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Selected Works of Pr. Mamoudou H. DICKO, PhD
Article
Phytochemical Analysis and Biological Activities of Cola nitida Bark
Biochemistry Research International (2015)
  • Durand Dah-Nouvlessounon
  • Laboratoire BAEBIB, UFR-SVT, University of Ouagadougou, Laboratoire BAEBIB, UFR-SVT, University of Ouagadougou
  • Mamoudou H. DICKO, Prof.
  • Lamine Baba-MOUSSA
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Abstract

The aim of this study is to investigate some biological effects of Cola nitida’s bark after phytochemical screening. The bark was collected, dried, and then powdered for the phytochemical screening and extractions. Ethanol and ethyl acetate extracts of C. nitida were used in this study. The antibacterial activity was tested on ten reference strains and 28 meat isolated Staphylococcus strains by disc diffusionmethod. The antifungal activity of three fungal strains was determined on the Potato-Dextrose Agar medium mixed with the appropriate extract. The antioxidant activity was determined by DPPH and ABTS methods. Our data revealed the presence of various potent phytochemicals. For the reference andmeat isolated strains, the inhibitory diameter zone was from17.5 ± 0.7mm(C. albicans) to 9.5 ± 0.7mm(P. vulgaris). The MIC ranged from 0.312 mg/mL to 5.000 mg/mL and the MBC from 0.625 mg/mL to >20mg/mL. The highest antifungal activity was observed with F. verticillioides and the lowest one with P. citrinum.The two extracts have an excellent reducing free radical activity. The killing effect of A. salina larvae was perceptible at 1.04 mg/mL. The purified extracts of Cola nitida’s bark can be used to hold meat products and also like phytomedicine.

Keywords
  • Cola nitida,
  • antioxidant,
  • antibacterial,
  • Bactericidal,
  • antimicrobial
Disciplines
Publication Date
Winter January 11, 2015
Publisher Statement
Copyright © 2015 Durand Dah-Nouvlessounon et al. This is an open access article distributed under the Creative Commons. Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation Information
Durand Dah-Nouvlessounon, Laboratoire BAEBIB, UFR-SVT, University of Ouagadougou, Mamoudou H. DICKO and Lamine Baba-MOUSSA. "Phytochemical Analysis and Biological Activities of Cola nitida Bark" Biochemistry Research International Vol. 2015 Iss. Article ID 493879 (2015)
Available at: http://works.bepress.com/dicko/48/