID
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Statistics, Nonparametric
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Xenopus Proteins
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
Insulin
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
Crosses, Genetic
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Adaptive Immunity
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Molecular Chaperones
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
Mice, Inbred BALB C
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Interleukin-4
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Amino Acid Sequence
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
Lymphocyte Activation
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Galactosylceramides
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Hedgehog Proteins
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
Humans
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
Mice, Inbred C57BL
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Interleukin Receptor Common gamma Subunit
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Transcription Factor CHOP
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Female
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Mutation
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Molecular Sequence Data
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
Mice
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Transplantation, Heterologous
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Diabetes Mellitus, Type 1
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Rats
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Zebrafish
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
Homeodomain Proteins
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
Animals
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
Mice, Knockout
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Endoplasmic Reticulum
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Hematopoietic Stem Cell Transplantation
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Specific Pathogen-Free Organisms
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Immunity, Innate
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Transplantation, Homologous
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Heat-Shock Proteins
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Islets of Langerhans Transplantation
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
*Muscle Development
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
DNA-Binding Proteins
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
Oligonucleotides
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
Hematopoietic Stem Cells
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Disease Models, Animal
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Endoderm
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
Thymus Gland
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Muscle Proteins
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
*Gene Expression Regulation, Developmental
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
Zebrafish Proteins
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
CD8-Positive T-Lymphocytes
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
GTP-Binding Proteins
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Body Patterning
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
Histocytochemistry
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Blood Glucose
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Models, Animal
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Male
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Caenorhabditis elegans Proteins
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
In Situ Hybridization
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm (with Kristen Alexa, Seong-Kyu Choe, Letitiah Etheridge, and Charles G. Sagerstrom), Developmental biology (2007)
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas...
Genes, Helminth
A zebrafish unc-45-related gene expressed during muscle development (with Letitiah Etheridge and Charles G. Sagerstrom), Developmental dynamics : an official publication of the American Association of Anatomists (2002)
We report the isolation and expression pattern of zebrafish unc45r, a gene related to Caenorhabditis...
Signal Transduction
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Sex Factors
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Diabetes Mellitus, Experimental
CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells (with Steven C. Pino, Bryan O'Sullivan-Murphy, Erich A. Lidstone, Chaoxing Yang, Kathryn L. Lipson, Agata Jurczyk, Michael A. Brehm, John P. Mordes, Dale L. Greiner, Aldo A. Rossini, and Rita Bortell), PloS one (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T...
Mice, Inbred NOD
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice (with Michael A. Brehm, Rita Bortell, Jean H. Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, and Leonard D. Shultz), Diabetes (2010)
OBJECTIVE: To create an immunodeficient mouse model that spontaneously develops hyperglycemia to serve as a...
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Interleukin-12
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat (with Prerna Chopra, Steven C. Pino, S. Brian Wilson, Nancy E. Phillips, John P. Mordes, Aldo A. Rossini, Dale L. Greiner, Leonard D. Shultz, and Rita Bortell), In vivo (Athens, Greece) (2009)
BACKGROUND: Alpha-galactosylceramide (alpha-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type...
Animals, Newborn
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation (with Michael A. Brehm, Amy Cuthbert, Chaoxing Yang, David M. Miller, Joseph Laning, Lisa M. Burzenski, Bruce Gott, Oded Foreman, Anoop Kavirayani, Mary Herlihy, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner), Clinical immunology (Orlando, Fla.) (2010)
"Humanized" mouse models created by engraftment of immunodeficient mice with human hematolymphoid cells or tissues...