I am an Assistant Member in Biostatistics, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, and an Affiliate Assistant Professor in Department of Biostatistics, University of Washington. I obtained my PhD degree in Biostatistics from the Johns Hopkins University in 2009, where I worked with Drs. Kung-Yee Liang, Ciprian M. Crainiceanu and Karen Bandeen-Roche. My research interests include functional and longitudinal data analysis, hypothesis testing under nonstandard conditions, measurement error and latent variable models, and their applications in public health and medical studies. My recent collaborative research involves various projects in the Women's Health Initiative, to investigate environmental and genetic factors for cancer and cadiovascular disease. In particular, we aim to improve the measurements of diet and physical activity through objective biomarkers and accelerometers, and study their association with health outcomes.
Articles
Proportional mean residual life model for right-censored length-biased data (with Gary KWUN CHUEN Chan and Ying Qing Chen), Biometrika (2012)
To study disease association with risk factors in epidemiologic studies, cross-sectional sampling is often more...
Multilevel latent class models with Dirichlet mixing distribution (with Karen Bandeen-Roche), Biometrics (2011)
Latent class analysis (LCA) and latent class regression (LCR) are widely used for modeling multivariate...
Likelihood Ratio Testing for Admixture Models with Application to Genetic Linkage Analysis (with Kung-Yee Liang), Biometrics (2011)
We consider likelihood ratio tests (LRT) and their modifications for homogeneity in admixture models. The...
Generalized Multilevel Functional Regression (with Ciprian M. Crainiceanu and Ana-Maria Staicu), Journal of the American Statistical Association (2009)
We introduce Generalized Multilevel Functional Linear Models (GMFLMs), a novel statistical framework for regression models...
Multilevel Functional Principal Component Analysis (with Ciprian M. Crainiceanu, Brian S. Caffo, and Naresh M. Punjabi), Annals of Applied Statistics (2009)
The Sleep Heart Health Study (SHHS) is a comprehensive landmark study of sleep and its...
Unpublished Papers
Hypothesis Testing for an Extended Cox Model with Time-Varying Coefficients (with Ying Qing Chen and Takumi Saegusa), Biometrics (submitted) (2012)
In many randomized clinical trials, the log-rank test has routinely been used to detect a...
Supremum test statistics for a semi-parametric mixture case-control model (with Gary KWUN CHUEN Chan and Kung-Yee Liang), Biometrics (submitted) (2012)
Recently, Qin and Liang (Biometrics, 2011) considered a semiparametric mixture case-control model and proposed a...
MULTILEVEL SPARSE FUNCTIONAL PRINCIPAL COMPONENT ANALYSIS (with Ciprian M. Crainiceanu), Johns Hopkins University, Dept. of Biostatistics Working Papers (2010)
The basic observational unit in this paper is a function. Data are assumed to have...
Likelihood Ratio Testing for a Class of Nonidentifiable Problems (with Kung-Yee Liang) (2010)
We consider hypothesis testing problems where some nuisance parameters are present only under the alternative...
On Likelihood Ratio Tests When Nuisance Parameters are Present Only Under the Alternative (with Kung-Yee Liang) (2010)
In parametric models, when one or more parameters disappear under the null hypothesis, the likelihood...