Articles

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Improving the Selective Cancer Killing Ability of ZnO Nanoparticles Using Fe Doping (with Aaron Thurber, John W. Rasmussen, Janet Layne, Lydia Johnson, Dmitri A. Tenne, Jianhui Zhang, Charles B. Hanna, and Alex Punnoose), Nanotoxicology (2012)

This work reports a new method to improve our recent demonstration of zinc oxide (ZnO)...

 

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Enhanced Dye Fluorescence in Novel Dye–ZnO Nanocomposites (with Jianhui Zhang, Aaron Thurber, Dmitri A. Tenne, John W. Rasmussen, Charles Hanna, and Alex Punnoose), Advanced Functional Materials (2010)

New fluorescein isothiocyanate/fluorescein/rhodamine B-doped ZnO composite nanostructures including tripods, tubes, and rods with tuned sizes...

 

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Zinc Oxide Nanoparticles for Selective Destruction of Tumor Cells and Potential for Drug Delivery Applications (with John W. Rasmussen, Ezequiel Martinez, and Panagiota Louka), Expert Opinion on Drug Delivery (2010)

Importance of the field: Metal oxide nanoparticles, including zinc oxide, are versatile platforms for biomedical...

 

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Electrostatic Interactions Affect Nanoparticle-Mediated Toxicity to Gram-Negative Bacterium Pseudomonas aeruginosa PAO1 (with Kevin Feris, Caitlin Otto, Juliette Tinker, Alex Punnoose, Aaron Thurber, Madhu Kongara, Maryam Sabetian, Bonnie Quinn, Charles Hanna, and David Pink), Langmuir (2009)

Nanoscale materials can have cytotoxic effects. Here we present the first combined empirical and theoretical...

 

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The Influences of Cell Type and ZnO Nanoparticle Size on Immune Cell Cytotoxicity and Cytokine Induction (with Cory Hanley, Aaron Thurber, Charles Hanna, Alex Punnoose, and Jianhui Zhang), Nanoscale Research Letters (2009)

Nanotechnology represents a new and enabling platform that promises to provide a range of innovative...

 

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Fluorescent Dye Encapsulated ZnO Particles with Cell-Specific Toxicity for Potential Use in Biomedical Applications (with Hua Wang, Mark H. Engelhard, Kevin Feris, K. M. Reddy, Paul Turner, Janet Layne, Cory Hanley, Jason Bell, Dmitri Tenne, Chongmin Wang, and Alex Punnoose), Journal of Materials Science: Materials in Medicine (2009)

Fluorescein isothiocyanate (FITC)-encapsulated SiO2 core-shell particles with a nanoscale ZnO finishing layer have been synthesized...

 

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Preferential Killing of Cancer Cells and Activated Human T Cells Using ZnO Nanoparticles (with Cory Hanley, Janet Layne, Alex Punnoose, K. M. Reddy, Isaac Coombs, Andrew Coombs, and Kevin Feris), Nanotechnology (2008)

Nanoparticles are increasingly being recognized for their potential utility in biological applications including nanomedicine. Here...

 

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In vitro and in vivo Immunosuppressive Activity of a Novel Anthracycline, 13-deoxy, 5-iminodoxorubicin (with Richard D. Olson, Mark B. Headley, Alma Hodzic, and Gerald M. Walsh), International Immunopharmacology (2007)

We report that the novel anthracycline analog, 13-deoxy, 5-iminodoxorubicin (DIDOX), represents a potentially new class...

 

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Selective Toxicity of Zinc Oxide Nanoparticles to Prokaryotic and Eukaryotic Systems (with K. M. Reddy, Kevin Feris, Jason Bell, Cory Hanley, and Alex Punnoose), Applied Physics Letters (2007)

We report on the toxicity of ZnO nanoparticles (NPs) to gram-negative and gram-positive bacterial systems,...

 

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Differential Regulation of Soluble and Membrane CD40L Proteins in T Cells (with Kelli M. G. Matthies, Jodie L. Newman, and Alma Hodzic), Cellular Immunology (2006)

CD40 ligand is an important immunoregulatory protein expressed by T cells. This protein exists as...

 

Intensive Care and Invasive Ventilation in the Elderly Patient, Implications of Chronic Lung Disease and Comorbidities (with Christopher Nielson), Chronic Respiratory Disease (2004)

Elderly patients have an increasing prevalence of illness that requires consideration of critical care and...

 

Divergence in NK Cell and Cyclic AMP Regulation of T Cell CD40L Expression in Asthmatic Subjects, Journal of Leukocyte Biology (2003)

T cells are central in the pathogenesis of asthma, and the associated ligand, CD40L, plays...

 

Presentations

Air Quality and You: The Role of Diesel Exhaust Particles in Immune System Activation (with A. Masterson), National Science Foundation GK-12 Annual Meeting (2009)
 

Antimicrobial Effects and Mechanisms of Toxicity of Metal Oxide Nanoparticles (with Keven Feris, Jason Bell, Madhu Kongara, Isaac Coombs, Hua Wang, Cory Hanley, and Alex Punnoose), Association for the Advancement of Science (AAAS), Pacific Division, 88th Annual Meeting (2007)

Recent indications of nanoscale (<100 >nm) metal oxide toxicity and their increased presence in the...